Generic Name: Lantus Brand Name(s): Generics only. No brands available.

Uses

What is Lantus® (insulin glargine) used for?

Lantus® is a man-made form of a hormone that is produced in the body. Insulin is a hormone that works by lowering levels of glucose (sugar) in the blood. Insulin glargine is a long-acting insulin that starts to work several hours after injection and keeps working evenly for 24 hours.

Lantus® is used to improve blood sugar control in adults and children with diabetes mellitus.

Lantus® is used to treat type 2 diabetes in adults.

Lantus® is also used to treat type 1 diabetes in adults and children who are at least 6 years old.

How should I take Lantus® (insulin glargine)?

Use Lantus® exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

The Toujeo brand of insulin glargine contains 3 times as much insulin per milliliter (mL) as the Lantus brand. There are 300 units of insulin in 1 mL of Toujeo, and 100 units in 1 mL of Lantus®.

If there are any changes in the brand, strength, or type of insulin you use, your dosage needs may change.

Insulin is injected under the skin. You will be shown how to use injections at home. Do not give yourself this medicine if you do not understand how to use the injection and properly dispose of used needles and syringes.

Lantus® must not be given with an insulin pump, or mixed with other insulins. Do not inject insulin glargine into a vein or a muscle.

Lantus® is usually injected once per day at the same time each day. You will be shown how to use injections at home. Do not give yourself this medicine if you do not understand how to use the injection and properly dispose of used needles and syringes.

Your care provider will show you the best places on your body to inject Lantus®. Use a different place each time you give an injection. Do not inject into the same place two times in a row.

If you use an injection pen, use only the injection pen that comes with Lantus®. Attach a new needle before each use. Do not transfer the insulin from the pen into a syringe.

Never share an injection pen or syringe with another person, even if the needle has been changed. Sharing these devices can allow infections or disease to pass from one person to another.

Use a disposable needle and syringe only once. Follow any state or local laws about throwing away used needles and syringes. Use a puncture-proof “sharps” disposal container (ask your pharmacist where to get one and how to throw it away). Keep this container out of the reach of children and pets.

Low blood sugar (hypoglycemia) can happen to everyone who has diabetes. Symptoms include headache, hunger, sweating, irritability, dizziness, nausea, fast heart rate, and feeling anxious or shaky. To quickly treat low blood sugar, always keep a fast-acting source of sugar with you such as fruit juice, hard candy, crackers, raisins, or non-diet soda.

Your doctor can prescribe a glucagon emergency injection kit to use in case you have severe hypoglycemia and cannot eat or drink. Be sure your family and close friends know how to give you this injection in an emergency.

Also watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination, blurred vision, headache, and tiredness.

Blood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your insulin dose or schedule.

Lantus® is only part of a treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Follow your doctor’s instructions very closely.

How do I store Lantus® (insulin glargine)?

Lantus® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Lantus® in the bathroom or the freezer. There may be different brands of Lantus® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Lantus® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Lantus® (insulin glargine)?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of Lantus® or other medications.
  • You have any other illnesses, disorders, or medical conditions.
  • You are having an episode of hypoglycemia (low blood sugar).

Lantus® should not be given to a child younger than 6 years old. Lantus® should not be used to treat type 2 diabetes in a child of any age.

To make sure Lantus® is safe for you, tell your doctor if you have:

  • Liver or kidney disease
  • Low levels of potassium in your blood (hypokalemia)
  • Diabetic ketoacidosis (call your doctor for treatment)

Tell your doctor if you also take pioglitazone or rosiglitazone (sometimes contained in combinations with glimepiride or metformin). Taking certain oral diabetes medicines while you are using insulin may increase your risk of serious heart problems.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using Lantus® during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Lantus®. Lantus® is pregnancy risk category C, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from Lantus® (insulin glargine)?

Get emergency medical help if you have signs of an allergy reaction to Lantus®: redness or swelling where an injection was given, itchy skin rash over the entire body, trouble breathing, fast heartbeats, feeling like you might pass out, or swelling in your tongue or throat.

Call your doctor at once if you have:

  • Fluid retention – weight gain, swelling in your hands or feet, feeling short of breath
  • Low potassium – leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling

Common side effects may include:

  • Low blood sugar
  • Itching, mild skin rash
  • Thickening or hollowing of the skin where you injected the medicine

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Lantus® (insulin glargine)?

Lantus® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Lantus® (insulin glargine)?

Lantus® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Lantus® (insulin glargine)?

Lantus® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Health conditions that may interact with this drug are:

  • Liver or kidney disease
  • Low levels of potassium in your blood (hypokalemia)
  • Diabetic ketoacidosis (call your doctor for treatment)

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Lantus® (insulin glargine).

What is the dose of Lantus® (insulin glargine) for an adult?

Type 1 Diabetes:

Lantus® must be used concomitantly with short-acting insulin.

The recommended starting dose of Lantus® in patients with type 1 diabetes should be approximately one-third of the total daily insulin requirements.

Short-acting, premeal insulin should be used to satisfy the remainder of the daily insulin requirements.

Type 2 Diabetes:

The recommended starting dose of Lantus® in patients with type 2 diabetes who are not currently treated with insulin is 0.2 units/kg or up to 10 units once daily.

One may need to adjust the amount and timing of short- or rapid-acting insulins and dosages of any oral anti-diabetic drugs.

What is the dose of Lantus® (insulin glargine) for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Lantus® (insulin glargine) available?

Lantus® is available in the following dosage forms and strengths:

  • Injection, solution: insulin glargine 100[iU] in 1Ml

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Lantus®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: September 2, 2017 | Last Modified: September 2, 2017