What is Methazolamide used for?
Methazolamide is used to treat high pressure inside the eye due to certain types of glaucoma. Lowering high pressure inside the eye helps to prevent blindness, vision loss, and nerve damage. Methazolamide belongs to a class of drugs known as carbonic anhydrase inhibitors. It works by decreasing the production of fluid inside the eye.
How should I take Methazolamide?
Take this medication by mouth as directed by your doctor, usually 2 or 3 times a day. This medication may be taken with food if stomach upset occurs. To reduce your risk of certain side effects (kidney stones), drink plenty of fluids unless otherwise directed by your doctor.
The dosage is based on your medical condition and response to treatment.
Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day. Keep taking this medication even if you feel well. Most people with glaucoma or high pressure in the eye(s) do not feel sick.
How do I store Methazolamide?
Methazolamide is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Methazolamide in the bathroom or the freezer. There may be different brands of Methazolamide that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.
You should not flush Methazolamide down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.
Precautions & warnings
What should I know before using Methazolamide?
Before taking methazolamide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: adrenal gland problems (such as Addison’s disease), liver disease (such as cirrhosis), breathing problems (such as chronic obstructive pulmonary disease-COPD, emphysema, lung infection), diabetes, gout, kidney problems (such as history of kidney stones), untreated mineral imbalance (such as low sodium/potassium, hyperchloremic acidosis), overactive thyroid (hyperthyroidism).
This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.
This medication may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. Tell your doctor right away if you get sunburned or have skin blisters/redness.
Before having surgery, tell your doctor or dentist about all the products you use (such as prescription drugs, nonprescription drugs, and herbal products).
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.
Is it safe during pregnancy or breast-feeding?
There are no adequate studies in women for determining risk when using this Methazolamide during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Methazolamide. Methazolamide is pregnancy risk category C according to the US Food and Drug Administration (FDA).
FDA pregnancy risk category reference below:
- A=No risk,
- B=No risk in some studies,
- C=There may be some risk,
- D=Positive evidence of risk,
What side effects can occur from Methazolamide?
Nausea, loss of appetite, change in taste, vomiting, diarrhea, frequent urination, dizziness, drowsiness, or tiredness may occur as your body adjusts to the medication. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any serious side effects, such as: signs of kidney stones (such as painful urination, fever, chills, pink/bloody urine), signs of infection (such as sore throat that doesn’t go away, fever, chills), easy bleeding/bruising, numbness or tingling of hands/feet, ringing in the ears.
Get medical help right away if you have any very serious side effects, such as: nausea/vomiting that doesn’t stop, loss of appetite, stomach/abdominal pain, yellowing of eyes/skin, dark urine, confusion, fast/pounding heartbeat, seizures.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, such as: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.
What drugs may interact with Methazolamide?
Some products that may interact with this drug are: memantine, methenamine.
Check the labels on all your medicines because they may contain aspirin or aspirin-like drugs (salicylates), which can cause serious side effects if taken in large doses with this medication. However, if your doctor has directed you to take low-dose aspirin for heart attack or stroke prevention (usually at dosages of 81-325 milligrams a day), you should continue taking it unless your doctor instructs you otherwise. Ask your doctor or pharmacist for more details.
This medication may interfere with certain lab tests, possibly causing false test results. Make sure lab personnel and all your doctors know you use this drug.
Methazolamide may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.
Does food or alcohol interact with Methazolamide?
Methazolamide may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.
What health conditions may interact with Methazolamide?
Methazolamide may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.
The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using this Methazolamide.
What is the dose of Methazolamide for an adult?
Usual Adult Dose for Glaucoma
50 to 100 mg orally 2 or 3 times a day
Comments: May be used concomitantly with miotic and osmotic agents.
Use: Treatment of ocular conditions where lowering intraocular pressure is likely to be of therapeutic benefit, such as chronic open-angle glaucoma, secondary glaucoma, and preoperatively in acute angle-closure glaucoma.
Renal Dose Adjustments
Contraindicated in marked renal dysfunction
Liver Dose Adjustments
Contraindicated in marked liver dysfunction
-Monitor for hematologic reactions common to all sulfonamides; perform a CBC and platelet count prior to initiating therapy and regularly thereafter.
-Monitor serum electrolytes periodically.
-Advise patients to seek immediate medical attention if any of the following sulfonamide reactions occur: anaphylaxis, fever, rash (including erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis), crystalluria, renal calculus, bone marrow depression, thrombocytopenic purpura, hemolytic anemia, leukopenia, pancytopenia and agranulocytosis.
-Inform patients of the risk associated with coadministration of this drug and high-dose aspirin (anorexia, tachypnea, lethargy, coma, and death).
What is the dose of Methazolamide for a child?
The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.
How is Methazolamide available?
Methazolamide is available in the following dosage forms and strengths:
- Oral Tablet
What should I do in case of an emergency or overdose?
In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.
What should I do if I miss a dose?
If you miss a dose of Methazolamide, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.
Hello Health Group does not provide medical advice, diagnosis or treatment.
Methazolamide Dosage. https://www.drugs.com/dosage/methazolamide.html. Accessed March 15, 2018.
Methazolamide. https://www.webmd.com/drugs/2/drug-11642/methazolamide-oral/details. Accessed March 15, 2018.
Review Date: March 23, 2018 | Last Modified: September 12, 2019