Generic Name: Norco Brand Name(s): Generics only. No brands available.

Uses

What is Norco® (acetaminophen and hydrocodone) used for?

Norco® is commonly used relieve moderate to moderately severe pain. It contains an opioid (narcotic) pain reliever (hydrocodone) and a non-opioid pain reliever (acetaminophen).

How should I take Norco® (acetaminophen and hydrocodone)?

Take this medication by mouth as exactly prescribed by your doctor. You may take this drug with or without food. If you have nausea, it may help to take this drug with food.

If you are using a liquid form of this medication, use a medication measuring device to carefully measure the prescribed dose.

Hydrocodone in Norco® may be addictive, even at regular doses. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. Misuse of narcotic medicine can cause addiction, overdose, or death, especially in a child or other person using the medicine without a prescription. Selling or distributing Norco is illegal.

Do not stop using this medicine suddenly after long-term use, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using Norco®.

How do I store Norco® (acetaminophen and hydrocodone)?

Norco® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Norco® in the bathroom or the freezer. There may be different brands of Norco® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Norco® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Norco® (acetaminophen and hydrocodone)?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of Norco® or other medications.
  • You have any other illnesses, disorders, or medical conditions.

You should not use Norco® if you are allergic to acetaminophen (Tylenol) or hydrocodone, or if you have recently used alcohol, sedatives, tranquilizers, or other narcotic medications.

Do not use Norco® if you have taken a MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Some medicines can interact with hydrocodone and cause a serious condition called serotonin syndrome. Be sure your doctor knows if you also take medicine for depression, mental illness, Parkinson’s disease, migraine headaches, serious infections, or prevention of nausea and vomiting. Ask your doctor before making any changes in how or when you take your medications.

Norco® is more likely to cause breathing problems in older adults and people who are severely ill, malnourished, or otherwise debilitated.

If you use narcotic medicine while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks. Tell your doctor if you are pregnant or plan to become pregnant.

Acetaminophen and hydrocodone can pass into breast milk and may harm a nursing baby. You should not breast-feed while using Norco.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using this medication during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking this medication. This medication is pregnancy risk category C according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from Norco® (acetaminophen and hydrocodone)?

Common side effects include:

  • Drowsiness
  • Headache
  • Dizziness
  • Lightheadedness
  • Upset stomach
  • Constipation
  • Blurred vision
  • Dry mouth

Call your doctor at once if you have:

  • Shallow breathing, slow heartbeat
  • A light-headed feeling, like you might pass out
  • Confusion, unusual thoughts or behavior
  • Seizure (convulsions)
  • Easy bruising or bleeding
  • Infertility, missed menstrual periods
  • Impotence, sexual problems, loss of interest in sex
  • Liver problems – nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes)
  • Low cortisol levels – nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness

In rare cases, acetaminophen may cause a severe skin reaction that can be fatal. This could occur even if you have taken acetaminophen in the past and had no reaction. Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling. If you have this type of reaction, you should never again take any medicine that contains acetaminophen.

Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.

Get emergency medical help if you have signs of an allergic reaction to Norco®: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Norco® (acetaminophen and hydrocodone)?

Norco® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products that may interact with this drug are:

  • Other narcotic medications – opioid pain medicine or prescription cough medicine
  • Drugs that make you sleepy or slow your breathing – a sleeping pill, muscle relaxer, sedative, tranquilizer, or antipsychotic medicine
  • Drugs that affect serotonin levels in your body – medicine for depression, Parkinson’s disease, migraine headaches, serious infections, or prevention of nausea and vomiting

Does food or alcohol interact with Norco® (acetaminophen and hydrocodone)?

Norco® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Norco® (acetaminophen and hydrocodone)?

Norco® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Health conditions that may interact with this drug are:

  • Alcoholism
  • Liver Disease
  • Impaired GI Motility
  • Infectious Diarrhea
  • Liver Disease
  • Prematurity
  • Renal Dysfunction
  • Acute Alcohol Intoxication
  • Drug Dependence
  • Hypotension
  • Intracranial Pressure
  • Respiratory Depression
  • PKU
  • Adrenal Insufficiency
  • Biliary Spasm
  • Hypothyroidism
  • Seizure Disorders
  • Urinary Retention
  • Arrhythmias

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using this medication.

What is the dose of Norco® (acetaminophen and hydrocodone) for an adult?

Recommended dose is 1 to 2 tablets orally every 4 to 6 hours as needed.

Maximum dose is 8 tablets daily.

What is the dose of Norco® (acetaminophen and hydrocodone) for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Norco® (acetaminophen and hydrocodone) available?

Norco® is available in the following dosage forms and strengths:

  • Tablet: hydrocodone bitartrate 5mg, acetaminophen 325mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Norco®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: July 23, 2017 | Last Modified: July 23, 2017

Want to live your best life?
Get the Hello Doktor Daily newsletter for health tips, wellness updates and more.