Generic Name: Protoloc Brand Name(s): Generics only. No brands available.

Uses

What is Protoloc® (omeprazole) used for?

Omeprazole is in a class of medications called proton-pump inhibitors. It works by decreasing the amount of acid made in the stomach.

Omeprazole is used alone or with other medications to treat the symptoms of gastroesophageal reflux disease (GERD), allow the esophagus to heal, and prevent further damage to the esophagus.

How should I take Protoloc® (omeprazole)?

To take this drug,

  • Take this product by mouth as directed. Follow all directions on the product package.
  • If you are uncertain about any of the information, consult your doctor or pharmacist.

How do I store Protoloc® (omeprazole)?

Protoloc® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Protoloc® in the bathroom or the freezer. There may be different brands of Protoloc® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Protoloc® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Protoloc® (omeprazole)?

Before using this drug, tell your doctor if:

  • You plan to take nonprescription omeprazole.
  • You are allergic to omeprazole, dexlansoprazole (Dexilant), esomeprazole (Nexium), lansoprazole (Prevacid), pantoprazole (Protonix), rabeprazole (Aciphex), any other medications, or any of the ingredients in the omeprazole product you will be taking.
  • Your heartburn has lasted 3 months or longer.
  • You have experienced any of the following symptoms:
    • Lightheadedness, sweating, or dizziness along with your heartburn
    • Chest pain or shoulder pain
    • Shortness of breath or wheezing
    • Pain on your arms, neck, or shoulders
    • Unexplained weight loss
    • Nausea
    • Vomiting, especially if the vomit is bloody
    • Stomach pain
    • Difficulty swallowing food or pain when you swallow food
    • Black or bloody stools
  • You have or have ever had a low level of magnesium in your blood or liver disease.
  • You are 50 years of age or older.

Is it safe during pregnancy or breastfeeding?

There isn’t enough information about the safety of using Protoloc® during pregnancy and breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Protoloc®.

Side effects

What side effects can occur from Protoloc® (omeprazole)?

Omeprazole may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • Constipation
  • Gas
  • Nausea
  • Vomiting
  • Headache

Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately, or get emergency medical help:

  • Rash
  • Hives
  • Itching
  • Swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
  • Difficulty breathing or swallowing
  • Hoarseness
  • Irregular, fast, or pounding heartbeat
  • Excessive tiredness
  • Dizziness
  • Lightheadedness
  • Muscle spasms
  • Uncontrollable shaking of a part of the body
  • Seizures
  • Diarrhea with watery stools
  • Stomach pain
  • Fever

Some people who take omeprazole for a long time may develop weakening of the stomach lining.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Protoloc® (omeprazole)?

Protoloc® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products may interact with this drug, including:

  • Rilpivirine (Edurant, in Complera, Odefsey)
  • Certain antibiotics, including ampicillin (Principen, in Unasyn)
  • Anticoagulants (blood thinners) such as warfarin (Coumadin)
  • Atazanavir (Reyataz)
  • Benzodiazepines such as diazepam (Valium)
  • Cilostazol (Pletal)
  • Clopidogrel (Plavix)
  • Cyclosporine (Neoral, Sandimmune)
  • Digoxin (Lanoxicaps, Lanoxin) disulfiram (Antabuse)
  • Diuretics (water pills)
  • Iron supplements
  • Ketoconazole (Nizoral)
  • Methotrexate (Rheumatrex, Trexall)
  • Nelfinavir (Viracept)
  • Phenytoin (Dilantin)
  • Saquinavir (Invirase)
  • Tacrolimus (Prograf)
  •  Variconazole (Vfend)
  • Other prescription antifungal or anti-yeast medications

Does food or alcohol interact with Protoloc® (omeprazole)?

Protoloc® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Protoloc® (omeprazole)?

Protoloc® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Protoloc® (omeprazole).

What is the dose of Protoloc® (omeprazole) for an adult?

Duodenal ulcer:

The recommended dose is 20 mg orally once a day before a meal. Most patients heal within 4 to 8 weeks.

Helicobacter pylori infection:

Dual therapy: The recommended dose is omeprazole 40 mg orally once a day in the morning plus clarithromycin 500 mg orally 3 times a day on days 1 to 14. Beginning on day 15, omeprazole 20 mg orally once a day in the morning on days 15 to 28.
Triple therapy: The recommended dose is omeprazole 20 mg plus clarithromycin 500 mg plus amoxicillin 1000 mg all given orally twice a day for 10 days. If an ulcer is present at the initiation of therapy, continue omeprazole 20 mg orally once a day for an additional 18 days.

Gastric ulcer:

The recommended dose is 40 mg orally once a day before a meal for 4 to 8 weeks.

Erosive esophagitis:

The recommended dose is 20 mg orally once a day before a meal. This dosage may be increased to 40 mg per day based on desired clinical response and patient tolerance.

Zollinger-Ellison syndrome:

Initially, the recommended dose is 60 mg orally once a day. Dosage should be individualized to patient’s needs.
Maintenance, doses up to 120 mg 3 times a day have been administered. Daily doses greater than 80 mg should be divided.

Gastroesophageal reflux disease:

Initially, the recommended dose is 20 mg orally once a day before a meal for 4 to 8 weeks. This dosage may be increased to 40 mg per day if needed.

Maintenance, long-term treatment with doses of 10 to 20 mg per day may be required for maintenance therapy of refractory disease and appears to be safe.

Multiple endocrine adenomas:

Initially, the recommended dose is 60 mg orally once a day before a meal. This dosage may be titrated based on desired clinical response and patient tolerance.
Maintenance, doses up to 120 mg 3 times a day have been administered. Daily doses greater than 80 mg should be divided.

Systemic mastocytosis:

Initially, the recommended dose is 60 mg orally once a day before a meal. This dosage may be titrated based on desired clinical response and patient tolerance.
Maintenance, doses up to 120 mg 3 times a day have been administered. Daily doses greater than 80 mg should be divided.

Dyspepsia:

Prevention of frequent heartburn, the recommended dose is 20 mg orally once daily, before a meal, for 14 days.

What is the dose of Protoloc® (omeprazole) for a child?

Gastroesophageal reflux disease:

Infants:
The recommended dose is 0.7 mg/kg/dose once daily.

GERD, ulcers, esophagitis:
Children and adolescents 1 to 16 years:

  • The recommended dose is 5 mg once daily (5 kg to less than 10 kg).
  • The recommended dose is 10 mg once daily (10 kg to less than or equal to 20 kg).
  • The recommended dose is 20 mg once daily (greater than 20 kg).

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Protoloc® (omeprazole) available?

Protoloc® is available in the following dosage forms and strengths:

  • Protoloc® 20mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

Symptoms of overdose may include the following:

  • Confusion
  • Drowsiness
  • Blurred vision
  • Fast or pounding heartbeat
  • Nausea
  • Vomiting
  • Sweating
  • Flushing (feeling of warmth)
  • Headache
  • Dry mouth

What should I do if I miss a dose?

If you miss a dose of Protoloc®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: January 13, 2017 | Last Modified: January 13, 2017