What is Naphazoline used for?
Naphazoline is a decongestant used to relieve redness, puffiness, and itchy/watering eyes due to colds, allergies, or eye irritations (smog, swimming, or wearing contact lenses). It is known as a sympathomimetic (alpha receptor agonist) that works in the eye to decrease congestion.
Some brands of naphazoline eye drops also contain other ingredients. Lubricants (such as glycerin, hypromellose, or polyethylene glycol 300) help protect the eyes from more irritation. Zinc sulfate, an astringent, helps reduce redness and irritation.
How should I take Naphazoline?
To apply eye drops, wash your hands first. To avoid contamination, do not touch the dropper tip or let it touch your eye or any other surface.
Remove contact lenses before applying the eye drops. Wait at least 10 minutes after using this medication before inserting contact lenses.
Before using, check this product visually. Do not use if the liquid has changed color or is cloudy. Use in affected eye(s) as directed.
Tilt your head back, look upward, and pull down the lower eyelid to make a pouch. Hold the dropper directly over the eye and place 1 drop into the pouch. Look downward and gently close your eyes for 1 to 2 minutes. Place one finger at the corner of the eye near the nose and apply gentle pressure. This will prevent the medication from draining away from the eye. Try not to blink and do not rub the eye. Repeat these steps if your dose is for more than 1 drop and for the other eye if so directed.
Do not rinse the dropper. Replace the dropper cap tightly after each use.
If you are using another kind of eye medication (e.g., drops or ointments), wait at least 5 minutes before applying other medications. Use eye drops before eye ointments to allow the eye drops to enter the eye.
Overuse of this type of medication may result in increased eye redness (rebound hyperemia). Tell your doctor if this occurs or if your condition persists or worsens after 48 hours.
How do I store Naphazoline?
Naphazoline is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Naphazoline in the bathroom or the freezer. There may be different brands of Naphazoline that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.
You should not flush Naphazoline down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.
Precautions & warnings
What should I know before using Naphazoline?
Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (e.g., high blood pressure), glaucoma, diabetes, eye infection/injury, overactive thyroid (hyperthyroidism).
After you apply this drug, your vision may become temporarily blurred. This drug may also make you dizzy or drowsy. Alcohol or marijuana can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana.
Caution is advised when using this drug in children because they may be more sensitive to its effects, especially severe drowsiness and severely decreased body temperature.
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.
Is it safe during pregnancy or breast-feeding?
There are no adequate studies in women for determining risk when using this Naphazoline during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Naphazoline. Naphazoline is pregnancy risk category C according to the US Food and Drug Administration (FDA).
FDA pregnancy risk category reference below:
- A=No risk,
- B=No risk in some studies,
- C=There may be some risk,
- D=Positive evidence of risk,
What side effects can occur from Naphazoline?
Stinging, redness, widened pupils, or blurred vision may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if any of these unlikely but serious side effects occur: dizziness, nausea, sweating, drowsiness, weakness, nervousness, worsening redness/itching/swelling in or around the eyes.
Tell your doctor right away if any of these rare but very serious side effects occur: eye pain, other vision problems, headache, decrease in body temperature, irregular heartbeat.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.
What drugs may interact with Naphazoline?
Some products that may interact with this drug include: cyclobenzaprine, guanethidine, MAO inhibitors (linezolid, methylene blue, moclobemide, phenelzine procarbazine, rasagiline, safinamide, selegiline, isocarboxazid, tranylcypromine), maprotiline, tricyclic antidepressants (e.g., amitriptyline).
Naphazoline may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.
Does food or alcohol interact with Naphazoline?
Naphazoline may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.
What health conditions may interact with Naphazoline?
Naphazoline may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.
The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using this Naphazoline.
What is the dose of Naphazoline for an adult?
The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
For ophthalmic solution (eye drop) dosage form:
- For eye redness:
- Adults—Use one drop not more often than every four hours.
What is the dose of Naphazoline for a child?
The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.
How is Naphazoline available?
Naphazoline is available in the following dosage forms and strengths:
- Eye drops
What should I do in case of an emergency or overdose?
In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.
What should I do if I miss a dose?
If you miss a dose of Naphazoline, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.
Hello Health Group does not provide medical advice, diagnosis or treatment.
Naphazoline (Ophthalmic). https://www.drugs.com/cdi/naphazoline-ophthalmic.html. Accessed March 23, 2018.
Naphazoline HCL Drops. https://www.webmd.com/drugs/2/drug-5611/naphazoline-ophthalmic-eye/details. Accessed March 23, 2018.
Review Date: March 30, 2018 | Last Modified: September 12, 2019