Homatropine drops


Generic Name: Homatropine drops Brand Name(s): Generics only. No brands available.


What is homatropine drops used for?

Homatropine drops are an anticholinergic agent. It works by blocking the chemical acetylcholine, which relaxes the ciliary muscle of the eye and causes the pupil to dilate.

Homatropine drops are commonly used for widening (dilating) the pupils for an eye exam or treating certain inflammatory conditions of the eye.

It may also be used for other conditions as determined by your doctor.

How should I take homatropine drops?

Use homatropine drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

To use homatropine drops in the eye, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eyelid for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean, dry tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.

To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed.

How do I store homatropine drops?

Homatropine drops is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store homatropine drops in the bathroom or the freezer. There may be different brands of homatropine drops that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush homatropine drops down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using homatropine drops?

Before using homatropine drops, tell your doctor if:

  • You are allergic to any ingredient in homatropine drops.
  • You have glaucoma or are at risk for glaucoma.
  • You are pregnant, planning to become pregnant, or are breastfeeding.
  • You are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement.
  • You have allergies to medicines, foods, or other substances.

Homatropine drops may cause harm if it is swallowed. If you may have taken it by mouth, contact your poison control center or emergency room right away.

Homatropine drops may cause blurred vision. Use homatropine drops with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

Homatropine drops may make your eyes more sensitive to sunlight. It may help to wear sunglasses.

Lab tests, including eye exams, may be performed while you use homatropine drops. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

Use homatropine drops with caution in the elderly; they may be more sensitive to its effects.

Homatropine drops should be used with extreme caution in children; safety and effectiveness in children have not been confirmed.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using homatropine drops during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking homatropine drops. Homatropine drops are pregnancy risk category C, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from homatropine drops?

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most common side effects persist or become bothersome:

  • Blurred vision
  • Eye itching, burning or stinging
  • Irritation at the application site

Seek medical attention right away if any of these severe side effects occur:

  • Rash
  • Hives
  • Itching
  • Difficulty breathing
  • Tightness in the chest
  • Swelling of the mouth, face, lips, or tongue
  • Difficulty urinating
  • Dry mouth
  • Eye pain
  • Fever
  • Flushing or dryness of the skin
  • Irregular or rapid heartbeat
  • Unsteadiness on your feet

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with homatropine drops?

Homatropine drops may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Especially if you are taking antihistamines (e.g., diphenhydramine), medicine for Parkinson disease (e.g., benztropine), or tricyclic antidepressants (e.g., amitriptyline), because they may increase the risk of homatropine drops’s side effects.

Does food or alcohol interact with homatropine drops?

Homatropine drops may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with homatropine drops?

Homatropine drops may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

These health conditions may include:

  • Numbness due to nerve damage
  • A blockage of the bladder
  • Prostate problems
  • Difficulty urinating
  • Cornea problems
  • Down syndrome


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using homatropine drops.

What is the dose of homatropine drops for an adult?

Mydriasis and cycloplegia for refraction

Instill 1 or 2 drops of the 2% or 5% solution in the affected eye(s). May be repeated in 5 or 10 min if necessary.


Instill 1 or 2 drops of the 2% or 5% solution into the affected eye(s) up to every 3 or 4 h.

What is the dose of homatropine drops for a child?

Mydriasis and cycloplegia for refraction

Instill 1 or 2 drops of the 2% solution only in the affected eye(s). May be repeated in 5 or 10 min if necessary.


Instill 1 or 2 drops of the 2% solution only into the affected eye(s) up to every 3 or 4 h.

Use cautiously in infants and small children. Safety and efficacy of the 5% solution have not been established.

How is homatropine drops available?

Homatropine drops is available in the following dosage forms and strengths:

  • Solution, ophthalmic 2%
  • Solution, ophthalmic 5%

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of homatropine drops, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

msBahasa Malaysia

Review Date: April 1, 2017 | Last Modified: April 1, 2017

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