Generic Name: Meprasac Brand Name(s): Generics only. No brands available.

Uses

What is Meprasac® (omeprazole) used for?

Meprasac® is commonly used to treat gastric and duodenal ulcers, erosive esophagitis, gastroesophageal reflux disease (GERD), and Zollinger-Ellison syndrome. It is also used to treat dyspepsia, a condition that causes sour stomach, belching, heartburn, or indigestion.

In addition, Meprasac® is used to prevent upper gastrointestinal tract bleeding in seriously ill patients.

Sometimes, Meprasac® is used in combination with antibiotics (e.g., amoxicillin, clarithromycin) to treat ulcers associated with infection caused by the H. pylori bacteria (germ).

How should I take Meprasac® (omeprazole)?

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

Swallow it whole. Do not chew or crush. Drink it with a full glass of water.

How do I store Meprasac® (omeprazole)?

Meprasac® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Meprasac® in the bathroom or the freezer. There may be different brands of Meprasac® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Meprasac® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Meprasac® (omeprazole)?

Before using this drug, tell your doctor if:

  • You are allergic to any ingredient in Meprasac® or to any benzimidazole medicine such as albendazole or mebendazole.
  • You are pregnant, planning to become pregnant, or are breastfeeding.
  • You are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement.
  • You have allergies to medicines, foods, or other substances.

Is it safe during pregnancy or breastfeeding?

There isn’t enough information about the safety of using Meprasac® during pregnancy and breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Meprasac®.

Side effects

What side effects can occur from Meprasac® (omeprazole)?

When using this drug, some side effects may occur. Consult your doctor immediately if:

  • Back, leg, or stomach pain
  • Bleeding or crusting sores on the lips
  • Blisters
  • Bloody or cloudy urine
  • Chills
  • Continuing ulcers or sores in the mouth
  • Difficult, burning, or painful urination
  • Fever
  • Frequent urge to urinate
  • General feeling of discomfort or illness
  • Joint pain
  • Loss of appetite
  • Muscle aches or cramps
  • Pain
  • Red or irritated eyes
  • Redness, tenderness, itching, burning, or peeling of the skin
  • Skin rash or itching
  • Sore throat
  • Sores, ulcers, or white spots on the lips, in the mouth, or on the genitals
  • Unusual bleeding or bruising
  • Unusual tiredness or weakness

Some common side effects may include:

  • Lightheadedness
  • Taste disturbance
  • Taste perversion
  • Headache
  • Drowsiness
  • Somnolence
  • Dizziness
  • Diarrhea
  • Abdominal pain
  • Constipation
  • Flatulence
  • Nausea/vomiting
  • Acid regurgitation
  • Tongue discoloration
  • Upper respiratory infection
  • Cough
  • Rhinitis
  • Pharyngitis/pharyngeal pain
  • Bronchospasm
  • Otitis media
  • Fever
  • Asthenia
  • Flu-syndrome
  • Malaise
  • Rash
  • Dermatitis
  • Alopecia
  • Skin eruptions
  • Erythema multiforme
  • Urticaria and/or pruritus
  • Insomnia
  • Agitation
  • Confusion/reversible mental confusion
  • Depression
  • Aggression
  • Hallucinations
  • Back pain
  • Peripheral edema

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Meprasac® (omeprazole)?

Meprasac® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products may interact with your drug, such as:

  • Antiretroviral Therapy
  • Saquinavir
  • Clopidogrel
  • Tacrolimus
  • Clarithromycin
  • Methotrexate

Does food or alcohol interact with Meprasac® (omeprazole)?

Meprasac® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Meprasac® (omeprazole)?

Meprasac® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Especially if you have:

  • Liver disease
  • Low levels of magnesium in your blood
  • Osteoporosis or low bone mineral density (osteopenia)

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Meprasac® (omeprazole).

What is the dose of Meprasac® (omeprazole) for an adult?

Duodenal Ulcer

The recommended dose is 20 mg orally once a day.

Duration of therapy is 4 weeks.

Helicobacter pylori Infection

Dual therapy:

The recommended dose is 40 mg orally once a day, taken concomitantly with clarithromycin.
Duration of therapy is 14 days.

Triple therapy:

The recommended dose is 20 mg orally 2 times a day, taken concomitantly with amoxicillin and clarithromycin.

Duration of therapy is 10 days.

Gastric Ulcer

The recommended dose is 40 mg orally once a day.

Duration of therapy is 4 to 8 weeks.

Erosive Esophagitis

Treatment:
The recommended dose is 20 mg orally once a day.

Duration of therapy is 4 to 8 weeks.

Maintenance:
The recommended dose is 20 mg orally once a day.

Multiple Endocrine Adenomas

The initial dose is 60 mg orally once a day.

The maximum dose is 360 mg/day (as 120 mg orally 3 times a day).

Systemic Mastocytosis

The initial dose is 60 mg orally once a day.

The maximum dose is 360 mg/day (as 120 mg orally 3 times a day).

Zollinger-Ellison Syndrome

The initial dose is 60 mg orally once a day.

The maximum dose is 360 mg/day (as 120 mg orally 3 times a day).

Hypersecretory Conditions

The initial dose is 60 mg orally once a day.

The maximum dose is 360 mg/day (as 120 mg orally 3 times a day).

Gastroesophageal Reflux Disease

The recommended dose is 20 mg orally once a day.

Duration of therapy is up to 4 weeks.

Dyspepsia

The recommended dose is 20 mg orally once a day in the morning.

Duration of therapy is 14 days.

What is the dose of Meprasac® (omeprazole) for a child?

Gastroesophageal Reflux Disease

1 to 16 years:

  • 5 to less than 10 kg: The recommended dose is 5 mg orally once a day.
  • 10 to less than 20 kg: The recommended dose is 10 mg orally once a day.
  • 20 kg and greater: The recommended dose is 20 mg orally once a day.
  • Duration of therapy is up to 4 weeks.

16 to 18 years:

  • The recommended dose is 20 mg orally once a day.
  • Duration of therapy is up to 4 weeks.

Erosive Esophagitis

Treatment

1 month to less than 1 year:

  • 3 to less than 5 kg: The recommended dose is 2.5 mg orally once a day.
  • 5 to less than 10 kg: The recommended dose is 5 mg orally once a day.
  • 10 kg and greater: The recommended dose is 10 mg orally once a day.

1 to 16 years:

  • 5 to less than 10 kg: The recommended dose is 5 mg orally once a day.
  • 10 to less than 20 kg: The recommended dose is 10 mg orally once a day.
  • 20 kg and greater: The recommended dose is 20 mg orally once a day.

16 to 18 years:

  • The recommended dose is 20 mg orally once a day.
  • Duration of therapy is 4 to 8 weeks.

Maintenance

1 to 16 years:

  • 5 to less than 10 kg: The recommended dose is 5 mg orally once a day.
  • 10 to less than 20 kg: The recommended dose is 10 mg orally once a day.
  • 20 kg and greater: The recommended dose is 20 mg orally once a day.

16 to 18 years:

  • The recommended dose is 20 mg orally once a day.

Liver Dose Adjustments

Combination therapy with clarithromycin: Avoid use.

Maintenance of healing of erosive esophagitis: The recommended dose is 10 mg orally once a day.

Dose Adjustments

Maintenance of healing of erosive esophagitis in Asian patients:

The recommended dose is 10 mg orally once a day.

How is Meprasac® (omeprazole) available?

Meprasac® is available in the following dosage forms and strengths:

  • Tablet 20mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

Symptoms of overdose are:

  • Blurred vision
  • Confusion
  • Dryness of the mouth
  • Flushing
  • Headache
  • Increased sweating

What should I do if I miss a dose?

If you miss a dose of Meprasac®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

 

Sources

Review Date: April 10, 2017 | Last Modified: April 10, 2017

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