Generic Name: Nizoral tablet Brand Name(s): Generics only. No brands available.

Uses

What is Nizoral® (ketoconazole) used for?

Nizoral® is commonly used for treating infections caused by fungus.

Ketoconazole is not used in treating fungal infections of the fingernails or toenails, prostate cancer or Cushing syndrome.

This medicine should be used only when you cannot use other antifungal medications.

Nizoral® can cause serious harm to your liver that may result in liver transplant or cause death.

How should I take Nizoral® (ketoconazole)?

Take Nizoral® exactly as it was prescribed for you. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Do not share this medicine with another person, even if they have the same symptoms that you have.

Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antifungal medicine. Nizoral® will not treat a viral infection such as the common cold or flu.

How do I store Nizoral® (ketoconazole)?

Nizoral® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Nizoral® in the bathroom or the freezer. There may be different brands of Nizoral® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Nizoral® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Nizoral® (ketoconazole)?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of Nizoral® or other medications.
  • You have any other illnesses, disorders, or medical conditions.

While using Nizoral®, you may need frequent blood tests to check your liver function.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using Nizoral® during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Nizoral®. Nizoral® is pregnancy risk category C, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from Nizoral® (ketoconazole)?

Common side effects may include:

  • Mild nausea
  • Stomach pain
  • Diarrhea
  • Headache

Call your doctor at once if you have:

  • Headache with chest pain
  • Severe dizziness
  • Fainting
  • Fast or pounding heartbeats
  • Unusual weakness or tired feeling
  • Nausea
  • Vomiting
  • Upper stomach pain
  • Itching
  • Tired feeling
  • Loss of appetite
  • Dark urine
  • Clay-colored stools
  • Jaundice (yellowing of the skin or eyes)

Get emergency medical help if you have any signs of an allergic reaction such as hives; fever; difficulty breathing, chest pain; swelling of your face, lips, tongue, or throat.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Nizoral® (ketoconazole)?

Nizoral® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Some products that may interact with this drug, including:

  • Alprazolam, midazolam, or triazolam
  • Cisapride or pimozide
  • Dihydroergotamine or ergotamine
  • Disopyramide, dofetilide, dronedarone, eplerenone, nisoldipine, quinidine, or ranolazine
  • Lovastatin or simvastatin
  • Methadone

Does food or alcohol interact with Nizoral® (ketoconazole)?

Nizoral® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Nizoral® (ketoconazole)?

Nizoral® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

These health conditions are:

  • Any history of liver problems
  • Problems with your adrenal gland
  • A family history of long QT syndrome

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Nizoral® (ketoconazole).

What is the dose of Nizoral® (ketoconazole) for an adult?

Fungal Infections:

The recommended dose is 200-400 mg/day PO.

Cushing Syndrome (Off-label):

Used off-label to inhibit steroidogenesis in patients with Cushing syndrome: The recommended dose is 600-800 mg/day PO.

Recurrent Tinea Versicolor (Off-label): The recommended dose is 400 mg PO monthly.

What is the dose of Nizoral® (ketoconazole) for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Nizoral® (ketoconazole) available?

Nizoral® is available in the following dosage forms and strengths:

  • Nizoral® 20mg tablet

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Nizoral®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: June 1, 2017 | Last Modified: June 1, 2017

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