Retapamulin

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Generic Name: Retapamulin Brand Name(s): Generics only. No brands available.

Uses

What is Retapamulin used for?

Retapamulin is used to treat a certain skin infection (impetigo) caused by bacteria. It is an antibiotic that works by stopping the growth of certain bacteria (Staphylococcus and Streptococcus) on the skin.

How should I take Retapamulin?

Use this medication on the skin only. Clean and dry the affected area first. Then apply a small amount of ointment to the affected area, usually 2 times a day for 5 days or as directed by your doctor. Wash your hands after applying unless you are treating an area on the hands.

Do not use this medication around the eyes, nose, mouth, or vaginal area, or on large areas of skin, unless otherwise directed by your doctor. You may cover the treated area with a bandage/gauze. This may help prevent your child from accidentally getting the medication in their eyes, nose, or mouth.

Use this medication regularly in order to get the most benefit from it. Continue to use it for the full time prescribed. Stopping the medication too early may allow bacteria to continue to grow, which may result in a return of the infection.

You should see some improvement (healed/dry sores, decreased redness) in 3 to 4 days. Tell your doctor if your condition does not improve in 3 to 4 days.

How do I store Retapamulin?

Retapamulin is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Retapamulin in the bathroom or the freezer. There may be different brands of Retapamulin that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Retapamulin down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Retapamulin?

Before using retapamulin, tell the doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell the doctor or pharmacist your medical history.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.

Is it safe during pregnancy or breast-feeding?

There are no adequate studies in women for determining risk when using this Retapamulin during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Retapamulin. Retapamulin is pregnancy risk category B according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk,
  • B=No risk in some studies,
  • C=There may be some risk,
  • D=Positive evidence of risk,
  • X=Contraindicated,
  • N=Unknown

Side effects

What side effects can occur from Retapamulin?

Mild burning, stinging, or itching may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if any of these unlikely but serious side effects occur: blistering/swelling/oozing skin.

Use of this medication for prolonged or repeated periods may result in a new infection (e.g., fungal infection). Contact your doctor if you notice signs of a new infection (e.g., new/worsening sores, fever).

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Retapamulin?

Retapamulin may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Retapamulin?

Retapamulin may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Retapamulin?

Retapamulin may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using this Retapamulin.

What is the dose of Retapamulin for an adult?

Usual Adult Dose for Impetigo

Apply a thin layer to the affected area (up to 100 cm2 in total area) twice a day for 5 days

Comments:

-Consider alternative therapy if there is no improvement or worsening in the affected area after 2 to 3 days of treatment.

Use: Topical treatment of impetigo due to methicillin-susceptible Staphylococcus aureus or Streptococcus pyogenes

Other Comments

Administration advice:

-The treated area may be covered by a sterile bandage or gauze dressing.

-Concomitant use with other topical medicinal products to the same affected area has not been studied and is not recommended.

Patient advice:

-Wash your hands before and after use.

-Clean and dry the affected area before use.

-Put a thin layer on the affected area and rub in gently.

-Use on your skin only. Do not take this drug by mouth and keep it out of your eyes, nose, and genital area.

-Contact your doctor if the treated area worsens in irritation, redness, itching, burning, swelling, blistering, or oozing.

What is the dose of Retapamulin for a child?

Usual Pediatric Dose for Impetigo

Apply a thin layer to the affected area (up to 2% total body surface area) twice a day for 5 days

Comments:

-For pediatric patients aged 9 months or older.

-Concomitant use with strong CYP450 3A4 inhibitors is not recommended in patients younger than 24 months of age due to the higher systemic exposure of the drug in this patient population.

-Consider alternative therapy if there is no improvement or worsening in the affected area after 2 to 3 days of treatment.

Use: Topical treatment of impetigo due to methicillin-susceptible Staphylococcus aureus or Streptococcus pyogenes

Precautions

Safety and efficacy have not been established in patients younger than 9 months.

How is Retapamulin available?

Retapamulin is available in the following dosage forms and strengths:

  • Topical ointment.

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Retapamulin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: April 21, 2018 | Last Modified: April 21, 2018

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