Generic Name: Kanamycin Meiji Brand Name(s): Generics only. No brands available.

Uses

What is kanamycin meiji (kanamycin sulfate) used for?

Kanamycin meiji is commonly used for serious infection caused by Escherichia coli, Klebsiella pneumonia, Enterobacter aerogenes, Proteus vulgaris, such as:

Kanamycin may be used for other purposes, ask your doctor for more information.

How should I take kanamycin meiji (kanamycin sulfate)?

Kanamycin sulfate is dissolved in water for injection. The amount of solvent to be added to 0.5g (base), 1g (base) or 2g (base) vial to obtain the desired concentrations are shown in the following table. The solution is so stable as to retain its potency at room temperature, but is preferable to use soon after preparation.

The solutions of 150 to 400 mg (base) per ml are usually employed.

How do I store kanamycin meiji (kanamycin sulfate)?

Kanamycin meiji is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store kanamycin meiji in the bathroom or the freezer. There may be different brands of kanamycin meiji that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush kanamycin meiji down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using kanamycin meiji (kanamycin sulfate)?

Before using this drug, there is some important information that you may notice:

  • Patients receiving the drug should be carefully observed for sign of eight nerve damage. It is desirable to discontinue the treatment immediately when the toxic effects appear. If administration of the drug is unavoidable, the drug should he administered under careful observation. Observation should be done to renal function, audiogram, before and during treatment to the patient with renal damage.
  • Elderly patient, patient with tinnitus or vertigo and patient used ototoxic before, should be carefully observed due to possibility of eight nerve damage.
  • In pregnancy, patient should be used with caution because of the possibility of inducing a damage to the eight nerve of a newborn.
  • The drug should be discontinued if a hypersensitivity reaction occurs. In patients with hypersensitive to one of aminoglycoside group, such as
    Fradiomycin, Streptomycin, dihydrostreptomycin, Kanamycin, Gentamycin, the drug should be avoided.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using kanamycin meiji during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking kanamycin meiji. Kanamycin meiji is pregnancy risk category D, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from kanamycin meiji (kanamycin sulfate)?

Some side effects can happen when using this drug, such as:

  • Using kanamycin may cause impairment of the auditory portion of the eight nerve (mainly cochlear function damage) with signs such as tinnitus, hearing difficulty and vertigo.
  • Nephrotoxic effect may be seen in some patients. If the sign of renal damage occurs, the drug should be discontinued.
  • Administration of the drug may cause transient headache and numbness of lips, neurotoxicity, nephrotoxicity, eosinophilia, rash, pruritis, fever, paresthesia.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with kanamycin meiji (kanamycin sulfate)?

Kanamycin meiji may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products that may interact with this drug including:

  • Blood substitute such as dextran and sodium alginate because the possibility of the intensifying affects these nephrotoxic drugs.
  • Anesthetics or muscular relaxant since the combinations with such drugs may cause respiratory depression due curare action.

Does food or alcohol interact with kanamycin meiji (kanamycin sulfate)?

Kanamycin meiji may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with kanamycin meiji (kanamycin sulfate)?

Kanamycin meiji may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using kanamycin meiji (kanamycin sulfate).

What is the dose of kanamycin meiji (kanamycin sulfate) for an adult?

Acute infections:

1-2 g daily (15 mg – base) per kg body weight, per day is injected in 1 or 2 divided doses.

Tuberculosis:

The recommended dose is 1 g daily 3 times weekly or 2 g daily 2 times weekly.

Gonorrhea:

The recommended dose is 2g as single dose by IM injection.

Above dosage should be adjusted according to patient condition and disease.

What is the dose of kanamycin meiji (kanamycin sulfate) for a child?

Acute infections:

15 mg (base) per kg body weight, per day is injected in 1 or 2 divided doses.

Above dosage should be adjusted according to patient condition and disease.

How is kanamycin meiji (kanamycin sulfate) available?

Kanamycin meiji is available in the following dosage forms and strengths:

  • 5 g (Base) / vial
  • 1 g (Base) / vial
  • 2 g (Base) / vial

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of kanamycin Meiji, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

 

Sources

Review Date: March 11, 2017 | Last Modified: March 11, 2017