What is Neoamiyu® (amino acids) used for?
Neoamiyu® is indicated for the treatment of hepatic encephalopathy in patients with cirrhosis or hepatitis.
It provides nutritional support for these patients, who require parenteral nutrition and are intolerant of general purpose amino acid injections, which are contraindicated in patients with hepatic coma.
How should I take Neoamiyu® (amino acids)?
Neoamiyu® is given through a needle placed in one of your veins by your doctor.
How do I store Neoamiyu® (amino acids)?
Neoamiyu® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Neoamiyu® in the bathroom or the freezer. There may be different brands of Neoamiyu® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.
You should not flush Neoamiyu® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.
Precautions & warnings
What should I know before using Neoamiyu® (amino acids)?
Before taking Neoamiyu®, tell your doctor if:
- You are allergic to any ingredient in Neoamiyu®.
- You are pregnant, planning to become pregnant, or are breastfeeding.
- You are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement.
- You have allergies to medicines, foods, or other substances.
Significant deviations from normal concentrations may require the use of additional electrolyte supplements.
Strongly hypertonic nutrient solutions should be administered through an indwelling intravenous catheter with the tip located in the superior vena cava.
Special care must be taken when giving hypertonic dextrose to a diabetic or pre-diabetic patient.
To prevent severe hyperglycemia in such patients, insulin may be required.
Peripheral intravenous administration of this medicine requires appropriate dilution and provision of adequate calories. Care should be taken to assure proper placement of the needle within the lumen of the vein.
The venipuncture site should be inspected frequently for signs of infiltration. If venous thrombosis or phlebitis occurs, discontinue infusions or change infusion site and initiate appropriate treatment.
Care should be taken to avoid circulatory overload, particularly in patients with cardiac insufficiency.
In patients with myocardial infarct, infusion of amino acids should always be accompanied by dextrose since in anoxia, free fatty acids cannot be utilized by the myocardium and energy must be produced anaerobically from glycogen or glucose.
Infusion of this medicine may not affect the clinical course of patients with fulminant hepatitis who have a poor prognosis and are generally unresponsive to treatment. It has been shown that the abnormal plasma amino acid pattern in fulminant hepatitis differs from that in chronic liver disease.
Extraordinary electrolyte losses such as may occur during protracted nasogastric suction, vomiting, diarrhea, or gastrointestinal fistula drainage may necessitate additional electrolyte supplementation.
Administration of glucose at a rate exceeding the patient’s utilization rate may lead to hyperglycemia, coma, and death.
Metabolic acidosis can be prevented or readily controlled by adding a portion of the cations in the electrolyte mixture as acetate salts and in the case of hyperchloremic acidosis, by keeping the total chloride content of the infusate to a minimum.
To minimize the risk of possible incompatibilities arising from mixing this solution with other additives that may be prescribed, the final infusate should be inspected for cloudiness or precipitation immediately after mixing, prior to administration, and periodically during administration.
Is it safe during pregnancy or breastfeeding?
There isn’t enough information about the safety of using Neoamiyu® during pregnancy and breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Neoamiyu®.
What side effects can occur from Neoamiyu® (amino acids)?
Some side effects may occur during using Neoamiyu®:
- Water weight gain
- Increase the level of blood urea nitrogen
- Dilutional hyponatremia
Reactions which may occur because of the solution or the technique of administration include febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation, and hypervolemia.
Symptoms may result from an excess or deficit of one or more of the ions present in the solution; therefore, frequent monitoring of electrolyte levels is essential.
If an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate therapeutic countermeasures and save the remainder of the fluid for examination if deemed necessary.
Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.
What drugs may interact with Neoamiyu® (amino acids)?
Neoamiyu® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.
Does food or alcohol interact with Neoamiyu® (amino acids)?
Neoamiyu® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.
What health conditions may interact with Neoamiyu® (amino acids)?
Neoamiyu® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.
The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Neoamiyu® (amino acids).
What is the dose of Neoamiyu® (amino acids) for an adult?
Acute & chronic renal insufficiency w/o dialysis – Patient 70 kg
The recommended dose is 0.5 g amino acid/kg body with or 500 mL/day.
Chronic renal insufficiency under dialysis
The recommended dose is 1 g amino acid/kg body with or 1,000 mL/day.
Max dose is 1.5 g/kg body with or 1,500 mL/day.
Infusion rate <20 drops/min.
What is the dose of Neoamiyu® (amino acids) for a child?
The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.
How is Neoamiyu® (amino acids) available?
Neoamiyu® is available in the following dosage forms and strengths:
- Injection 200ml
What should I do in case of an emergency or overdose?
In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.
What should I do if I miss a dose?
If you miss a dose of Neoamiyu®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.
Hello Health Group does not provide medical advice, diagnosis or treatment.
Review Date: April 14, 2017 | Last Modified: September 13, 2019
Neoamiyu®. https://www.epharmapedia.com/medicine/profile/201157/Neoamiyu.html?lang=en&tab=druginfo. Accessed December 19, 2016
Neoamiyu®. http://www.ndrugs.com/?s=Neoamiyu&t=dosage. Accessed December 19, 2016