By Medically reviewed by hellodoktor

Generic Name: Oxycontin Brand Name(s): Generics only. No brands available.


What is Oxycontin® (oxycodone) used for?

Oxycontin® is an opioid pain medication. An opioid is sometimes called a narcotic.

Oxycontin® is used to treat moderate to severe pain that is expected to last for an extended period of time. Oxycontin® is used for around-the-clock treatment of pain. It is not to be used on an “as-needed” basis for pain.

Oxycontin® may also be used for purposes not listed in this medication guide.

How should I take Oxycontin® (oxycodone)?

Take Oxycontin® exactly as prescribed. Follow all directions on your prescription label. Oxycontin® can slow or stop your breathing, especially when you start using this medicine or whenever your dose is changed. Never take Oxycontin® in larger amounts, or for longer than prescribed. Tell your doctor if the medicine seems to stop working as well in relieving your pain.

Oxycontin® may be habit-forming. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. Misuse of narcotic medicine can cause addiction, overdose, or death, especially in a child or other person using the medicine without a prescription. Selling or giving away Oxycontin® is against the law.

Stop taking all other around-the-clock narcotic pain medicines when you start taking extended-release Oxycontin®.

Take with food.

Do not crush, break, or open an extended-release tablet. Swallow it whole to avoid exposure to a potentially fatal dose.

You should not stop using oxycodone suddenly. Follow your doctor’s instructions about tapering your dose.

Never crush or break a tablet to inhale the powder or mix it into a liquid to inject the drug into your vein. This can cause in death.

Keep track of the amount of medicine used from each new bottle. Oxycodone is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Do not keep leftover Oxycontin® tablets. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, flush any unused tablets down the toilet.

How do I store Oxycontin® (oxycodone)?

Oxycontin® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Oxycontin® in the bathroom or the freezer. There may be different brands of Oxycontin® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Oxycontin® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Oxycontin® (oxycodone)?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of Oxycontin® or other medications.
  • You have any other illnesses, disorders, or medical conditions.
  • You use a sedative like Valium (diazepam, alprazolam, lorazepam, Ativan, Klonopin, Restoril, Tranxene, Versed, Xanax, and others).

You should not use Oxycontin® if you have:

  • Severe asthma or breathing problems
  • A blockage in your stomach or intestines

You should not use Oxycontin® unless you are already using a similar opioid medicine and are tolerant to it.

Oxycontin® should not be given to a child younger than 11 years old.

If you use Oxycontin® while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks.

Long-term use of opioid medication may affect fertility (ability to have children) in men or women. It is not known whether opioid effects on fertility are permanent.

Do not breastfeed. Oxycodone can pass into breast milk and may cause drowsiness or breathing problems in a nursing baby.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using Oxycontin® during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Oxycontin®. Oxycontin® is pregnancy risk category N, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from Oxycontin® (oxycodone)?

Common side effects may include:

  • Drowsiness
  • Headache
  • Dizziness
  • Tired feeling
  • Constipation
  • Stomach pain
  • Nausea
  • Vomiting
  • Loss of appetite
  • Dry mouth
  • Mild itching

Call your doctor at once if you have:

  • Shallow breathing, slow heartbeats
  • Confusion
  • Severe drowsiness
  • Seizure (convulsions)
  • Severe constipation
  • Missed menstrual periods
  • Impotence, sexual problems, loss of interest in sex
  • A light-headed feeling, like you might pass out
  • Low cortisol levels – nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness

Seek medical attention right away if you have symptoms of serotonin syndrome, such as agitation, confusion, fever, sweating, fast heart rate, chest pain, feeling short of breath, muscle stiffness, trouble walking, or feeling faint.

Get emergency medical help if you have signs of an allergic reaction to Oxycontin®: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Like other narcotic medicines, oxycodone can slow your breathing. Death may occur if breathing becomes too weak.

A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, pinpoint pupils, or if you are hard to wake up.

Serious side effects may be more likely in older adults and those who are malnourished or debilitated.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with Oxycontin® (oxycodone)?

Oxycontin® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products that may interact with this drug are:

  • Other narcotic medications – opioid pain medicine or prescription cough medicine
  • Drugs that make you sleepy or slow your breathing – a sleeping pill, muscle relaxer, sedative, tranquilizer, or antipsychotic medicine
  • Drugs that affect serotonin levels in your body – medicine for depression, Parkinson’s disease, migraine headaches, serious infections, or prevention of nausea and vomiting

Does food or alcohol interact with Oxycontin® (oxycodone)?

Oxycontin® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Oxycontin® (oxycodone)?

Oxycontin® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Health conditions that may interact with this drug are:

  • A history of head injury, brain tumor, or seizures
  • A history of drug abuse, alcohol addiction, or mental illness
  • Urination problems
  • Liver or kidney disease
  • Problems with your gallbladder, pancreas, or thyroid


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Oxycontin® (oxycodone).

What is the dose of Oxycontin® (oxycodone) for an adult?

Usual Adult Dose for Pain:


Controlled Release (CR): 10 mg orally every 12 hours.


CR: 20 mg to 640 mg per day in patients with cancer pain. The average total daily dose is approximately 105 mg per day. Cancer patients with severe pain may require “as needed” rescue doses of the immediate-release form of oxycodone to supplement the controlled-release form.

Usual Geriatric Dose for Pain:


Immediate Release (IR): 2.5 mg orally every 6 hours.


CR: 20 mg to 640 mg per day in patients with cancer pain. The average total daily dose is approximately 105 mg per day. Cancer patients with severe pain may require “as needed” rescue doses of the immediate-release form of oxycodone to supplement the controlled-release form.

What is the dose of Oxycontin® (oxycodone) for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Oxycontin® (oxycodone) available?

Oxycontin® is available in the following dosage forms and strengths:

  • Tablet, film coated, extended release: oxycodone hydrochloride 80mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Oxycontin®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

msBahasa Malaysia

Review Date: July 14, 2017 | Last Modified: September 13, 2019