Lisinopril

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Generic Name: Lisinopril Brand Name(s): Generics only. No brands available.

Uses

What is lisinopril used for?

Lisinopril is an ACE inhibitor. ACE stands for angiotensin converting enzyme.

Lisinopril is used to treat high blood pressure (hypertension) in adults and children who are at least 6 years old.

Lisinopril is also used to treat congestive heart failure in adults, or to improve survival after a heart attack.

How should I take lisinopril?

Take lisinopril exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Drink plenty of water each day while you are taking this medicine.

Lisinopril can be taken with or without food.

Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

How do I store lisinopril?

Lisinopril is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store lisinopril in the bathroom or the freezer. There may be different brands of lisinopril that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush lisinopril down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using lisinopril?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of lisinopril or other medications.
  • You have any other illnesses, disorders, or medical conditions.

Your blood pressure will need to be checked often, and you may need frequent blood tests.

Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking this medicine. This can lead to very low blood pressure, electrolyte disorders, or kidney failure while you are taking lisinopril.

If you need surgery, tell the surgeon ahead of time that you are using lisinopril. You may need to stop using the medicine for a short time.

If you are being treated for high blood pressure, keep using this medication even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.

You should not use this medicine if you have hereditary angioedema.

If you have diabetes, do not use lisinopril together with any medication that contains aliskiren (such as Amturnide, Tekturna, Tekamlo).

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when usin lisinopril during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking lisinopril. Lisinopril is pregnancy risk category D, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from lisinopril?

Common side effects may include:

  • Headache
  • Dizziness
  • Cough
  • Chest pain

Call your doctor at once if you have:

  • A light-headed feeling, like you might pass out
  • Little or no urinating
  • Fever
  • Sore throat
  • High potassium – nausea, slow or unusual heart rate, weakness, loss of movement
  • Kidney problems – little or no urinating, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath
  • Liver problems – nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes)

Get emergency medical help if you have signs of an allergic reaction such as hives; severe stomach pain, difficult breathing; swelling of your face, lips, tongue, or throat.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with lisinopril?

Lisinopril may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products that may interact with this drug are:

  • Lithium
  • A diuretic or “water pill”
  • Gold injections to treat arthritis
  • Insulin or oral diabetes medicine
  • A potassium supplement
  • Medicine to prevent organ transplant rejection – everolimus, sirolimus, tacrolimus, temsirolimus
  • NSAIDs (nonsteroidal anti-inflammatory drugs) – aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.

Does food or alcohol interact with lisinopril?

Lisinopril may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with lisinopril?

Lisinopril may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Health conditions that may interact with this drug are:

  • Kidney disease (or if you are on dialysis)
  • Liver disease
  • Diabetes
  • High levels of potassium in your blood

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using lisinopril.

What is the dose of lisinopril for an adult?

Usual Adult Dose for Hypertension:

Initial dose: 10 mg orally once a day; 5 mg orally once a day.

Maintenance dose: 20 to 40 mg orally once a day.

Maximum dose: 80 mg orally once a day.

Usual Adult Dose for Congestive Heart Failure:

Initial dose: 2.5 to 5 mg orally once a day.

Maintenance dose: Dosage should be increased as tolerated.

Maximum dose: 40 mg orally once a day.

Usual Adult Dose for Myocardial Infarction:

Initial dose: 5 mg orally (within 24 hours of the onset of acute myocardial infarction).

Subsequent doses: 5 mg orally after 24 hours, then 10 mg orally after 48 hours.

Maintenance dose: 10 mg orally once a day. Dosing should continue for at least 6 weeks.

Usual Adult Dose for Diabetic Nephropathy:

Initial dose: 10 to 20 mg orally once a day.

Maintenance dose: 20 to 40 mg orally once a day.

Dosage may be titrated upward every 3 days.

Usual Geriatric Dose for Hypertension:

Initial dose: 2.5 to 5 mg orally once a day.

Maintenance dose: Dosages should be increased at 2.5 mg to 5 mg per day at 1 to 2 week intervals.

Maximum dose: 40 mg orally once a day.

What is the dose of lisinopril for a child?

Usual Pediatric Dose for Hypertension:

Pediatric patients greater than or equal to 6 years of age:

Initial dose: 0.07 mg/kg orally once a day (Maximum initial dose is 5 mg once a day).

Maintenance dose: Dosage should be adjusted according to blood pressure response at 1 to 2 week intervals.

Maximum dose: Doses above 0.61 mg/kg or greater than 40 mg have not been studied in pediatric patients.

How is lisinopril available?

Lisinopril is available in the following dosage forms and strengths:

  • Tablet 2,5mg; 5mg; 10mg; 20mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of lisinopril, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: July 6, 2017 | Last Modified: July 6, 2017

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