Generic Name: Pindolol Brand Name(s): Generics only. No brands available.

Uses

What is Pindolol used for?

Pindolol is used alone or with other medications to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems. Pindolol belongs to a class of medications called beta-blockers. It works by blocking the effects of certain natural substances (such as epinephrine) on the heart and blood vessels. This results in a lowering of the heart rate, blood pressure, and strain on the heart.

How should I take Pindolol?

Take this medication by mouth with or without food, usually twice daily or as directed by your doctor.

The dosage is based on your medical condition and response to therapy. It may take 1-2 weeks before the full benefit of this drug takes effect. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick.

Use this medication regularly in order to get the most benefit from it. To help you remember, use it at the same times each day.

Inform your doctor if your condition persists or worsens (e.g., routine blood pressure readings increase).

How do I store Pindolol?

Pindolol is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Pindolol in the bathroom or the freezer. There may be different brands of Pindolol that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Pindolol down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Pindolol?

Before taking pindolol, tell your doctor or pharmacist if you are allergic to it; or to other beta-blockers (e.g., acebutolol); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: severe allergic reactions (e.g., anaphylaxis), breathing problems (e.g., asthma, chronic obstructive lung disease-COPD, emphysema, chronic bronchitis), blood circulation problems (e.g., Raynaud’s disease, peripheral vascular disease), low blood flow to the heart/brain (e.g., due to coronary artery disease, stroke, transient ischemic attack), diabetes, heart problems (e.g., heart failure, heart attack, slow heartbeat), kidney disease, liver disease, mental/mood disorders (e.g., depression), a certain muscle problem (myasthenia gravis), overactive thyroid (hyperthyroidism), a certain type of tumor (pheochromocytoma).

This drug may make you dizzy or drowsy. Alcohol or marijuana can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana.

To minimize dizziness and lightheadedness, get up slowly when rising from a seated or lying position.

Before having surgery, tell your doctor or dentist that you are taking this medication.

This drug may rarely make your blood sugar level rise, causing or worsening diabetes. Tell your doctor right away if you develop symptoms of high blood sugar such as increased thirst or frequent urination.

If you have diabetes, this medication may mask the fast/pounding heartbeat you would usually feel when your blood sugar level falls too low (hypoglycemia). Other symptoms of a low blood sugar level such as dizziness and sweating are unaffected by this drug.

Kidney function declines as you grow older. This medication is removed by the kidneys and liver. Therefore, elderly people may be at greater risk for side effects such as dizziness while using this drug.

This medication should be used only when clearly needed during pregnancy. It may harm an unborn baby. Discuss the risks and benefits with your doctor.

This drug passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.

Is it safe during pregnancy or breast-feeding?

There are no adequate studies in women for determining risk when using this Pindolol during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Pindolol. Pindolol is pregnancy risk category B according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk,
  • B=No risk in some studies,
  • C=There may be some risk,
  • D=Positive evidence of risk,
  • X=Contraindicated,
  • N=Unknown

Side effects

What side effects can occur from Pindolol?

Dizziness, drowsiness, weakness, and nausea may occur as your body adjusts to the medication. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

This drug may reduce blood flow to your hands and feet, causing them to feel cold. Smoking may worsen this effect. Avoid tobacco use and dress warmly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: new or worsening symptoms of heart failure (such as shortness of breath, swelling ankles/feet, unusual tiredness, unusual/sudden weight gain), bluish color of the fingers/toes/nails, hair loss (reversible), mental/mood changes (e.g., confusion, depression, memory problems), pain/cramps in the muscles/joints, numbness/tingling, decreased sexual ability, vision changes, slow/irregular/fast heartbeat, severe dizziness/fainting.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Pindolol?

Some products that may interact with this drug include: alpha-blockers (e.g., prazosin), arbutamine, other beta-blockers (e.g., atenolol), clonidine, epinephrine, fenoldopam, fingolimod, thioridazine, other drugs for high blood pressure (e.g., methyldopa, reserpine), drugs affecting liver enzymes that remove this medication from your body (e.g., amiodarone, chlorpromazine, St. John’s wort).

Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana, drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or antihistamines (such as cetirizine, diphenhydramine).

Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.

Some products have ingredients that could raise your heart rate or blood pressure. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen).

Pindolol may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Pindolol?

Pindolol may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Pindolol?

Pindolol may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using this Pindolol.

What is the dose of Pindolol for an adult?

Usual Adult Dose for Hypertension

Initial dose: 5 mg orally 2 times a day

Titration: The dose may be adjusted in increments of 10 mg per day every 3 to 4 weeks

Maximum dose: 60 mg per day

Comments:

-This drug may be taken with or without food.

-This drug may be given alone or in combination with other antihypertensive drugs.

-Antihypertensive response usually occurs within the first week of treatment.

-Maximal response may take 2 weeks or longer.

Use: For the management of hypertension as a single agent or concomitantly with other antihypertensive agents, particularly with a thiazide-type diuretic

Other Comments

Administration advice:

-This drug may be taken with or without food.

General:

-This drug may be given alone or in combination with other antihypertensive drugs.

-Antihypertensive response usually occurs within the first week of treatment.

-Maximal response may take 2 weeks or longer.

Monitoring:

-Both cardiac and thyroid function should be monitored in patients having, or suspected of developing, thyrotoxicosis.

What is the dose of Pindolol for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Pindolol available?

Pindolol is available in the following dosage forms and strengths:

  • Oral tablet,
  • Compounding powder.

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Pindolol, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

 

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: April 11, 2018 | Last Modified: April 11, 2018

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