By Medically reviewed by hellodoktor

Generic Name: Naclof Brand Name(s): Naclof.


What is Naclof® (diclofenac sodium) used for?

Naclof® is commonly used for:

  • Post-operative inflammation in cataract surgery and other surgical interventions
  • Alleviation of eye pain and photophobia
  • Post-traumatic inflammation in non-invasive injuries
  • Inhibition of miosis during cataract surgery
  • Prevention of cystoid macular edema, arising after extraction of the lens in cataract and implantation of new ocular lens

How should I take Naclof® (diclofenac sodium)?

Before putting in your eye drops, you need to wash your hand and make sure not to let the tip of the dropper touch any surface.

Firstly, tilt your head back, pull down the lower lid of your eye with your index finger to form a pocket. Hold the dropper (tip down) with the other hand, as close to the eye as possible without touching it. While looking up, gently squeeze the dropper so that a single drop falls into the pocket made by the lower eyelid. Remove your index finger from the lower eyelid. Close your eye for 2 to 3 minutes and tip your head down as though looking at the floor. Try not to blink or squeeze your eyelids. Place a finger on the tear duct and apply gentle pressure. Wipe any excess liquid from your face with a tissue.

Dispenser remains sterile until the original closure. Do not touch the end of the applicator to the eye or surrounding structures as this may contaminate the solution.

If necessary, the application of more than one drug in the eye must be ensured 5-minute interval between administration of each drug.

If you wear contact lenses, you need to remove them before instillation of Naclof® and wait 15 minutes after that, before putting them back.

How do I store Naclof® (diclofenac sodium)?

Naclof® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Naclof® in the bathroom or the freezer. There may be different brands of Naclof® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Naclof® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Naclof® (diclofenac sodium)?

Before using Naclof®, tell your doctor if:

  • You have or previously had hypersensitivity to the active substance or to any of the excipients.
  • You have asthma, urticaria or acute rhinitis, your symptoms may be intensified due to inhibition of prostaglandin synthesis.
  • You have or have had hypersensitivity reactions to acetylsalicylic acid, derivatives of phenylacetate and other NSAIDs.

Be especially careful when using Naclof®, because:

  • Anti-inflammatory activity of ophthalmic non-steroidal anti-inflammatory drugs (NSAIDs) may mask the onset and / or progression of ocular infections.
  • If you have an eye infection, your doctor will prescribe you a treatment that can apply simultaneously Naclof®.
  • If you get drugs that prolong bleeding time (anticoagulants) or you have bleeding problems, tell your doctor about it.
  • Eye drops are not for injection. They should never be injected into the eye.
  • If you wear soft contact lenses. The lenses must be removed before dispensing and can be placed again at least 15 minutes afterwards.
  • There is not recommended for use in children 2 years and older.
  • Naclof® can cause blurred vision If you experience these symptoms, you should not drive or operate machinery.

Is it safe during pregnancy or breastfeeding?

There isn’t enough information about the safety of using Naclof® during pregnancy and breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Naclof®.

Side effects

What side effects can occur from Naclof® (diclofenac sodium)?

The most common side effect is transient, mild to moderate burning sensation in the eye. Other less common side effects include itching, redness of the eye, blurred vision immediately after instillation of the eye drops.

Keratitis punctata or corneal epithelial defects are observed, usually after frequent application.

In patients at risk for corneal ulcers and thinning, as seen in the use of corticosteroids or in patients with concomitant diseases (such as infections or rheumatoid arthritis), in rare cases, diclofenac has been associated with corneal ulcer or thinning. Most patients were treated for a prolonged period of time.

In rare cases have been reported dyspnoea and exacerbation of asthma.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with Naclof® (diclofenac sodium)?

Naclof® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Naclof® (diclofenac sodium)?

Naclof® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Naclof® (diclofenac sodium)?

Naclof® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Naclof® (diclofenac sodium).

What is the dose of Naclof® (diclofenac sodium) for an adult?

Ocular surgery and complications:

Preoperatively: The recommended dose is up to 5 times in 1 drop within 3 hours before the operation.

Postoperatively: The recommended dose is 3 times in 1 drop per day of the operation, and subsequently 3-5 times 1 drop a day, as needed.

Alleviation of pain and sensitivity to light (Photophobia):

The recommended dose is one drop of 4-6 hours.

When pain is due to a surgical procedure (e.g., a refractive surgery), 1-2 drops within one hour prior to surgery, 1 to 2 drops within the first 15 min. After the operation, the recommended dose is 1 drop every 4 to 6 hours during the next 3 days .

What is the dose of Naclof® (diclofenac sodium) for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Naclof® (diclofenac sodium) available?

Naclof® is available in the following dosage forms and strengths:

  • Solution; Ophthalmic; Diclofenac Sodium 0.1%
  • 1 ml of drug contains 1 mg of diclofenac of sodium

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Naclof®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.


Review Date: March 25, 2017 | Last Modified: September 13, 2019

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