By Medically reviewed by hellodoktor

Generic Name: Novobedouze Brand Name(s): Generics only. No brands available.


What is novobedouze (hydroxocobalamin acetate) used for?

Hydroxocobalamin is a vitamin. It works by increasing levels of vitamin B12 in conditions needed.

Novobedouze is commonly used for treating anemia and vitamin B12 deficiency due to a number of conditions, including poor diet, and for the Schilling test.

How should I take novobedouze (hydroxocobalamin acetate)?

Novobedouze is usually administered as an injection at your doctor’s office, hospital, or clinic. If you are using novobedouze at home, carefully follow the injection procedures taught to you by your health care provider.

If novobedouze contains particles or is discolored, or if the vial is cracked or damaged in any way, do not use it.

Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor or pharmacist to explain local regulations for proper disposal.

Ask your health care provider any questions you may have about how to use novobedouze.

How do I store novobedouze (hydroxocobalamin acetate)?

Novobedouze is usually handled and stored by a health care provider. If you are using novobedouze at home, store novobedouze as directed by your pharmacist or health care provider. Keep novobedouze out of the reach of children and away from pets.

Precautions & warnings

What should I know before using novobedouze (hydroxocobalamin acetate)?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of novobedouze or other medications.
  • You have any other illnesses, disorders, or medical conditions.

Do not take large doses of vitamins (megadoses or megavitamin therapy) unless directed to by your doctor.

Is it safe during pregnancy or breastfeeding?

There isn’t enough information about the safety of using this medication during pregnancy and breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking this medication.

Side effects

What side effects can occur from novobedouze (hydroxocobalamin acetate)?

Seek medical attention right away if any of these severe side effects occur:

  • Rash
  • Hives
  • Difficulty breathing
  • Tightness in the chest
  • Swelling of the mouth, face, lips, or tongue
  • Changes in blood pressure
  • Diarrhea
  • Fainting
  • Flushing
  • Itching
  • Leg pain
  • Pain or redness at the injection site
  • Swelling

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with novobedouze (hydroxocobalamin acetate)?

Novobedouze may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Especially if you are taking omeprazole because the effectiveness of hydroxocobalamin may be decreased.

Does food or alcohol interact with novobedouze (hydroxocobalamin acetate)?

Novobedouze may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with novobedouze (hydroxocobalamin acetate)?

Novobedouze may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using novobedouze (hydroxocobalamin acetate).

What is the dose of novobedouze (hydroxocobalamin acetate) for an adult?

Treatment of Vitamin B12 Deficiency

Thirty mcg daily for 5 to 10 days followed by 100 to 200 mcg monthly injected intramuscularly.

If the patient is critically ill, or has neurologic disease, an infectious disease or hyperthyroidism, considerably higher doses may be indicated.

However, current data indicate that the optimum obtainable neurologic response may be expected with a dosage of vitamin B12 sufficient to produce good hematologic response.

Patients who have normal intestinal absorption may be treated with an oral therapeutic multivitamin preparation, containing 15 mcg vitamin B12 daily.

Schilling Test

The flushing dose is 1000 mcg.

What is the dose of novobedouze (hydroxocobalamin acetate) for a child?

Children may be given a total of 1 to 5 mg over a period of 2 or more weeks in doses of 100 mcg, then 30 to 50 mcg every 4 weeks for maintenance.

How is novobedouze (hydroxocobalamin acetate) available?

Novobedouze is available in the following dosage forms and strengths:

  • Novobedouze 10mg/2mL solution injection

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of novobedouze, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

msBahasa Malaysia

Review Date: April 15, 2017 | Last Modified: September 12, 2019

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