Lipofundin

By Medically reviewed by hellodoktor

Generic Name: Lipofundin Brand Name(s): Lipofundin and Lipofundin.

Uses

What is Lipofundin® used for?

Lipofundin® is commonly used for providing fat, including essential fatty acids to patients needing to be fed intravenously (through a small tube placed into a vein) because they are unable to eat food normally or the normal intake is not enough. The oils contained in Lipofundin® are foodstuffs and they act as sources of energy and provide an essential nutrient, the essential fatty acids.

How should I take Lipofundin®?

This medicine will be administered to you by a doctor or healthcare professional. Lipofundin® infusions will not be given alone but always together with sufficient amounts of amino acids and carbohydrate (normally glucose) infusions.

How do I store Lipofundin®?

Lipofundin® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Lipofundin® in the bathroom or the freezer. There may be different brands of Lipofundin® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Lipofundin® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Lipofundin®?

Do not use Lipofundin® if you have:

  • An allergy (hypersensitivity) to eggs or soya-bean protein or to any of the ingredients of the emulsion
  • Severe hyperlipidemia (high levels of fat substances in the blood)
  • Severe blood coagulation disorders (conditions where the blood does not clot properly)
  • Intrahepatic cholestasis (a condition where the flow of bile is impaired)
  • Severe liver failure
  • Severe kidney failure and are not receiving dialysis treatment.
  • Acute heart infarction (heart attack) or stroke
  • Acute blockage of blood vessels by blood clots or fat drops (acute thrombo-embolism, fat embolism)
  • Severely impaired blood circulation, accompanied by massive impairment of heart function, breathing, kidney and liver function, etc.
  • States of collapse or shock
  • Unstable metabolism because of severe injury, diabetes mellitus, severe sepsis (infection involving the whole body) and acidosis (where the blood is too acidic)
  • Unconsciousness (coma) caused by a special metabolic abnormality called keto-acidosis
  • Coma of unknown origin
  • Hypotonic dehydration (too little water and too little salt in the body)
  • Hypokalaemia (abnormally low potassium levels in the blood)

Patients must not receive infusion therapy if one or more of the following conditions are present:

  • Acute pulmonary edema (accumulation of fluid in the lungs)
  • Hyperhydration (too much water in the body)
  • Decompensated cardiac insufficiency (heart failure)

Is it safe during pregnancy or breastfeeding?

Ask your doctor or pharmacist for advice before taking any medicine.

The safety of use of Lipofundin® during pregnancy and lactation has not definitely been established. You will receive this medicine only if the doctor considers it absolutely necessary to save your life or to prevent any serious injury from occurring.

Consideration should be given to stopping breastfeeding temporarily while under treatment with Lipofundin®.

Side effects

What side effects can occur from Lipofundin®?

Undesirable effects occur only very rarely, provided that the instructions for using this product are followed correctly. The following undesirable effects may occur during or after the administration of fat emulsions (side effects are listed according to affected organs or organ systems).

  • Blood, lymphatic system increase tendency of the blood to clot.
  • Immune system may include fever, shivering, rash or dyspnoea (shortness of breath).
  • Metabolism includes high blood fat and blood sugar levels, acidosis.
  • Nervous system includes drowsiness.
  • Circulation likes drop or raise of blood pressure.
  • Lungs, airways include breathing problems, cyanosis (bluish discoloration of the skin).
  • Stomach, gut include feeling sick, vomiting.
  • General disorders include headache, flushing, fever, sweating, chills, chest and back pain.

If any of the side effects gets serious, or if you notice any side effect not listed in this leaflet, please tell your doctor or pharmacist.

Interactions

What drugs may interact with Lipofundin®?

Lipofundin® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Lipofundin®?

Lipofundin® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Lipofundin®?

Before this product is given to you, your doctor will check whether or not you have one or more of the following conditions, in which the body may not be able to use fat correctly:

  • Diabetes mellitus
  • Inflammation of the pancreas (pancreatitis)
  • Impaired liver or kidney function
  • Lung disease
  • Sepsis (infection involving the whole body)
  • Underactive thyroid gland (hypothyroidism)

If you have any of these conditions, Lipofundin® will only be administered if clearly needed and special care will be taken to make sure this product will not be harmful to you.

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Lipofundin®.

What is the dose of Lipofundin® for an adult?

It will be given by an intravenous drip as part of a feeding program. The amount (dose) and the drop (or infusion) rate of the fat emulsion will be decided by your doctor. The daily doses will be adjusted to your needs and body weight.

Lipofundin® will normally be given over a period of 1 week.

Lipofundin® may be given for a longer period time if thought necessary by your doctor. Under these circumstances, you will be carefully monitored.

What is the dose of Lipofundin® for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Lipofundin® available?

Lipofundin® is available in the following dosage forms and strengths:

  • Lipofundin®, glass bottles of 100 ml, 250 ml or 500 ml size

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Lipofundin®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

 

Sources

Review Date: December 25, 2016 | Last Modified: September 12, 2019

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