Plendil

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Generic Name: Plendil Brand Name(s): Generics only. No brands available.

Uses

What is Plendil® (felodipine) used for?

Plendil® is in a class of drugs called calcium channel blockers. Felodipine relaxes (widens) your blood vessels (veins and arteries), which makes it easier for the heart to pump and reduces its workload.

Plendil® is used to treat hypertension (high blood pressure).

How should I take Plendil® (felodipine)?

Take Plendil® exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results.

You make Plendil® without food or a light meal, but take it the same way each time.

How do I store Plendil® (felodipine)?

Plendil® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Plendil® in the bathroom or the freezer. There may be different brands of Plendil® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Plendil® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Plendil® (felodipine)?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of Plendil® or other medications.
  • You have any other illnesses, disorders, or medical conditions.
  • You have liver disease or congestive heart failure.

Your blood pressure will need to be checked often and you may need other blood tests at your doctor’s office. Visit your doctor regularly.

Keep using Plendil® as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.

Brush and floss your teeth regularly while taking this medication. Plendil® can cause mild swelling of your gums, which may be avoided with good dental hygiene.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using this medication during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking this medication. This medication is pregnancy risk category C, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from Plendil® (felodipine)?

Get emergency medical help if you have any of these signs of an allergic reaction to Plendil® hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

  • Feeling like you might pass out
  • Feeling short of breath, swelling in your hands or feet
  • Fast or pounding heartbeats
  • Numbness or tingly feeling
  • Chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling

Less serious side effects may include:

  • Headache, dizziness, drowsiness, weakness
  • Feeling restless or nervous
  • Nausea, upset stomach, constipation, diarrhea, stomach pain
  • Sleep problems (insomnia)
  • Joint pain or muscle cramps
  • Warmth, redness, or tingly feeling under your skin
  • Mild rash
  • Urinating more than usual
  • Cold symptoms such as stuffy nose, sneezing, sore throat

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Plendil® (felodipine)?

Plendil® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products may interact with this drug are:

  • Cimetidine (Tagamet)
  • Conivaptan (Vaprisol)
  • Imatinib (Gleevec)
  • Isoniazid (for treating tuberculosis)
  • Tacrolimus (Prograf)
  • An antibiotic such as clarithromycin (Biaxin), dalfopristin/quinupristin (Synercid), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), or telithromycin (Ketek)
  • Antifungal medication such as clotrimazole (Mycelex Troche), itraconazole (Sporanox), ketoconazole (Nizoral), or voriconazole (Vfend)
  • An antidepressant such as nefazodone
  • A beta-blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), timolol (Blocadren), and others
  • HIV/AIDS medicine such as atazanavir (Reyataz), delavirdine (Rescriptor), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), saquinavir (Invirase), or ritonavir (Norvir)
  • Other heart or blood pressure medications such as diltiazem (Cartia, Cardizem), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan), and others
  • Seizure medication such as carbamazepine (Carbatrol, Tegretol), phenobarbital (Solfoton), or phenytoin (Dilantin)

Does food or alcohol interact with Plendil® (felodipine)?

Plendil® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Plendil® (felodipine)?

Plendil® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Plendil® (felodipine).

What is the dose of Plendil® (felodipine) for an adult?

The recommended starting dose is 5 mg once a day. Depending on the patient’s response, the dosage can be decreased to 2.5 mg or increased to 10 mg once a day.

These adjustments should occur generally at intervals of not less than 2 weeks. The recommended dosage range is 2.5−10 mg once daily.

In clinical trials, doses above 10 mg daily showed an increased blood pressure response but a large increase in the rate of peripheral edema and other vasodilatory adverse events

What is the dose of Plendil® (felodipine) for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Plendil® (felodipine) available?

Plendil® is available in the following dosage forms and strengths:

  • Tablet 2,5mg, 5mg, 10mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Plendil®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

msBahasa Malaysia

Review Date: August 11, 2017 | Last Modified: September 2, 2017

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