By Medically reviewed by hellodoktor

Generic Name: Meprobamate Brand Name(s): Meprobamate and Meprobamate.


What is Meprobamate used for?

Meprobamate is used short-term to treat symptoms of anxiety and nervousness. It acts on certain centers of the brain to help calm your nervous system.

How should I take Meprobamate?

Take this medication by mouth with or without food, usually 2 to 4 times daily or as directed by your doctor.

Dosage is based on your age, medical condition, and response to treatment. Adults should not take more than 2400 milligrams in a 24-hour period.

Do not increase your dose or take this medication more often than prescribed. Your condition will not improve any faster, and the risk of serious side effects may be increased.

If this medication has been used regularly for a long time or in high doses, withdrawal symptoms (such as vomiting, shakiness, confusion, and rarely seizures) may occur if you suddenly stop using this medication. To prevent withdrawal reactions, your doctor may reduce your dose gradually. Consult your doctor or pharmacist for more details, and report any withdrawal reactions right away.

When this medication is used for a long time, it may not work as well. Your doctor may need to increase your dose or change your medication. Talk with your doctor if this medication stops working well.

Though it helps many people, this medication may sometimes cause addiction. This risk may be higher if you have a substance use disorder (such as overuse of or addiction to drugs/alcohol). Take this medication exactly as prescribed to lower the risk of addiction. Ask your doctor or pharmacist for more details.

Tell your doctor if your condition persists or worsens.

How do I store Meprobamate?

Meprobamate is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Meprobamate in the bathroom or the freezer. There may be different brands of Meprobamate that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Meprobamate down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Meprobamate?

Before taking meprobamate, tell your doctor or pharmacist if you are allergic to it; or to carisoprodol, mebutamate, tybamate, or carbromal; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: a certain liver/blood disorder (porphyria), kidney disease, liver disease, brain disorders (such as seizures, brain damage), personal or family history of a substance use disorder (such as overuse of or addiction to drugs/alcohol).

This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.

Older adults may be more sensitive to the side effects of this drug, especially drowsiness and addiction. Drowsiness can increase the risk of falling.

This medication is not recommended for use during the first 3 months of pregnancy due to the potential for harm to an unborn baby. During the last 6 months of pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

This medication passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.

Is it safe during pregnancy or breast-feeding?

There are no adequate studies in women for determining risk when using this Meprobamate during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Meprobamate. Meprobamate is pregnancy risk category N according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk,
  • B=No risk in some studies,
  • C=There may be some risk,
  • D=Positive evidence of risk,
  • X=Contraindicated,
  • N=Unknown

Side effects

What side effects can occur from Meprobamate?

Drowsiness, dizziness, headache, excitement, nausea, vomiting, and diarrhea may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if any of these unlikely but serious side effects occur: numbness/tingling/swelling of arms/legs.

Tell your doctor right away if any of these rare but very serious side effects occur: fast/irregular heartbeat, fainting, signs of infection (such as fever, persistent sore throat), easy bruising/bleeding, signs of kidney problems (such as change in the amount of urine), unusual tiredness.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with Meprobamate?

Tell your doctor or pharmacist if you are taking other products that cause drowsiness, including alcohol, marijuana, antihistamines (such as cetirizine, diphenhydramine), drugs for sleep or anxiety (such as alprazolam, diazepam, zolpidem), muscle relaxants (such as carisoprodol), and narcotic pain relievers (such as codeine).

Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.

Meprobamate may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Meprobamate?

Meprobamate may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Meprobamate?

Meprobamate may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using this Meprobamate.

What is the dose of Meprobamate for an adult?

Usual Adult Dose for Anxiety

1200 to 1600 mg orally divided in 3 or 4 doses

Maximum dose: 2400 mg per day


-The lowest effective dose should be used in order to limit oversedation.

-The effectiveness beyond 4 months has not been assessed.

Uses: Management of anxiety disorders or for the short-term relief of anxiety symptoms.

Renal Dose Adjustments

Use with caution

Liver Dose Adjustments

Use with caution

Dose Adjustments

Elderly: Use with cation; dose selection should be cautious starting at the low end of the dosing range.

Abrupt discontinuation should be avoided; reduce dose gradually over a period of 1 to 2 weeks; alternatively, a long-acting barbiturate may be substituted, then gradually withdrawn.

Other Comments

Administration advice:

-Take orally 3 to 4 times a day


-Careful supervision of dose and amounts prescribed is necessary since this drug is known to produce physical and psychological dependence.

-Abrupt discontinuation, especially after prolonged use, should be avoided; onset of withdrawal symptoms is usually within 12 to 48 hours and symptoms usually cease within the next 12 to 48 hours.

-Continued need should be regularly reassessed.


-Monitor for over sedation

-Monitor for abuse

Patient advice:

-Patients should be advised that this drug may impair their ability to perform hazardous tasks including driving.

-Patients should be aware that this drug has been known to be abused producing physical and psychological dependence when used at higher than recommended doses; withdrawal reactions are possible and patients should discuss discontinuation with their healthcare provider.

-Patients should be informed that their tolerance for alcohol and other CNS depressants will be diminished; concurrent use is generally not recommended, but should be discussed with their healthcare provider.

What is the dose of Meprobamate for a child?

Usual Pediatric Dose for Anxiety

Age: 6 to 12 years:

200 to 600 mg orally divided in 2 or 3 doses

Age: 13 years or older:

1200 to 1600 mg orally divided in 3 or 4 doses

Maximum dose: 2400 mg per day


-The lowest effective dose should be used in order to limit oversedation.

-The effectiveness beyond 4 months has not been assessed.

Uses: Management of anxiety disorders or for the short-term relief of anxiety symptoms


Safety and efficacy have not been established in patients younger than 6 years.

How is Meprobamate available?

Meprobamate is available in the following dosage forms and strengths:

  • Oral Tablet

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Meprobamate, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Review Date: March 23, 2018 | Last Modified: September 12, 2019

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