Generic Name: Morihepamin Brand Name(s): Generics only. No brands available.

Uses

What is Morihepamin (Amino acid preparations) used for?

Morihepamin is commonly used for the supportive treatment for hepatic encephalopathy syndrome in patients with chronic liver disorder.

How should I take Morihepamin (Amino acid preparations)?

Morihepamin should be injected slowly into a vein. If administrated via a central venous line, morihepamin 500 ml should be mixed with a carbohydrate-containing solution and be infused continuously via a central vein for 24 hrs.

Do not use if the solution is absolutely not clear.

How do I store Morihepamin (Amino acid preparations)?

Morihepamin is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store morihepamin in the bathroom or the freezer. There may be different brands of morihepamin that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush morihepamin down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Morihepamin (Amino acid preparations)?

Morihepamin can be injected without using an air vent needle.

Do not open the outer wrap until use, to prevent discoloration of the solution (a deoxidizer is included inside the outer wrap to maintain stability).

Do not use morihepamin if any discoloration or leakage of the solution is noted, or droplets are present inside the outer wrap.

Do not use morihepamin if the seal covering the rubber plug of a plastic bag is peeled off.

A needle should be vertically inserted at the circled (concave) portion of the rubber plug. If the needle is obliquely inserted, the needle may penetrate through the plastic bag, resulting in leakage of the solution.

Caution should be exercised not to damage the outer wrap. If the outer wrap was damaged, the solution may be discolored.

The scale printed on a plastic bag should be used only as a guide.

Morihepamin cannot be infused by the tandem system using a connecting tube (U-shaped tube). If 2 plastic bags are infused at the same time or sequentially, a Y-shaped infusion set must be used.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using morihepamin during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking morihepamin. This medication is pregnancy risk category C, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from Morihepamin (Amino acid preparations)?

Some side effects can occur when using this drug, including:

  • Rash (hypersensitivity)
  • Nausea/queasy (gastrointestinal)
  • Chest discomfort/palpitations (Cardiovascular)
  • Glucose metabolism/ tremor limb (hypoglycemia)
  • Chills
  • Fever
  • Headache
  • Vascular pain
  • Sweaty
  • Urticaria

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Morihepamin (Amino acid preparations)?

Morihepamin may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Morihepamin (Amino acid preparations)?

Morihepamin may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Morihepamin (Amino acid preparations)?

Morihepamin may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Morihepamin (Amino acid preparations).

What is the dose of Morihepamin (Amino acid preparations) for an adult?

Morihepamin is usually IV drip-infused at a single dose of 500 ml in adult patients. The standard infusion rate in adults is ≥180 min per 500 ml.

The dosage may be adjusted according to the patient’s age, symptoms and body weight.

Use in the elderly:

In general, since physiological function is decreased in the elderly, Morihepamin should be carefully administered and be taken with precautionary measures e.g., dose reduction.

What is the dose of Morihepamin (Amino acid preparations) for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Morihepamin (Amino acid preparations) available?

Morihepamin is available in the following dosage forms and strengths:

  • Infusion 200 mL x 30’s.
  • Infusion 500 mL x 20’s.

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

Acetate ion is contained by about 100 mEq/L, therefore in the case of large-dose administration or combined use with electrolyte, due attention should be paid to the electrolyte balance.

What should I do if I miss a dose?

If you miss a dose of Morihepamin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: January 4, 2017 | Last Modified: January 4, 2017

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