Metaproterenol Sulfate

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Generic Name: Metaproterenol Sulfate Brand Name(s): Generics only. No brands available. Avability: Rx Pregnancy Category: C

Uses

What is Metaproterenol Sulfate used for?

Metaproterenol Sulfate is used to treat wheezing and shortness of breath from lung problems (e.g., asthma, chronic obstructive pulmonary disease, bronchitis, emphysema). Controlling these symptoms can decrease time lost from work or school. Metaproterenol is a bronchodilator (beta-2 receptor agonist) that works by opening breathing passages to make breathing easier. This drug is also known as orciprenaline in other countries.

How should I take Metaproterenol Sulfate?

Take this medication by mouth with or without food, usually 3-4 times daily or as directed by your doctor. Dosage is based on your medical condition and response to therapy.

If taking the syrup, measure the dose carefully using a medication cup/spoon available from your pharmacist.

Take this medication exactly as prescribed. Do not take more of this medication or take it more often than recommended by your doctor. If you have been directed to use this medication on a daily schedule, use it regularly at the same times each day in order to get the most benefit from it.

If you take other asthma drugs by mouth or inhaling devices, ask your doctor about how to correctly take this medication with your other asthma medicines.

If you notice less effect than usual from this medication, if your symptoms get worse, or if you feel you need to take any of your asthma medications more often than recommended, seek immediate medical attention.

How do I store Metaproterenol Sulfate?

Metaproterenol Sulfate is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Metaproterenol Sulfate in the bathroom or the freezer. There may be different brands of Metaproterenol Sulfate that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Metaproterenol Sulfate down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Metaproterenol Sulfate?

Before taking metaproterenol, tell your doctor or pharmacist if you are allergic to it; or to similar bronchodilators (e.g., albuterol, salmeterol, terbutaline); or to sympathomimetic drugs (e.g., epinephrine, pseudoephedrine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart disease (e.g., other abnormal heartbeat, ischemic heart disease, high blood pressure), seizures, overactive thyroid (hyperthyroidism), diabetes.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

The elderly may be at greater risk for the effects on the heart while using this drug.

This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.

It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.

Is it safe during pregnancy or breast-feeding?

There are no adequate studies in women for determining risk when using this Metaproterenol Sulfate during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Metaproterenol Sulfate. Metaproterenol Sulfate is pregnancy risk category C according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk,
  • B=No risk in some studies,
  • C=There may be some risk,
  • D=Positive evidence of risk,
  • X=Contraindicated,
  • N=Unknown

Side effects

What side effects can occur from Metaproterenol Sulfate?

Shaking, headache, nervousness, tiredness, dizziness, upset stomach, nausea, trouble sleeping or diarrhea may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Tell your doctor right away if any of these unlikely but serious side effects occur: fast/pounding/irregular heartbeat, muscle cramps, weakness.

Seek immediate medical attention if this unlikely but serious side effect occurs: chest pain.

Rarely, this medication has caused severe (rarely fatal), sudden worsening of breathing problems/asthma (paradoxical bronchospasm). If you experience sudden wheezing, seek immediate medical attention.

A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Metaproterenol Sulfate?

Metaproterenol Sulfate may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Metaproterenol Sulfate?

Metaproterenol Sulfate may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

This drug may make you dizzy. Alcohol or marijuana can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana.

What health conditions may interact with Metaproterenol Sulfate?

Metaproterenol Sulfate may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: certain types of heart rhythm problems (cardiac arrhythmias with tachycardia).

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using this Metaproterenol Sulfate.

What is the dose of Metaproterenol Sulfate for an adult?

Usual Adult Dose for Asthma – Acute

Oral: 20 mg 3 to 4 times a day.

Inhalation aerosol: 2 to 3 inhalations every 3 to 4 hours, up to 12 inhalations/day.

Inhalation solution: 10 to 15 mg (0.2 to 0.3 mL of 5% solution) every 4 to 6 hours.

Usual Adult Dose for Asthma – Maintenance

Oral: 20 mg 3 to 4 times a day.

Inhalation aerosol: 2 to 3 inhalations every 3 to 4 hours, up to 12 inhalations/day.

Inhalation solution: 10 to 15 mg (0.2 to 0.3 mL of 5% solution) every 4 to 6 hours.

Usual Adult Dose for Chronic Obstructive Pulmonary Disease – Acute

Oral: 20 mg 3 to 4 times a day.

Inhalation aerosol: 2 to 3 inhalations every 3 to 4 hours, up to 12 inhalations/day.

Inhalation solution: 10 to 15 mg (0.2 to 0.3 mL of 5% solution) every 4 to 6 hours.

Usual Adult Dose for Chronic Obstructive Pulmonary Disease – Maintenance

Oral: 20 mg 3 to 4 times a day.

Inhalation aerosol: 2 to 3 inhalations every 3 to 4 hours, up to 12 inhalations/day.

Inhalation solution: 10 to 15 mg (0.2 to 0.3 mL of 5% solution) every 4 to 6 hours.

What is the dose of Metaproterenol Sulfate for a child?

Usual Pediatric Dose for Asthma – Acute

Infants and children: Nebulizer: 0.5 to 1 mg/kg ( 0.01 to 0.02 mL/kg of 5% solution); minimum dose: 5 mg (0.1 mL); maximum dose: 15 mg (0.3 mL); every 4 to 6 hours.

Children less than 2 years of age: Oral: 0.4 mg/kg/dose in 3 to 4 divided doses a day. In infants, the dose can be given every 8 to 12 hours.

Children 2 to 6 years of age: Oral: 1.3 to 2.6 mg/kg/day divided every 6 to 8 hours.

Children 6 to 9 years of age: Oral: 10 mg 3 to 4 times a day.

Children more than 9 years of age: Oral: 20 mg 3 to 4 times a day.

Children more than 12 years of age: Inhalation aerosol: 2 to 3 inhalations every 3 to 4 hours, up to 12 inhalations in 24 hours.

Usual Pediatric Dose for Asthma – Maintenance

Infants and children: Nebulizer: 0.5 to 1 mg/kg ( 0.01 to 0.02 mL/kg of 5% solution); minimum dose: 5 mg (0.1 mL); maximum dose: 15 mg (0.3 mL); every 4 to 6 hours.

Children less than 2 years of age: Oral: 0.4 mg/kg/dose in 3 to 4 divided doses a day. In infants, the dose can be given every 8 to 12 hours.

Children 2 to 6 years of age: Oral: 1.3 to 2.6 mg/kg/day divided every 6 to 8 hours.

Children 6 to 9 years of age: Oral: 10 mg 3 to 4 times a day.

Children more than 9 years of age: Oral: 20 mg 3 to 4 times a day.

Children more than 12 years of age: Inhalation aerosol: 2 to 3 inhalations every 3 to 4 hours, up to 12 inhalations in 24 hours.

Usual Pediatric Dose for Chronic Obstructive Pulmonary Disease – Acute

Infants and children: Nebulizer: 0.5 to 1 mg/kg ( 0.01 to 0.02 mL/kg of 5% solution); minimum dose: 5 mg (0.1 mL); maximum dose: 15 mg (0.3 mL); every 4 to 6 hours.

Children less than 2 years of age: Oral: 0.4 mg/kg/dose in 3 to 4 divided doses a day. In infants, the dose can be given every 8 to 12 hours.

Children 2 to 6 years of age: Oral: 1.3 to 2.6 mg/kg/day divided every 6 to 8 hours.

Children 6 to 9 years of age: Oral: 10 mg 3 to 4 times a day.

Children more than 9 years of age: Oral: 20 mg 3 to 4 times a day.

Children more than 12 years of age: Inhalation aerosol: 2 to 3 inhalations every 3 to 4 hours, up to 12 inhalations in 24 hours.

Usual Pediatric Dose for Chronic Obstructive Pulmonary Disease – Maintenance

Infants and children: Nebulizer: 0.5 to 1 mg/kg ( 0.01 to 0.02 mL/kg of 5% solution); minimum dose: 5 mg (0.1 mL); maximum dose: 15 mg (0.3 mL); every 4 to 6 hours.

Children less than 2 years of age: Oral: 0.4 mg/kg/dose in 3 to 4 divided doses a day. In infants, the dose can be given every 8 to 12 hours.

Children 2 to 6 years of age: Oral: 1.3 to 2.6 mg/kg/day divided every 6 to 8 hours.

Children 6 to 9 years of age: Oral: 10 mg 3 to 4 times a day.

Children more than 9 years of age: Oral: 20 mg 3 to 4 times a day.

Children more than 12 years of age: Inhalation aerosol: 2 to 3 inhalations every 3 to 4 hours, up to 12 inhalations in 24 hours.

How is Metaproterenol Sulfate available?

Metaproterenol Sulfate is available in the following dosage forms and strengths:

  • Inhalation aerosol with adapter,
  • Inhalation solution,
  • Oral syrup,
  • Oral tablet,
  • Inhalation aerosol,
  • Compounding powder.

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Metaproterenol Sulfate, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: November 16, 2018 | Last Modified: November 16, 2018

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