Mebendazole

By Medically reviewed by hellodoktor

Generic Name: Mebendazole Brand Name(s): Generics only. No brands available.

Uses

What is Mebendazole used for?

Mebendazole is used to treat intestinal worm infections such as pinworm, roundworm, and hookworm.

How should I take Mebendazole?

This medication is taken by mouth and can be taken with or without food. It may be chewed, swallowed whole, or crushed and mixed with food.

Dosage is based on your medical condition and response to therapy.

For treatment of pinworm infections, the medication is usually given as a single dose. If necessary, a second treatment may be given in a few weeks. For other types of common worm infections (e.g., roundworm, hookworm), take mebendazole by mouth for 3 days, usually twice a day in the morning and in the evening, or as directed by your doctor. If necessary, a second treatment may be given in a few weeks. For other types of infections, follow your doctor’s directions. Your doctor may order you to take this medication more often than twice a day and for longer than 3 days.

It is very important to continue taking this medication exactly as prescribed by your doctor. Do not skip any doses. Continue to take this medication until the full prescribed amount is finished, even if symptoms disappear. Stopping the medication too early may result in a return of the infection.

Inform your doctor if your condition persists or worsens.

How do I store Mebendazole?

Mebendazole is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Mebendazole in the bathroom or the freezer. There may be different brands of Mebendazole that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Mebendazole down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Mebendazole?

Tell your doctor your medical history, especially of: low blood count (anemia), liver disease, intestinal problems (e.g., Crohn’s disease, ulcerative colitis).

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

This drug passes into breast milk. Consult your doctor before breast-feeding.

Is it safe during pregnancy or breast-feeding?

There are no adequate studies in women for determining risk when using this Mebendazole during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Mebendazole. Mebendazole is pregnancy risk category C according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk,
  • B=No risk in some studies,
  • C=There may be some risk,
  • D=Positive evidence of risk,
  • X=Contraindicated,
  • N=Unknown

Side effects

What side effects can occur from Mebendazole?

Stomach/abdominal pain, vomiting, diarrhea, headache, dizziness, or drowsiness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if any of these rare but very serious side effects occur: severe abdominal pain, easy bleeding/bruising, signs of serious infection (e.g., fever, persistent sore throat), unusual/extreme tiredness, seizures, weakness, dark or pinkish urine, yellowing eyes/skin.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Mebendazole?

A product that may interact with this drug is: metronidazole.

Mebendazole may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Mebendazole?

Mebendazole may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Mebendazole?

Mebendazole may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using this Mebendazole.

What is the dose of Mebendazole for an adult?

Usual Adult Dose for Angiostrongylosis

100 mg orally twice a day for 5 days.

Usual Adult Dose for Ascariasis

100 mg orally twice a day for 3 days. If biliary obstruction is also present, piperazine citrate 150 mg/kg initially, followed by 65 mg/kg every 12 hours for 6 doses by nasogastric tube is also recommended.

Usual Adult Dose for Capillariasis

200 mg orally twice a day for 20 days. Relapses may be treated with prolonged courses of therapy.

Usual Adult Dose for Trichostrongylosis

100 mg orally twice a day for 3 days.

Usual Adult Dose for Filariasis

100 mg orally one time. This dose should be repeated in 2 weeks. All family members and close contacts should also be examined.

Mansonella perstans infection – 100 mg twice daily for 30 days.

Usual Adult Dose for Hookworm Infection (Necator or Ancylostoma)

100 mg orally twice a day for 3 days.

Usual Adult Dose for Whipworm Infection (Trichuris trichiura)

100 mg orally twice a day for 3 days.

Usual Adult Dose for Pinworm Infection (Enterobius vermicularis)

100 mg orally one time. This dose should be repeated in 2 weeks. All family members and close contacts should also be examined.

Usual Adult Dose for Trichinosis

200 to 400 mg orally three times a day for 3 days, then 400 to 500 mg three times a day for 10 days. Concomitant steroid therapy may be administered if patient is symptomatic.

Usual Adult Dose for Visceral Larva Migrans (Toxicariasis)

100 to 200 mg orally twice daily for 5 days. Coadministration of anti-inflammatory agents might be considered.

Usual Adult Dose for Echinococcus Infection

Case Series (n=769)

Hepatic Cystic infection – Larval (tissue stage): 40 to 50 mg/kg per day, administered in three divided doses, in conjunction with percutaneous aspiration-injection-reaspiration (PAIR) drainage, 1 week before and 4 weeks after PAIR drainage.

Usual Adult Dose for Hydatid Disease

Case Series (n=769)

Hepatic Cystic infection – Larval (tissue stage): 40 to 50 mg/kg per day, administered in three divided doses, in conjunction with percutaneous aspiration-injection-reaspiration (PAIR) drainage, 1 week before and 4 weeks after PAIR drainage.

Usual Adult Dose for Dracunculiasis

400 to 800 mg per day for 6 days.

What is the dose of Mebendazole for a child?

Usual Pediatric Dose for Angiostrongylosis

Greater than or equal to 2 years: 100 mg orally twice a day for 5 days.

Usual Pediatric Dose for Ascariasis

Greater than or equal to 2 years: 100 mg orally twice a day for 3 days. If biliary obstruction is also present, piperazine citrate 150 mg/kg initially, followed by 65 mg/kg every 12 hours for 6 doses by nasogastric tube is also recommended.

Usual Pediatric Dose for Capillariasis

Greater than or equal to 2 years: 200 mg orally twice a day for 20 days. Relapses may be treated with prolonged courses of therapy.

Usual Pediatric Dose for Filariasis

Greater than or equal to 2 years: 100 mg orally one time. This dose should be repeated in 2 weeks. All family members and close contacts should also be examined.

Mansonella perstans infection – 100 mg twice daily for 30 days.

Usual Pediatric Dose for Hookworm Infection (Necator or Ancylostoma)

Greater than or equal to 2 years: 100 mg orally twice a day for 3 days.

Usual Pediatric Dose for Whipworm Infection (Trichuris trichiura)

Greater than or equal to 2 years: 100 mg orally twice a day for 3 days.

Usual Pediatric Dose for Pinworm Infection (Enterobius vermicularis)

Greater than or equal to 2 years: 100 mg orally one time. This dose should be repeated in 2 weeks. All family members and close contacts should also be examined.

Usual Pediatric Dose for Trichinosis

Greater than or equal to 2 years: 200 to 400 mg orally three times daily for 3 days, then 400 to 500 mg three times daily for 10 days. Steroids may be administered if patient is symptomatic.

Cases (n=23) – Trichinella nativa infection:

1 to 14 years: 200 mg orally three times daily for the first 3 days, then 400 mg orally three times daily for another 11 days. Concomitant steroid therapy may be administered if patient is symptomatic.

Usual Pediatric Dose for Visceral Larva Migrans (Toxicariasis)

Greater than or equal to 2 years: 100 to 200 mg orally twice daily for 5 days. Coadministration of anti-inflammatory agents might be considered.

Precautions

The safety of mebendazole in children younger than 2 years has not been established.

How is Mebendazole available?

Mebendazole is available in the following dosage forms and strengths:

  • Oral tablet, chewable
  • Compounding powder

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Mebendazole, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Review Date: March 23, 2018 | Last Modified: September 12, 2019

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