Kefadim

By Medically reviewed by hellodoktor

Generic Name: Kefadim Brand Name(s): Generics only. No brands available.

Uses

What is Kefadim® (ceftazidime) used for?

Kefadim® is in a class of medications called cephalosporin antibiotics. It works by killing bacteria.

Kefadim® is used to treat certain infections caused by bacteria including:

  • Pneumonia
  • Other lower respiratory tract (lung) infections
  • Meningitis (infection of the membranes that surround the brain and spinal cord)
  • Other brain and spinal cord infections
  • Abdominal (stomach area)
  • Skin
  • Blood
  • Bone
  • Joint
  • Female genital tract
  • Urinary tract infections

How should I take Kefadim® (ceftazidime)?

Kefadim® injection comes as a powder to be mixed with liquid and given intravenously (into a vein) or intramuscularly (into a muscle). It is also available as a premixed product to be injected intravenously. It is usually given every 8 or 12 hours until 2 days after all signs and symptoms of the infection have disappeared.

You may receive Kefadim® injection in a hospital or you may administer the medication at home.

If you will be receiving Kefadim® injection at home, your healthcare provider will show you how to use the medication. Be sure that you understand these directions, and ask your healthcare provider if you have any questions.

You should begin to feel better during the first few days of treatment with Kefadim® injection. If your symptoms do not improve or get worse, call your doctor.

Take Kefadim® injection until you finish the prescription, even if you feel better. If you stop taking Kefadim® injection too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.

How do I store Kefadim® (ceftazidime)?

Kefadim® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Kefadim® in the bathroom or the freezer. There may be different brands of Kefadim® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Kefadim® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Kefadim® (ceftazidime)?

Before taking Kefadim® injection, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of Kefadim® or other medications.
  • You have any other illnesses, disorders, or medical conditions.

You should know that Kefadim® decreases the effectiveness of some oral contraceptives (‘birth control pills). You will need to use another form of birth control while taking this medication. Talk to your doctor about other ways to prevent pregnancy while you are taking this medication.

Is it safe during pregnancy or breastfeeding?

There isn’t enough information about the safety of using Kefadim® during pregnancy and breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Kefadim®.

Side effects

What side effects can occur from Kefadim® (ceftazidime)?

When using this drug, tell your doctor if you notice these side effects:

  • Pain
  • Redness
  • Swelling
  • Bleeding
  • Diarrhea

Some side effects can be serious. If you experience any of these symptoms, stop taking Kefadim® and call your doctor immediately or get emergency medical treatment:

  • Watery or bloody stools
  • Stomach cramps
  • Fever
  • Swelling of the face, throat, tongue, lips, and eyes
  • Difficulty swallowing or breathing
  • Hoarseness
  • Rash
  • Itching
  • Peeling, blistering, or shedding skin
  • Seizures
  • A return of fever, sore throat, chills, or other signs of infection

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Kefadim® (ceftazidime)?

Kefadim® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products may interact with your drug, including:

  • Chloramphenicol
  • Aminoglycoside
  • Cefaclor
  • Cefadroxil
  • Cefazolin (Ancef, Kefzol)
  • Cefdinir
  • Cefditoren (Spectracef)
  • Cefepime (Maxipime)
  • Cefixime (Suprax)
  • Cefotaxime (Claforan)
  • Cefotetan
  • Cefoxitin (Mefoxin)
  • Cefpodoxime
  • Cefprozil
  • Ceftaroline (Teflaro)
  • Ceftibuten (Cedax)
  • Ceftriaxone (Rocephin)
  • Cefuroxime (Zinacef)
  • Cephalexin (Keflex)
  • Penicillin antibiotics
  • Amikacin
  • Chloramphenicol
  • Gentamicin
  • Kanamycin
  • Neomycin (Neo-Fradin)
  • Streptomycin
  • Tobramycin

Does food or alcohol interact with Kefadim® (ceftazidime)?

Kefadim® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Kefadim® (ceftazidime)?

Kefadim® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

These health conditions may include:

  • A recent surgery or trauma
  • Diabetes
  • Cancer
  • Heart failure
  • Gastrointestinal disease (GI; affecting the stomach or intestines)
  • Colitis (condition that causes swelling in the lining of the colon [large intestine])
  • Liver or kidney disease

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Kefadim® (ceftazidime).

What is the dose of Kefadim® (ceftazidime) for an adult?

Bacteremia

The recommended dose is 2 g IV every 8 hours for 14 days, depending on the nature and severity of the infection.

Meningitis

The recommended dose is 2 g IV every 8 hours for 14 days, depending on the nature and severity of the infection.

Sepsis

The recommended dose is 2 g IV every 8 hours for 14 days, depending on the nature and severity of the infection.

Endocarditis

The recommended dose is 2 g IV every 8 hours.

Endometritis

The recommended dose is 2 g IV or IM every 8 hours.

Febrile Neutropenia

The recommended dose is 2 g IV every 8 hours.

Joint Infection

The recommended dose is 2 g IV every 8 hours.

Intraabdominal Infection

The recommended dose is 2 g IV every 8 hours for 7 to 14 days, depending on the nature and severity of the infection.

What is the dose of Kefadim® (ceftazidime) for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Kefadim® (ceftazidime) available?

Kefadim® is available in the following dosage forms and strengths:

  • Injectable powder 1g

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Kefadim®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Review Date: May 10, 2017 | Last Modified: September 13, 2019

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