Generic Name: Magnesium Oxide Brand Name(s): Generics only. No brands available.

Know the basics

What is magnesium oxide used for?

Magnesium oxide  is a mineral supplement used to prevent and treat low amounts of magnesium in the blood. Magnesium is very important for the normal functioning of cells, nerves, muscles, bones, and the heart. Usually, a well-balanced diet provides normal blood levels of magnesium. However, certain situations cause your body to lose magnesium faster than you can replace it from your diet. These situations include treatment with “water pills” (diuretics such as furosemide,hydrochlorothiazide), a poor diet, alcoholism, or other medical conditions (for example., severe diarrhea/vomiting, stomach/intestinal absorption problems, poorly controlled diabetes).

How should I take magnesium oxide?

Take magnesium oxide by mouth as directed. Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor or pharmacist.

It is best to take magnesium supplements with a meal to reduce stomach upset anddiarrhea unless otherwise directed by the product instructions or your doctor.

Take each dose with a full glass (8 ounces or 240 milliliters) of water unless your doctor directs you otherwise. Swallow extended-release capsules whole. Do not crush or chew extended-release capsules or tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split extended-release tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.

If you are using a liquid product, use a magnesium oxide measuring device to carefully measure the dose. Do not use a household spoon because you may not get the correct dose. If you are using a suspension, shake the bottle well before each dose.

Take magnesium oxide regularly in order to get the most benefit from it. Remember to take it at the same time(s) each day. Dosage is based on your medical condition and response to treatment. Do not increase your dose or take it more often than directed on the product package or by your doctor. Too much magnesium in the blood can cause serious side effects.

Tell your doctor if symptoms of low magnesium blood levels (e.g., muscle cramps, tiredness, irritability, depression) persist or worsen. If you think you may have a serious medical problem, seek immediate medical attention.

How do I store magnesium oxide?

Magnesium oxide is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store magnesium oxide in the bathroom or the freezer. There may be different brands of magnesium oxide that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush magnesium oxide down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard magnesium oxide when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Know the precautions & warnings

What should I know before using magnesium oxide?

Before taking magnesium oxide,

  • Tell your doctor and pharmacist if you are allergic to magnesium oxide, other antacids or laxatives, or any other drugs.
  • Tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially other antacids or laxatives, anticoagulants (‘blood thinners’) such as warfarin (coumadin), aspirin, diuretics (‘water pills’), medicine for ulcers (cimetidine [tagamet], ranitidine [zantac]), and vitamins.
  • Tell your doctor if you have or have ever had heart, kidney, liver, or intestinal disease or high blood pressure.
  • Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking magnesium oxide, call your doctor immediately.
  • Tell your doctor if you are on a low-salt, low-sugar, or other special diet.

Is it safe to take magnesium oxide during pregnancy or breast-feeding?

There are no adequate studies in women for determining risk when using magnesium oxide during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking magnesium oxide. Magnesium oxide is pregnancy risk category  B according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk,
  • B=No risk in some studies,
  • C=There may be some risk,
  • D=Positive evidence of risk,
  • X=Contraindicated,
  • N=Unknown

Know the side effects

What are the side effects of magnesium oxide?

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Seek medical attention right away if any of these SEVERE side effects occur:

  • Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; nausea; slow reflexes; vomit that looks like coffee grounds.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Know the interactions

What drugs may interact with magnesium oxide?

Magnesium oxide may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

  • Anticoagulants (eg, warfarin) because the risk of their side effects may be increased by magnesium oxide.
  • Penicillamine because its effectiveness may be decreased by magnesium oxide.

Does food or alcohol interact with magnesium oxide?

Magnesium oxide may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with magnesium oxide?

Magnesium oxide may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Appendicitis;
  • Diarrhea;
  • A blockage of your intestines;
  • Heart problems;
  • Kidney problems;

Understand the dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using magnesium oxide.

What is the dose of magnesium oxide for an adult?

Usual Adult Dose for Duodenal Ulcer

  • Tablets: 400 to 800 mg (241 to 482 mg elemental magnesium) orally once a day.
  • Capsules: 140 mg (84 mg elemental magnesium) orally 3 to 4 times a day.

Usual Adult Dose for Dyspepsia

  • Tablets: 400 to 800 mg (241 to 482 mg elemental magnesium) orally once a day.
  • Capsules: 140 mg (84 mg elemental magnesium) orally 3 to 4 times a day.

Usual Adult Dose for Gastric Ulcer

  • Tablets: 400 to 800 mg (241 to 482 mg elemental magnesium) orally once a day.
  • Capsules: 140 mg (84 mg elemental magnesium) orally 3 to 4 times a day.

Usual Adult Dose for Gastroesophageal Reflux Disease

  • Tablets: 400 to 800 mg (241 to 482 mg elemental magnesium) orally once a day.
  • Capsules: 140 mg (84 mg elemental magnesium) orally 3 to 4 times a day.

Usual Adult Dose for Hypomagnesemia

  • Tablets: 400 to 800 mg (241 to 482 mg elemental magnesium) orally once a day.
  • Capsules: 140 mg (84 mg elemental magnesium) orally 3 to 4 times a day.

Usual Adult Dose for Pathological Hypersecretory Disorder

  • Tablets: 400 to 800 mg (241 to 482 mg elemental magnesium) orally once a day.
  • Capsules: 140 mg (84 mg elemental magnesium) orally 3 to 4 times a day.

Usual Adult Dose for Renal Stones

  • 140 to 420 mg (84 to 252 mg elemental magnesium) orally once a day. Magnesium oxide has also been used in combination with pyridoxine to prevent recurrence of calcium oxalate renal calculi.

Usual Adult Dose for Constipation

  • Caplets (500 mg): 2 to 4 caplets orally daily with a full 8 ounce glass of liquid.
  • Caplets may be taken all at bedtime or separately throughout the day.

What is the dose of magnesium oxide for a child?

Usual Pediatric Dose for Constipation

  • 12 years or older:
  • caplets (500 mg): 2 to 4 caplets orally daily with a full 8 ounce glass of liquid.
  • caplets may be taken all at bedtime or separately throughout the day.

How is magnesium oxide available?

Magnesium oxide is available in the following dosage forms and strengths:

  • Tablet, Oral: 400 mg, 420 mg
  • Capsule, Oral: 140 mg.

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of magnesium oxide, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: January 4, 2017 | Last Modified: January 4, 2017

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