Generic Name: Pepto-Bismol Brand Name(s): . Reviews:

Uses

What is Pepto-Bismol® (bismuth subsalicylate) used for?

Pepto-Bismol® is commonly used for relieving travelers’ diarrhea, diarrhea, and upset stomach.

Pepto-Bismol® may be prescribed for other uses; ask your doctor or pharmacist for more information.

How should I take Pepto-Bismol® (bismuth subsalicylate)?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Do not take more than 8 doses in one day (24 hours).

Shake the liquid medicine well just before you measure a dose. Measure the liquid with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

The chewable tablet must be chewed before you swallow it.

Bismuth subsalicylate can cause you to have a black or darkened tongue. This is a harmless side effect.

This medication can also cause unusual results with certain medical tests, thyroid scans, or stomach x-rays. Tell any doctor who treats you that you have recently taken bismuth subsalicylate.

How do I store Pepto-Bismol® (bismuth subsalicylate)?

Pepto-Bismol® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Pepto-Bismol® in the bathroom or the freezer. There may be different brands of Pepto-Bismol® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Pepto-Bismol® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Pepto-Bismol® (bismuth subsalicylate)?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of Pepto-Bismol® or other medications.
  • You have any other illnesses, disorders, or medical conditions.
  • You have diabetes, gout, arthritis, fever, mucus in the stool, inflammation of the stomach, Kawasaki syndrome, kidney problems, chickenpox, the flu, or joint problems (in children), or you are dehydrated.

Do not use if you have bleeding problems (e.g., hemophilia), active bleeding ulcer, black or bloody stools, or Von Willebrand disease.

This medication should not be given to a child or teenager who has a fever, especially if the child also has flu symptoms or chicken pox. Subsalicylate can cause a serious and sometimes fatal condition called Reye’s syndrome in children.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using Pepto-Bismol® during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Pepto-Bismol®. Pepto-Bismol® is pregnancy risk category N, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from Pepto-Bismol® (bismuth subsalicylate)?

Stop taking this medicine and call your doctor at once if you have:

  • Hearing loss or ringing in your ears
  • Diarrhea lasting longer than 2 days
  • Worsened stomach symptoms

Common side effects include:

  • Constipation
  • Dark colored stools
  • Black or darkened tongue

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Pepto-Bismol® (bismuth subsalicylate)?

Pepto-Bismol® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products that may interact with this drug are:

  • A blood thinner such as warfarin (Coumadin, Jantoven)
  • Insulin or oral diabetes medications
  • Probenecid (Benemid)
  • An antibiotic such as doxycycline (Doryx, Oracea, Periostat, Vibramycin), minocycline (Dynacin, Minocin, Solodyn), or tetracycline (Ala-Tet, Brodspec, Panmycin, Sumycin, Tetracap)
  • Medication used to prevent blood clots, such as alteplase (Activase), tenecteplase (TNKase), urokinase (Abbokinase)
  • Other salicylates such as aspirin, Nuprin Backache Caplet, Kaopectate, KneeRelief, Pamprin Cramp Formula, Pepto-Bismol, Tricosal, Trilisate, and others

Does food or alcohol interact with Pepto-Bismol® (bismuth subsalicylate)?

Pepto-Bismol® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Pepto-Bismol® (bismuth subsalicylate)?

Pepto-Bismol® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Health conditions that may interact with this drug are:

  • Fever
  • Mucus in your stools
  • Diabetes
  • Arthritis
  • Gout

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Pepto-Bismol® (bismuth subsalicylate).

What is the dose of Pepto-Bismol® (bismuth subsalicylate) for an adult?

Usual Adult Dose for Dyspepsia

524 mg orally every 30 to 60 minutes as needed not to exceed 8 doses in any 24-hour period.

Alternatively, 1048 mg to 1050 mg may be given orally every hour not to exceed 4 doses in any 24-hour period.

Usual Adult Dose for Traveler’s Diarrhea

524 mg orally every 30 to 60 minutes as needed not to exceed 8 doses in any 24-hour period.

Alternatively, 1048 mg to 1050 mg may be given orally every hour not to exceed 4 doses in any 24-hour period.

Usual Adult Dose for Diarrhea

524 mg orally every 30 to 60 minutes as needed not to exceed 8 doses in any 24-hour period.

Alternatively, 1048 mg to 1050 mg may be given orally every hour not to exceed 4 doses in any 24-hour period

What is the dose of Pepto-Bismol® (bismuth subsalicylate) for a child?

Usual Pediatric Dose for Diarrhea

Non-specific diarrhea:

<3 years: use with caution

3 to 6 years: 87 mg every 30 minutes to 1 hour as needed.

6 to 9 years: 175 mg every 30 minutes to 1 hour as needed.

9 to 12 years: 262 mg every 30 minutes to 1 hour as needed.

Usual Pediatric Dose for Diarrhea – Chronic

Chronic Infantile Diarrhea:

2 to 24 months: 44 mg every 4 hours

24 to 48 months: 87 mg every 4 hours

48 to 70 months: 175 mg every 4 hours

How is Pepto-Bismol® (bismuth subsalicylate) available?

Pepto-Bismol® is available in the following dosage forms and strengths:

  • Tablet

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Pepto-Bismol®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: September 13, 2017 | Last Modified: September 13, 2017

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