Generic Name: Imodium A-D Brand Name(s): Imodium A-D.

Uses

What is Imodium A-D® used for?

Imodium A-D® is commonly used to slow the rhythm of digestion so that the small intestines have more time to absorb fluid and nutrients from the foods you eat.

Imodium A-D® is used to treat diarrhea.

Imodium A-D® is also used to reduce the amount of stool in people who have an ileostomy (re-routing of the bowel through a surgical opening in the stomach).

How should I take Imodium A-D®?

Use Imodium A-D® exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

For adults, Imodium is usually taken as a single dose of 4 milligrams (mg) at the first sign of diarrhea, and again at a dose of 2 mg if diarrhea comes back. For children, the correct dose depends on the child’s age.

Do not take more than the recommended dose of this medicine. Misuse of loperamide can cause serious heart problems that could be fatal. Follow all dosing instructions very carefully.

If you take Imodium A-D® without a prescription (over-the-counter), do not take more 8 mg in 24 hours. If your doctor has prescribed this medicine, do not take more than 16 mg per day.

The Imodium A-D® chewable tablet must be chewed before swallowing.

Shake the oral suspension (liquid) well just before you measure a dose. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

Take Imodium A-D® with a full glass of water. Drink plenty of liquids while you are taking this medicine, to keep from getting dehydrated.

How do I store Imodium A-D®?

Imodium A-D® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Imodium A-D® in the bathroom or the freezer. There may be different brands of Imodium A-D® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Imodium A-D® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Imodium A-D®?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of Imodium A-D® or other medications.
  • You have any other illnesses, disorders, or medical conditions.

This medicine can cause serious breathing problems and heart problems in a child. Imodium should not be given to a child younger than 2 years old. Do not give this medicine to any child or teenager without the advice of a doctor.

Ask a doctor or pharmacist if it is safe for you to take this medicine if you have:

  • A fever
  • Mucus in your stools
  • AIDS (acquired immunodeficiency syndrome)
  • A history of liver disease
  • If you are taking an antibiotic

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using Imodium A-D® during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Imodium A-D®. Imodium A-D® is pregnancy risk category C, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from Imodium A-D®?

Get emergency medical help if you have signs of an allergic reaction to Imodium A-D®: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop taking Imodium A-D® and call your doctor at once if you have:

  • Headache with chest pain and severe dizziness
  • A light-headed feeling, like you might pass out
  • Fast or pounding heartbeats
  • Stomach pain or bloating
  • Ongoing or worsening diarrhea
  • Diarrhea that is watery or bloody
  • Severe skin reaction – fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling

Common side effects may include:

  • Dizziness, drowsiness
  • Dry mouth
  • Constipation
  • Stomach discomfort
  • Nausea and vomiting

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Imodium A-D®?

Imodium A-D® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products that may interact with this drug are:

  • Gemfibrozil, ritonavir
  • Stomach acid reducers – cimetidine, ranitidine
  • Anagrelide, cilostazol, donepezil, fluconazole, methadone, ondansetron
  • An antibiotic or antifungal medicine – azithromycin, ciprofloxacin, clarithromycin, erythromycin, fluconazole, itraconazole, ketoconazole, levofloxacin, moxifloxacin, pentamidine, telithromycin
  • Cancer medicine – arsenic trioxide, oxaliplatin, vandetanib
  • An antidepressant – citalopram, escitalopram
  • Anti-malaria medication – chloroquine, halofantrine, quinine
  • Heart rhythm medicine – amiodarone, disopyramide, dofetilide, dronedarone, flecainide, ibutilide, procainamide, quinidine, sotalol
  • medicine to treat a psychiatric disorder – chlorpromazine, droperidol, haloperidol, pimozide, thioridazine

Does food or alcohol interact with Imodium A-D®?

Imodium A-D® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Imodium A-D®?

Imodium A-D® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Health conditions that may interact with this drug are:

  • Stomach pain without diarrhea
  • Diarrhea with a high fever
  • Ulcerative colitis
  • Stools that are bloody, black, or tarry
  • Diarrhea that is caused by a bacterial infection
  • Diarrhea caused by taking an antibiotic (Clostridium difficile)

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Imodium A-D®.

What is the dose of Imodium A-D® for an adult?

Usual Adult Dose for Diarrhea — Acute:

Tablets, capsules, and liquid:

  • Initial: 4 mg orally after the first loose stool, then
  • Maintenance: 2 mg after each loose stool, not to exceed 16 mg in any 24-hour period. Clinical improvement is usually observed within 48 hours.

Chewable tablets:

  • Initial: 4 mg after the first loose stool, then
  • Maintenance: 2 mg after each subsequent loose stool, but not exceeding 8 mg in 24 hours.

Usual Adult Dose for Diarrhea — Chronic:

Tablets, capsules, and liquid:

  • Initial: 4 mg orally once followed by 2 mg orally after each loose stool, not to exceed 16 mg in any 24-hour period.
  • Maintenance: The average daily maintenance dosage is 4 to 8 mg. Clinical improvement is usually observed within 10 days. If clinical improvement is not observed at a maximum dosage of 16 mg for duration of 10 days, symptoms are unlikely to be controlled by further administration.

What is the dose of Imodium A-D® for a child?

Usual Pediatric Dose for Diarrhea — Acute:

2 to 6 years (13 to 20 kg):

Liquid formulation only to be used in this age group.

  • Initial: 1 mg orally 3 times a day for the first day, then
  • Maintenance: 0.1 mg/kg/dose after each loose stool, but not exceeding initial dose.

6 to 8 years (20 to 30 kg):

Tablets, capsules, and liquid:

  • Initial: 2 mg orally twice a day for the first day, then
  • Maintenance: 0.1 mg/kg/dose after each loose stool, but not exceeding initial dose.

Chewable tablets:

  • Initial: 2 mg orally after the first loose stool, then
  • Maintenance: 1 mg orally after each subsequent loose stool, but not exceeding 4 mg in 24 hours.

8 to 12 years (greater than 30 kg):

Tablets, capsules, and liquid:

  • Initial: 2 mg orally 3 times a day for the first day, then
  • Maintenance: 0.1 mg/kg/dose after each loose stool, but not exceeding initial dose.

Chewable tablets:

  • Initial: 2 mg orally after the first loose stool, then
  • Maintenance: 1 mg orally after each subsequent loose stool, but not exceeding 6 mg in 24 hours.

12 to 18 years:

Tablets, chewable tablets, capsules, and liquid:

  • Initial: 4 mg after the first loose stool, then
  • Maintenance: 2 mg after each subsequent loose stool, but not exceeding 8 mg in 24 hours.

Usual Pediatric Dose for Diarrhea — Chronic:

less than 2 years:

Therapeutic dose for the treatment of chronic diarrhea has not been established for this patient population.

How is Imodium A-D® available?

Imodium A-D® is available in the following dosage forms and strengths:

  • Tablet
  • Capsule
  • Liquid

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Imodium A-D®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: November 9, 2017 | Last Modified: November 9, 2017

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