Rovacor

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Generic Name: Rovacor Brand Name(s): Generics only. No brands available.

Uses

What is Rovacor® (lovastatin) used for?

Rovacor® is commonly used for lowering cholesterol in certain patients. It is used along with an appropriate diet.

It is used in certain patients to reduce the risk of heart attack and chest pain caused by angina. It is also used to slow blood vessel blockage and to reduce the need for medical procedures to open blocked heart blood vessels.

Rovacor® may also be used for other conditions as determined by your doctor.

How should I take Rovacor® (lovastatin)?

Take lovastatin by mouth with food. Drink with a full glass of water. Do not chew or crush.

Continue to take lovastatin even if you feel well. Do not miss any doses.

Ask your health care provider any questions you may have about how to use lovastatin.

How do I store Rovacor® (lovastatin)?

Rovacor® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Rovacor® in the bathroom or the freezer. There may be different brands of Rovacor® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Rovacor® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Rovacor® (lovastatin)?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of Rovacor® or other medications.
  • You have any other illnesses, disorders, or medical conditions.

Eating grapefruit or drinking grapefruit juice may increase the amount of lovastatin in your blood, which may increase your risk for serious side effects. The risk may be greater with large amounts of grapefruit or grapefruit juice. Avoid large amounts of grapefruit or grapefruit juice (e.g., more than one quart daily). Talk with your doctor or pharmacist if you have questions about including grapefruit or grapefruit juice in your diet while you are taking lovastatin

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using Rovacor® during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Rovacor®. Rovacor® is pregnancy risk category X, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from Rovacor® (lovastatin)?

Check with your doctor if any of these most common side effects persist or become bothersome:

  • Constipation

Seek medical attention right away if any of these severe side effects occur:

  • Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness)
  • Burning, numbness, or tingling
  • Chest pain
  • Confusion
  • Decreased urination
  • Fever, chills, or persistent sore throat
  • Memory problems
  • Mental or mood changes (e.g., depression)
  • Muscle pain, tenderness, or weakness (with or without fever or fatigue)
  • Red, swollen, blistered, or peeling skin
  • Severe stomach or back pain (with or without nausea or vomiting)
  • Shortness of breath
  • Symptoms of liver problems (e.g., dark urine; pale stools; severe or persistent nausea, loss of appetite, or stomach pain; unusual tiredness; yellowing of the skin or eyes)
  • Tremor
  • Unusual bruising or bleeding
  • Unusual tiredness or weakness

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Rovacor® (lovastatin)?

Rovacor® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products may interact with this drug, such as:

  • Amiodarone
  • Azole antifungals (e.g., fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole)
  • Boceprevir
  • Cobicistat
  • Colchicine
  • Cyclosporine
  • Danazol
  • Diltiazem
  • Dronedarone
  • Fibrates (e.g., gemfibrozil, fenofibrate)
  • HIV protease inhibitors (e.g., ritonavir)
  • Macrolide antibiotics (e.g., clarithromycin, erythromycin)
  • Nefazodone
  • Niacin
  • Ranolazine
  • Telaprevir
  • Telithromycin
  • Verapamil
  • Anticoagulants (e.g., warfarin), cimetidine, or spironolactone

Does food or alcohol interact with Rovacor® (lovastatin)?

Rovacor® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Rovacor® (lovastatin)?

Rovacor® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

These health conditions are:

  • Low blood pressure
  • Kidney problems
  • Diabetes
  • Low thyroid function
  • Muscle problems (e.g., pain, weakness)
  • Metabolism problems
  • Hormonal problems
  • Electrolyte problems
  • A history of seizures
  • Liver problems
  • Alcohol abuse
  • A certain type of high cholesterol (homozygous familial hypercholesterolemia)
  • A major surgery
  • A serious injury
  • A serious infection
  • An organ transplant

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Rovacor® (lovastatin).

What is the dose of Rovacor® (lovastatin) for an adult?

The starting dose is 20 mg once a day given with the evening meal.

The recommended dosing is 10 to 80 mg/day in single or two divided doses.

The maximum recommended dose is 80 mg/day.

Doses should be individualized according to the recommended goal of therapy.

What is the dose of Rovacor® (lovastatin) for a child?

10-17 years: The recommended dose is 20-40 mg PO qDay; not to exceed 40 mg/day.

Initiate with 10 mg/day if patient requires smaller LDL-C reduction.

How is Rovacor® (lovastatin) available?

Rovacor® is available in the following dosage forms and strengths:

  • Rovacor® 10mg tablets
  • Rovacor® 20mg tablets

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Rovacor®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

 

Sources

Review Date: May 15, 2017 | Last Modified: May 15, 2017

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