Generic Name: Sectral Brand Name(s): Generics only. No brands available.


What is Sectral® (acebutolol) used for?

Sectral ® is commonly used for treating high blood pressure. It may be used alone or in combination with other medicines.

It is also used to treat certain kinds of irregular heartbeat. It may also be used for other conditions as determined by your doctor.

How should I take Sectral® (acebutolol)?

Take Sectral® by mouth with or without food.

Taking Sectral® at the same time each day will help you remember to take it.

Continue to take Sectral® even if you feel well. Do not miss any doses.

Ask your health care provider any questions you may have about how to use Sectral®.

How do I store Sectral® (acebutolol)?

Sectral® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Sectral® in the bathroom or the freezer. There may be different brands of Sectral® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Sectral® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Sectral® (acebutolol)?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of Sectral® or other medications.
  • You have any other illnesses, disorders, or medical conditions.

Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel “normal.” Tell your doctor if you develop any new symptoms.

Diabetes patients: Acebutolol may hide signs of low blood sugar, such as a rapid heartbeat. Be sure to watch for other signs of low blood sugar. Low blood sugar may make you anxious, sweaty, weak, dizzy, drowsy, or faint. It may also make your vision change; give you a headache, chills, or tremors; or make you hungry. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.

Do not suddenly stop taking acebutolol. Sharp chest pain, irregular heartbeat, and sometimes a heart attack may occur if you suddenly stop acebutolol. The risk may be greater if you have certain types of heart disease. Your doctor should slowly lower your dose over several weeks if you need to stop taking it. This should be done even if you only take acebutolol for high blood pressure. Heart disease is common and you may not know you have it. Limit physical activity while you are lowering your dose. If new or worsened chest pain or other heart problems occur, contact your doctor right away. You may need to start taking acebutolol again.

If you have a history of any severe allergic reaction, talk with your doctor. You may be at risk of an even more severe allergic reaction if you come into contact with the substance that caused your allergy. Some medicines used to treat severe allergies may also not work as well while you are using acebutolol.

If you have high blood pressure, do not use nonprescription products that contain stimulants. These products may include diet pills or cold medicines, including nasal sprays. Contact your doctor if you have any questions or concerns.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using Sectral® during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Sectral®. Sectral® is pregnancy risk category B; D (in 2nd and 3rd trimesters), according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from Sectral® (acebutolol)?

Check with your doctor if any of these most common side effects persist or become bothersome:

  • Constipation
  • Diarrhea
  • Dizziness or lightheadedness
  • Frequent urination
  • Gas
  • Headache
  • Indigestion
  • Mild drowsiness
  • Nausea
  • Sleepiness
  • Sleeplessness
  • Unusual tiredness or weakness

Seek medical attention right away if any of these severe side effects occur:

  • Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue)
  • Chest pain or tightness
  • Dark urine
  • Difficulty breathing, especially when lying down
  • Mental or mood changes
  • Pale stools
  • Persistent muscle or joint pain
  • Persistent nausea or loss of appetite
  • Shortness of breath
  • Swelling of the hands, ankles, or feet
  • Unusually slow heartbeat
  • Yellowing of the skin or eyes

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with Sectral® (acebutolol)?

Sectral® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products may interact with this drug, including:

  • Digoxin, diltiazem, disopyramide, fingolimod, flecainide, ketanserin, mibefradil, or reserpine because side effects, such as severe low blood pressure or slow heart rate, may occur.
  • Mefloquine or verapamil because the risk of serious heart problems may be increased.
  • Certain cold medicines, decongestant nasal sprays (e.g., oxymetazoline), or diet medicines because severe high blood pressure may occur.
  • Clonidine because high blood pressure may occur in some cases, especially if you suddenly stop taking clonidine while taking acebutolol.
  • Indomethacin or nonsteroidal anti-inflammatory drugs (NSAIDs) (e.g., ibuprofen) because they may decrease acebutolol’s effectiveness.
  • Flecainide, hydralazine, ketanserin, or quinazolines (e.g., alfuzosin) because the risk of their side effects may be increased by acebutolol.

Does food or alcohol interact with Sectral® (acebutolol)?

Sectral® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Sectral® (acebutolol) ?

Sectral® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

These health conditions are:

  • Heart failure
  • Other heart problems (e.g., slow heart rate, valve disease, ventricular problems)
  • Low blood pressure
  • Blood vessel problems (e.g., narrowing of the blood vessels)
  • Breathing or lung problems (e.g., bronchitis, asthma, chronic obstructive pulmonary disease)
  • Diabetes
  • An overactive thyroid
  • Liver or kidney problems
  • Adrenal gland problems (e.g., pheochromocytoma)
  • A history of any severe allergic reaction
  • Surgery


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Sectral® (acebutolol).

What is the dose of Sectral® (acebutolol) for an adult?


Hypertension: The recommended dose is 400-1200 mg/day divided PO q12hr; not to exceed 1200 mg/day.

Ventricular Arrhythmias: The recommended dose is 400-1200 mg/day divided PO q12hr; not to exceed 1200 mg/day.

Angina: The recommended dose is 400-1200 mg/day divided PO q12hr; not to exceed 1200 mg/day.


Hypertension: Initial dose is 200-400 mg PO daily; not to exceed 800 mg/day.

Ventricular Arrhythmias: Initial dose is 200-400 mg PO daily; not to exceed 800 mg/day.

Angina: Initial dose is 200-400 mg PO daily; not to exceed 800 mg/day.

What is the dose of Sectral® (acebutolol) for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Sectral® (acebutolol) available?

Sectral® is available in the following dosage forms and strengths:

  • Capsules 200mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Sectral®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

msBahasa Malaysia

Review Date: May 15, 2017 | Last Modified: May 15, 2017

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