Noradrenaline (norepinephrine)

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Generic Name: Noradrenaline (norepinephrine) Brand Name(s): Generics only. No brands available.

Uses

What is noradrenaline (norepinephrine) used for?

Noradrenaline is commonly used for treating low blood pressure. It may also be used for other conditions as determined by your doctor.

How should I take noradrenaline (norepinephrine)?

Norepinephrine is given via a drip into a vein (intravenous infusion)

How should I store noradrenaline (norepinephrine)?

Noradrenaline is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store noradrenaline in the bathroom or the freezer. There may be different brands of noradrenaline that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush noradrenaline down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using noradrenaline (norepinephrine)?

Before using this drug, tell your doctor:

  • If you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement.
  • If you have allergies to medicines, foods, or other substances.
  • You are allergic to any ingredient in norepinephrine.
  • You take norepinephrine before you receive any medical or dental care, emergency care, or surgery.
  • You are elderly.

Is it safe during pregnancy or breastfeeding?

If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using norepinephrine while you are pregnant. Norepinephrine may be found in breast milk. If you are or will be breastfeeding while you use norepinephrine, check with your doctor. Discuss any possible risks to your baby.

Side effects

What side effects can occur from noradrenaline (norepinephrine)?

Some side effects can occur when using this drug, such as:

  • Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; wheezing)
  • Anxiety
  • Change in skin color (e.g., on the lips, nail beds, fingers, or toes)
  • Fast, slow, or irregular heartbeat
  • Severe or persistent dizziness or headache
  • Redness
  • Burning
  • Pain
  • Swelling
  • Leaking of fluid

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with noradrenaline (norepinephrine)?

Noradrenaline may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Some medicines may interact with norepinephrine. Tell your health care provider if you are taking any other medicines, especially any of the following:

Does food or alcohol interact with noradrenaline (norepinephrine)?

Noradrenaline may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with noradrenaline (norepinephrine)?

Noradrenaline may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

These health conditions are:

  • Blood vessel problems
  • Blood clots
  • Thyroid problems

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using noradrenaline (norepinephrine).

What is the dose of noradrenaline (norepinephrine) for an adult?

Average dosage: 

Add a 4 ml ampul (4 mg) of norepinephrine to 1,000 ml of a 5 percent dextrose containing solution. Each ml of this dilution contains 4 mcg of the base of norepinephrine.

What is the dose of noradrenaline (norepinephrine) for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is noradrenaline (norepinephrine) available?

Noradrenaline is available in the following dosage forms and strengths:

  • Intravenous solution 2mg/ ml.

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

Overdosage with norepinephrine may result in headache, severe hypertension, reflex bradycardia, marked increase in peripheral resistance, and decreased cardiac output. In case of accidental overdosage, as evidenced by excessive blood pressure elevation, discontinue norepinephrine until the condition of the patient stabilizes.

What should I do if I miss a dose?

If you miss a dose of noradrenaline, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Review Date: January 13, 2017 | Last Modified: January 13, 2017

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