Generic Name: Ketotifen Brand Name(s): .

Uses

What is Ketotifen used for?

Ketotifen is used to prevent and treat itching of the eyes caused by allergies (allergic/seasonal conjunctivitis). Ketotifen is an antihistamine for the eye that treats allergic symptoms by blocking a certain natural substance (histamine). It is also a mast cell stabilizer that prevents allergic reactions by reducing the release of natural substances that cause an allergic reaction.

How should I take Ketotifen?

If you are using the over-the-counter product, read all directions on the product package before using this medication. If your doctor has prescribed this medication, use it exactly as directed.

Apply 1 drop to the affected eye(s), usually twice a day (every 8 to 12 hours) or as directed by the package instructions or your doctor.

Dosage is based on your medical condition and response to treatment.

To apply eye drops, wash your hands first. To avoid contamination, do not touch the dropper tip or let it touch your eye or any other surface.

Ask your doctor if you can wear contact lenses while you are being treated with this medication. If your doctor says you may continue wearing them, remove them before using the eye drops, and wait at least 10 minutes after each dose before putting in your lenses. Do not use this medication to treat irritation from contact lens wear. Consult your doctor about the use of contact lenses when the eyes are red or irritated.

Tilt your head back, look upward, and pull down the lower eyelid to make a pouch. Hold the dropper directly over your eye and apply 1 drop in the lower eyelid. Look downward and gently close your eyes for 1 to 2 minutes. Place one finger at the corner of your eye (near the nose) and apply gentle pressure. This will prevent the medication from draining out. Try not to blink and do not rub your eye.

Do not rinse the dropper. Replace the dropper cap after each use, and keep the bottle tightly closed.

If you are using another kind of eye medication (drops or ointment), wait at least 5 minutes before applying it. Apply eye drops before eye ointments to allow the eye drops to enter the eye.

If your doctor has prescribed this medication, use it regularly in order to get the most benefit from it. To help you remember, use it at the same times each day. Continue to use this medication as prescribed until pollen season is over or you are no longer exposed to the allergic substance, even when allergic symptoms disappear or improve.

If your condition persists or worsens, if you develop new symptoms, or if you think you have a serious medical problem, seek immediate medical attention. If you are treating yourself with nonprescription ketotifen, consult your doctor if your itching worsens or lasts more than 72 hours. You may need a different medication.

How do I store Ketotifen?

Ketotifen is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Ketotifen in the bathroom or the freezer. There may be different brands of Ketotifen that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Ketotifen down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Ketotifen?

Before using ketotifen, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as the preservative benzalkonium chloride in the multi-dose container), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: eye problems (e.g., glaucoma).

After you apply this drug, your vision may become temporarily blurred. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely.

Do not use this medication in children younger than 3 years unless directed by the doctor.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.

Is it safe during pregnancy or breast-feeding?

There are no adequate studies in women for determining risk when using this Ketotifen during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Ketotifen. Ketotifen is pregnancy risk category N according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk,
  • B=No risk in some studies,
  • C=There may be some risk,
  • D=Positive evidence of risk,
  • X=Contraindicated,
  • N=Unknown

Side effects

What side effects can occur from Ketotifen?

Burning/stinging/irritation of the eye, headache, stuffy/runny nose, bad taste in your mouth, and increased sensitivity to light may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if any of these unlikely but serious side effects occur: dry eyes, eye pain, increased redness/swelling of the eye, vision problems.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Ketotifen?

Ketotifen may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Ketotifen?

Ketotifen may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Ketotifen?

Ketotifen may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using this Ketotifen.

What is the dose of Ketotifen for an adult?

Usual Adult Dose for Allergic Conjunctivitis

Instill 1 drop in the affected eye(s) 2 times a day

Comments: May administer eye drops every 8 to 12 hours, but should not administer more than twice a day.

Use: For the treatment of itching related to pollen, ragweed, grass, animal hair and dander.

Renal Dose Adjustments

No adjustment recommended

Liver Dose Adjustments

No adjustment recommended

Other Comments

Administration advice:

-For ophthalmic use only

-Remove soft contact lens prior to treatment; may reinsert lenses 10 minutes after eye drop administration.

Storage:

-Do not use if solution changes color or becomes cloudy.

-Replace cap to bottle after each use.

Patient advice:

-Patients should be instructed not to wear a contact lens if eyes are red.

-Patients should be instructed not to touch bottle tip to eyes, hands, or any other surface in order to prevent contamination of the bottle.

-Patients should be instructed to notify their healthcare professional if they experience eye pain, changes in vision, redness of the eye, or if itching does not improve after 72 hours.

What is the dose of Ketotifen for a child?

Usual Pediatric Dose for Allergic Conjunctivitis

Age: 3 years and older

Instill 1 drop in the affected eye(s) 2 times a day

Comments: May administer eye drops every 8 to 12 hours, but should not administer more than twice a day.

Use: For the treatment of itching related to pollen, ragweed, grass, animal hair and dander.

Precautions

Safety and efficacy have not been established in patients younger than 3 years.

How is Ketotifen available?

Ketotifen is available in the following dosage forms and strengths:

  • Ophthalmic Solution

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Ketotifen, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: March 5, 2018 | Last Modified: March 5, 2018