What is Profenid® (ketoprofen) used for?
Profenid® is commonly used for the long-term treatment of certain cases of chronic inflammatory joint disease, and certain cases of severe osteoarthritis.
It is also indicated in the short-term treatment of:
- Certain types of inflammation around the joints (tendinitis, bursitis, acute shoulder pain)
- Certain types of joint inflammation due to crystal deposits, such as gout
- Acute osteoarthritic pain
- Acute lower back pain
- Acute pain due to irritation of a nerve, such as sciatica
- Pain and edema due to trauma
How should I take Profenid® (ketoprofen)?
Take Profenid® by mouth. It may be taken with food if it upsets your stomach. Taking it with food may not lower the risk of stomach or bowel problems (e.g., bleeding, ulcers). Talk with your doctor or pharmacist if you have persistent stomach upset.
Take Profenid® with a full glass of water (240 mL) as directed by your doctor.
How do I store Profenid® (ketoprofen)?
Profenid® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Profenid® in the bathroom or the freezer. There may be different brands of Profenid® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.
You should not flush Profenid® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.
Precautions & warnings
What should I know before using Profenid® (ketoprofen)?
Before using ketoprofen, tell your doctor if:
- You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
- You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
- You have allergy with any of active or inactive ingredients of Profenid® or other medications.
- You have any other illnesses, disorders, or medical conditions.
- You have had a severe allergic reaction (e.g., severe rash, hives, trouble breathing, growths in the nose, dizziness) to aspirin or an NSAID (e.g., ibuprofen, celecoxib).
- You have recently had or will be having bypass heart surgery.
- You are also taking probenecid.
- You are in the last 3 months of pregnancy.
- You have poor health, dehydration or low fluid volume, or low blood sodium levels, you drink alcohol, or you have a history of alcohol abuse.
Profenid® may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Profenid® with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Serious stomach ulcers or bleeding can occur with the use of Profenid®. Taking it in high doses, for a long time, smoking, or drinking alcohol increases the risk of these side effects.
Taking Profenid® with food will not reduce the risk of these effects. If you have severe stomach or back pain; black, tarry stools; vomit that looks like blood or coffee grounds; or unusual weight gain or swelling, contact your doctor or emergency room right away.
Do not take more than the recommended dose or use for longer than prescribed without checking with your doctor.
Profenid® is an NSAID. Before you start any new medicine, check the label to see if it has an NSAID (e.g., ibuprofen) in it too. If it does or if you are not sure, check with your doctor or pharmacist.
Do not take aspirin while you are using Profenid® unless your doctor tells you to.
Lab tests, including kidney function, complete blood cell counts, and blood pressure, may be performed while you use Profenid®. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
Use Profenid® with caution in the elderly; they may be more sensitive to its effects, especially stomach bleeding and kidney problems.
Profenid® should be used with extreme caution in children younger than 18 years old; safety and effectiveness in these children have not been confirmed.
Is it safe during pregnancy or breastfeeding?
Profenid® may cause harm to the fetus. Do not use it during the last 3 months of pregnancy. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Profenid® while you are pregnant.
It is not known if this medicine is found in breastmilk. Do not breastfeed while taking Profenid®.
What side effects can occur from Profenid® (ketoprofen)?
All medicines can cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most common side effects persist or become bothersome:
- Stomach upset
Seek medical attention right away if any of these severe side effects occur:
- Tightness in the chest
- Swelling of the mouth, face, lips, or tongue
- Bloody or black, tarry stools
- Change in the amount of urine produced
- Chest pain
- Dark urine
- Fast or irregular heartbeat
- Fever, chills, or persistent sore throat
- Mental or mood changes
- Numbness of an arm or leg
- One-sided weakness
- Red, swollen, blistered, or peeling skin
- Ringing in the ears
- Severe headache or dizziness
- Severe or persistent stomach pain or nausea
- Severe vomiting
- Shortness of breath
- Sudden or unexplained weight gain
- Swelling of hands, legs, or feet
- Unusual bruising or bleeding
- Unusual joint or muscle pain
- Unusual tiredness or weakness
- Vision or speech changes
- Vomit that looks like coffee grounds
- Yellowing of the skin or eyes
Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.
What drugs may interact with Profenid® (ketoprofen)?
Profenid® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.
Products may interact with this drug, including:
- Anticoagulants (e.g., warfarin), aspirin, corticosteroids (e.g., prednisone), heparin, or selective serotonin reuptake inhibitors (SSRIs) (e.g., fluoxetine) because risk of stomach bleeding may be increased.
- Probenecid because it may increase the risk of ketoprofen’s side effects.
- Cyclosporine, lithium, methotrexate, quinolones (e.g., ciprofloxacin), or sulfonylureas (e.g., glipizide) because the risk of their side effects may be increased by ketoprofen.
- Angiotensin-converting enzyme (ACE) inhibitors (e.g., enalapril) or diuretics (e.g., furosemide, hydrochlorothiazide) because their effectiveness may be decreased by ketoprofen.
Does food or alcohol interact with Profenid® (ketoprofen)?
Profenid® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.
What health conditions may interact with Profenid® (ketoprofen)?
Profenid® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.
These health conditions may include:
- A history of kidney or liver disease
- Stomach or bowel problems (e.g., bleeding, perforation, ulcers)
- A history of swelling or fluid buildup
- Growths in the nose (nasal polyps)
- Mouth inflammation
- High blood pressure
- Blood disorders (e.g., low blood albumin levels)
- Bleeding or clotting problems
- Heart problems (e.g., heart failure)
- Blood vessel disease
The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Profenid® (ketoprofen).
What is the dose of Profenid® (ketoprofen) for an adult?
The dosage depends on the indication. It varies between three to six 50 mg capsules per day, i.e. 150 to 300 mg per day.
The capsules must be taken during a meal.
The daily dosage is to be divided into 2 to 3 intakes per day.
In all cases, strictly follow your doctor’s prescription.
What is the dose of Profenid® (ketoprofen) for a child?
The dosage has not been established in pediatric patients under 15 years old. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.
How is Profenid® (ketoprofen) available?
Profenid® is available in the following dosage forms and strengths:
- Profenid® 50mg capsules
What should I do in case of an emergency or overdose?
In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.
What should I do if I miss a dose?
If you miss a dose of Profenid®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.
Hello Health Group does not provide medical advice, diagnosis or treatment.
Profenid® 50mg capsules. http://www.oubari.com/en/products/profenid-50-mg-capsules/. Accessed December 14, 2016
Ketoprofen. https://www.drugs.com/cdi/ketoprofen.html. Accessed December 14, 2016.
Review Date: April 20, 2017 | Last Modified: April 20, 2017