By Medically reviewed by hellodoktor

Generic Name: Ocufen Brand Name(s): Generics only. No brands available.


What is Ocufen® (flurbiprofen sodium) used for?

Ocufen® is a nonsteroidal anti-inflammatory drug (NSAID) eye drop. It works by blocking certain substance that causes inflammation (redness, swelling, and irritation).

Ocufen® is commonly used for certain types of eye surgery. It may also be used for other conditions as determined by your doctor.

How should I take Ocufen® (flurbiprofen sodium)?

Use Ocufen® drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

To use Ocufen®, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eye for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.

To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including your eye. Keep the container tightly closed.

Do not administer Ocufen® drops while wearing contact lenses. Talk to your doctor about the proper use of Ocufen® if you usually wear contact lenses.

If you will be using Ocufen® drops in both eyes, do not use the same bottle for both eyes. Doing so may increase the risk of passing an infection from one eye to the other.

How do I store Ocufen® (flurbiprofen sodium)?

Ocufen® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Ocufen® in the bathroom or the freezer. There may be different brands of Ocufen® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Ocufen® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Ocufen® (flurbiprofen sodium)?

Before using this drug, tell your doctor if:

  • You are allergic to any ingredient in Ocufen®.
  • You have had an allergic reaction (e.g., severe rash, hives, difficulty breathing, dizziness) to aspirin or any medicine containing aspirin or a NSAID (e.g., ibuprofen).
  • You are using a corticosteroid eye drop (e.g., prednisolone) or other medicines in the eye.
  • You have had complicated eye surgery or have had repeated eye surgeries within a short period of time.

Do not exceed the recommended dose or take Ocufen® for longer than prescribed without checking with your doctor.

Ocufen® should be used with extreme caution in children; safety and efficacy in children have not been confirmed.

Is it safe during pregnancy or breastfeeding?

There isn’t enough information about the safety of using Ocufen® during pregnancy and breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Ocufen®.

Side effects

What side effects can occur from Ocufen® (flurbiprofen sodium)?

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most common side effects persist or become bothersome:

  • Sensitivity of the eye(s) to light
  • Temporary burning, irritation, or stinging of the eye

Seek medical attention right away if any of these severe side effects occur:

  • Severe allergic reactions including rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue
  • Bleeding of the eye
  • Severe or persistent burning, irritation, itching, redness, stinging, or swelling of the eye
  • Vision changes

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with Ocufen® (flurbiprofen sodium)?

Ocufen® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

These products that interact with this drug including:

  • Anticoagulants (e.g., warfarin), aspirin, or heparin, because the risk of bleeding may be increased.
  • Acetylcholine or carbachol, because their effectiveness may be decreased by Ocufen®.

Does food or alcohol interact with Ocufen® (flurbiprofen sodium)?

Ocufen® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Ocufen® (flurbiprofen sodium)?

Ocufen® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Tell your doctor or pharmacist if you have any medical conditions, especially if any of the followings apply to you:


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Ocufen® (flurbiprofen sodium).

What is the dose of Ocufen® (flurbiprofen sodium) for an adult?

Dose before surgery

The usual dose is 1 drop in the eye(s) undergoing surgery, every half hour starting 2 hours before the operation or laser surgery (4 drops in total per eye being treated).

The final drop should be given at least 30 minutes before surgery.

Dose after surgery

24 hours after laser surgery, the usual dose is 1 drop, 4 times a day for 1 week.

24 hours after eye surgery, the usual dose is 1 drop, 4 times a day for 2 to 3 weeks.

What is the dose of Ocufen® (flurbiprofen sodium) for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Ocufen® (flurbiprofen sodium) available?

Ocufen® is available in the following dosage forms and strengths:

  • Ocufen® 0.4ml vial
  • Flurbiprofen sodium 0.03%

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Ocufen®, contact your doctor immediately.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Review Date: March 18, 2017 | Last Modified: September 13, 2019