Lenitral (injection)

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Generic Name: Lenitral (injection) Brand Name(s): Generics only. No brands available.

Uses

What is lenitral (injection) used for?

Lenitral is a nitrate. It works by relaxing (widening) blood vessels. Chest pain occurs when the heart needs more oxygen than it can get. Relaxing blood vessels allows blood to flow more easily. This reduces the heart’s workload and the amount of oxygen needed by the heart.

This drug is commonly used for treating high blood pressure during surgery, controlling congestive heart failure associated with heart attack, treating chest pain in certain patients, and lowering blood pressure during surgery.

How should I take lenitral (injection)?

Lenitral is given as an injection at your doctor’s office, hospital, or clinic. Contact your health care provider if you have any questions.

How do I store lenitral (injection)?

Lenitral is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store lenitral in the bathroom or the freezer. There may be different brands of lenitral that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush lenitral down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using lenitral (injection)?

Before using this drug, tell your doctor if you are allergic to any ingredients of lenitral.

It is very important that your doctor check your progress closely while you are receiving this medicine to make sure it is working properly.

Dizziness, lightheadedness, or faintness may occur, especially when you get up quickly from a lying or sitting position. Getting up slowly may help.

This medicine may cause headaches. These headaches are a sign that the medicine is working. If you have severe pain, talk with your doctor.

Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using this medication during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking this medication. This medication is pregnancy risk category C, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from lenitral (injection)?

Some common side effects may occur when using this drug, including:

  • Headache
  • Dizziness
  • Lightheadedness
  • Syncope
  • Vertigo
  • Drowsiness
  • Severe and prolonged headache
  • Cerebral ischemia
  • Hypotension
  • Angina increased
  • Paradoxical
  • Bradycardia
  • Tachycardia
  • Orthostatic hypotension
  • Blood pressure decreased
  • Facial flushing
  • Circulatory collapse
  • Cyanosis
  • Flushing
  • Heart rate increase
  • Nausea
  • Vomiting
  • Dry mouth
  • Heartburn
  • Halitosis
  • Dermatitis contact
  • Erythema
  • Pruritus
  • Irritation
  • Eczema
  • Urticaria
  • Allergic skin reactions
  • Rash
  • Asthenia
  • Weakness
  • Restlessness

If any of the following side effects occur while taking lenitral, check with your doctor immediately:

  • Bloating or swelling of the face, arms, hands, lower legs, or feet
  • Burning, crawling, itching, numbness, prickling, “pins and needles”, or tingling feelings
  • Difficult or labored breathing
  • Feeling faint, dizzy, or lightheadedness
  • Feeling of warmth or heat
  • Flushing or redness of the skin, especially on the face and neck
  • Rapid weight gain
  • Sweating
  • Tightness in the chest
  • Tingling of the hands or feet
  • Unusual weight gain or loss
  • Bluish-colored lips, fingernails, or palms
  • Dark urine
  • Fever
  • Pale skin
  • Rapid heart rate
  • Sore throat
  • Unusual bleeding or bruising
  • Unusual tiredness or weakness

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with lenitral (injection)?

Lenitral may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products may interact with this drug, including:

  • Avanafil
  • Riociguat
  • Sildenafil
  • Tadalafil
  • Vardenafil
  • Alteplase
  • Recombinant
  • Heparin
  • Acetylcysteine
  • Aspirin
  • Dihydroergotamine
  • Pancuronium

Does food or alcohol interact with lenitral (injection)?

Lenitral may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with lenitral (injection)?

Lenitral may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Especially, if you have:

  • Constrictive pericarditis (a heart disease)
  • Pericardial tamponade (a heart disease)
  • Restrictive cardiomyopathy (a heart disease)
  • Diabetes
  • Hypertrophic cardiomyopathy (a heart disease)
  • Hypotension (low blood pressure)
  • Hypovolemia (low amount of blood)

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using lenitral (injection).

What is the dose of lenitral (injection) for an adult?

Angina Pectoris

Intravenous solution:

The recommended dose is 5 mcg/min continuous IV infusion via non-absorptive tubing; increase by 5 mcg/min every 3 to 5 minutes as needed up to 20 mcg/min, then by 10 or 20 mcg/min if needed.

Myocardial Infarction

Intravenous solution:

The recommended dose is 5 mcg/min continuous IV infusion via non-absorptive tubing; increase by 5 mcg/min every 3 to 5 minutes as needed up to 20 mcg/min, then by 10 or 20 mcg/min if needed.

Hypertension

Intravenous solution:

The recommended dose is 5 mcg/min continuous IV infusion via non-absorptive tubing; increase by 5 mcg/min every 3 to 5 minutes as needed up to 20 mcg/min, then by 10 or 20 mcg/min if needed.

What is the dose of lenitral (injection) for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is lenitral (injection) available?

Lenitral is available in the following dosage forms and strengths:

  • Injection 100mcg/ml, 1mg/ml, 1,5 mg/ml

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

Symptoms of overdose are:

  • Bluish-colored lips, fingernails, or palms
  • Blurred or loss of vision
  • Bulging soft spot on the head of an infant
  • Change in consciousness
  • Change in the ability to see colors, especially blue or yellow
  • Cold, clammy skin
  • Dark urine
  • Difficulty breathing
  • Disturbed color perception
  • Dizziness or lightheadedness
  • Double vision
  • Fever
  • Flushed skin
  • Halos around lights
  • Headache, severe and throbbing
  • Increased sweating
  • Loss of appetite
  • Loss of consciousness
  • Night blindness
  • Overbright appearance of lights
  • Pale skin
  • Paralysis
  • Slow or irregular heartbeat
  • Sore throat
  • Tunnel vision
  • Unusual bleeding or bruising
  • Unusual tiredness or weakness

What should I do if I miss a dose?

If you miss a dose of lenitral, contact your doctor right away.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Review Date: March 25, 2017 | Last Modified: March 25, 2017

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