Isordil

By Medically reviewed by hellodoktor

Generic Name: Isordil Brand Name(s): Isordil and Isordil.

Uses

What is Isordil® (isosorbide dinitrate) used for?

Isordil® is commonly used to treat or prevent attacks of chest pain (angina).

How should I take Isordil® (isosorbide dinitrate)?

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

You should take this medicine first thing in the morning and follow the same schedule each day. This medicine works best if you have a “drug-free” period of time every day when you do not take it.

Your doctor will schedule your doses during the day to allow for a drug-free time. Follow the schedule of dosing carefully so the medicine will work properly.

How do I store Isordil® (isosorbide dinitrate)?

Isordil® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Isordil® in the bathroom or the freezer. There may be different brands of Isordil® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Isordil® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Isordil® (isosorbide dinitrate)?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of Isordil® or other medications.
  • You have any other illnesses, disorders, or medical conditions.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using this medication during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking this medication. This medication is pregnancy risk category C, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from Isordil® (isosorbide dinitrate)?

Side effects may occur while using this drug, such as:

  • Rash
  • Hives
  • Itching
  • Difficulty breathing
  • Tightness in the chest
  • Swelling of the mouth, face, lips, or tongue
  • Fainting
  • Fast or slow heartbeat
  • Nausea
  • New or worsening chest pain
  • Vomiting

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Isordil® (isosorbide dinitrate)?

Isordil® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products that may interact with this drug, such as:

  • Avanafil
  • Riociguat
  • Sildenafil
  • Tadalafil
  • Vardenafil

Does food or alcohol interact with Isordil® (isosorbide dinitrate)?

Isordil® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Isordil® (isosorbide dinitrate)?

Isordil® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

These health conditions are:

  • Bleeding in the brain
  • A recent head trauma
  • An overactive thyroid
  • Heart problems (e.g., heart failure, cardiomyopathy, history of heart attack)
  • Anemia (a low red blood cell count)

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Isordil® (isosorbide dinitrate).

What is the dose of Isordil® (isosorbide dinitrate) for an adult?

The usual starting dose of Isordil® is 5 mg to 20 mg, two or three times daily.

For maintenance therapy, 10 mg to 40 mg, two or three times daily is recommended. Some patients may require higher doses.

What is the dose of Isordil® (isosorbide dinitrate) for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Isordil® (isosorbide dinitrate) available?

Isordil® is available in the following dosage forms and strengths:

  • Tablet 5mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Isordil®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: June 16, 2017 | Last Modified: September 13, 2019

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