By Medically reviewed by hellodoktor

Generic Name: Opedroxil Brand Name(s): Generics only. No brands available.


What is opedroxil (cephadroxil) used for?

Opedroxil is commonly used for treating many different types of infections, such as urinary tract infections, skin and skin structure infections, pharyngitis or tonsillitis, which are caused by bacteria. Opedroxil only works against bacteria; it does not treat viral infections (e.g., the common cold).

It can be used for other purposes, ask your doctor for more information.

How should I take opedroxil (cephadroxil)?

Take opedroxil by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.

To clear up your infection completely, take opedroxil for the full course of treatment. Keep taking it even if you feel better in a few days.

Ask your health care provider any questions you may have about how to use cefadroxil.

How do I store opedroxil (cephadroxil)?

Opedroxil is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store opedroxil in the bathroom or the freezer. There may be different brands of opedroxil that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush opedroxil down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using opedroxil (cephadroxil)?

Before using this drug, tell your doctor if:

  • You are allergic to any ingredient in opedroxil or any other cephalosporin (e.g., cephalexin).
  • You are pregnant, planning to become pregnant, or are breastfeeding.
  • You are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement.
  • You have allergies to medicines, foods, or other substances.

Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.

Be sure to use opedroxil for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.

Long-term or repeated use of opedroxil may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.

Diabetes patients: opedroxil may cause the results of some tests for urine glucose to be wrong. Ask your doctor before you change your diet or the dose of your diabetes medicine.

Opedroxil may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking opedroxil.

Use opedroxil with caution in the elderly; they may be more sensitive to the effects of opedroxil.

Use opedroxil with extreme caution in children younger than 10 years old who have diarrhea or an infection of the stomach or bowel.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using opedroxil during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking opedroxil. Opedroxil is pregnancy risk category B, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from opedroxil (cephadroxil)?

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most common side effects persist or become bothersome:

  • Diarrhea
  • Nausea
  • Stomach upset
  • Vomiting

Seek medical attention right away if any of these severe side effects occur:

  • Rash
  • Hives
  • Itching
  • Difficulty breathing
  • Tightness in the chest
  • Swelling of the mouth, face, lips, or tongue
  • Bloody diarrhea
  • Dark urine
  • Decreased urination
  • Fever, chills, or sore throat
  • Joint pain
  • Red, swollen, or blistered skin
  • Seizures
  • Severe diarrhea
  • Stomach pain or cramps
  • Unusual bruising or bleeding
  • Unusual tiredness or weakness
  • Vaginal itching, odor, or discharge
  • Yellowing of the skin or eyes

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with opedroxil (cephadroxil)?

Opedroxil may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with opedroxil (cephadroxil)?

Opedroxil may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with opedroxil (cephadroxil)?

Opedroxil may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

These health conditions may include:

  • A blood clotting disorder
  • Kidney problems
  • Stomach or bowel problems (e.g., inflammation)
  • A severe allergic reaction (e.g., a severe rash, hives, breathing difficulties, or dizziness) to a penicillin antibiotic (e.g., amoxicillin) or other beta-lactam antibiotic (e.g., imipenem).


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using opedroxil (cephadroxil).

What is the dose of opedroxil (cephadroxil) for an adult?

Uncomplicated UTI:

The recommended dose is 1–2g once daily or in 2 divided doses.

Complicated UTI:

The recommended dose is 2g/day in 2 divided doses.

Skin and skin structure infections:

The recommended dose is 1g once daily or in 2 divided doses.


The recommended dose is 1g once daily or in 2 divided doses for 10 days.

Renal dysfunction (CrCl <50mL/min):

The recommended dose is 1g loading dose, then 500mg at increased dosing intervals. Continue for 3 days after symptoms improve.

What is the dose of opedroxil (cephadroxil) for a child?

UTI, skin and skin structure infections:

The recommended dose is 30mg/kg/day in 2 divided doses every 12 hours.

Pharyngitis/tonsillitis, impetigo:

The recommended dose is 30mg/kg once daily or in 2 divided doses for 10 days.

Renal dysfunction:

Reduce dose. Continue for 3 days after symptoms improve.

How is opedroxil (cephadroxil) available?

Opedroxil is available in the following dosage forms and strengths:

  • Cefadroxil suspension 250mg/5mL

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of opedroxil, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

msBahasa Malaysia

Review Date: April 14, 2017 | Last Modified: September 13, 2019

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