Glyceryl trinitrate

By Medically reviewed by hellodoktor

Generic Name: Glyceryl trinitrate Brand Name(s): Glyceryl trinitrate.

Uses

What is glyceryl trinitrate used for?

Glyceryl trinitrate is a nitrate vasodilator, commonly used for:

  • Prevent or stop chest pain caused by angina pectoris.
  • Stop spasms in the blood vessels of the heart.

How should I take glyceryl trinitrate?

For orally taken form, you should:

  • Take glyceryl trinitrate by mouth as directed by your doctor concerning: dose, schedule.
  • Read the label carefully before using glyceryl trinitrate.
  • Consult your doctor for any information on the label that you do not clearly understand.

How do I store glyceryl trinitrate?

Glyceryl trinitrate is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store glyceryl trinitrate in the bathroom or the freezer. There may be different brands of glyceryl trinitrate that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush glyceryl trinitrate down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using glyceryl trinitrate?

Before using glyceryl trinitrate, tell your doctor if:

  • You have allergic reaction to glyceryl trinitrate, excipients using for dosage form containing glyceryl trinitrate.
  • You have allergic reaction to any other medicines, foods, dyes, preservatives, or animals.
  • You have used any other health conditions, drugs that have a risk of interaction with glyceryl trinitrate.

Is it safe during pregnancy or breastfeeding?

There isn’t enough information about the safety of using glyceryl trinitrate during pregnancy and breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking glyceryl trinitrate.

Side effects

What side effects can occur from glyceryl trinitrate?

As taking others medicines, taking glyceryl trinitrate can cause some side effects. Most of them are rarely occurring and do not need any supplementary treatment. However It is always important for you to consult your doctor if you have any problem after taking this medicine.

Some of side effects are:

  • Worsening of angina symptoms
  • Chest pains
  • Hypoxaemia (difficulty breathing, increased rate of breathing)
  • Methaemoglobinaemia (breathing problems, headache, tiredness)
  • Difficulty breathing
  • Blue colouring of the lips, fingers or toes (cyanosis)
  • Rapid (tachycardia) or slowed (bradycardia) heartbeat
  • Blindness in one eye
  • Cerebral ischaemia which may cause weakness in one arm or leg, or weakness in one entire side of the body
  • Difficulty speaking
  • Slurred speech
  • Loss of coordination
  • Loss of consciousness
  • Throbbing headache
  • Spinning sensation
  • Fall in blood pressure when seated or standing up
  • Dizziness
  • Drowsiness
  • Weakness
  • Pain around the eye
  • Changes in vision

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with glyceryl trinitrate?

Glyceryl trinitrate may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval. Products may interact with this drug, such as:

  • Sildenafil (viagra), tadalafil (cialis) or vardenafil (levitra)
  • Heparin
  • N-acetylcysteine
  • Long acting nitrates (isosorbide dinitrate, isosorbide mononitrate)
  • High blood pressure medicines
  • Amitriptyline
  • Disopyramide
  • Atropine
  • Propantheline
  • Tricyclic antidepressants
  • Apomorphine
  • Ergot alkaloids

Does food or alcohol interact with glyceryl trinitrate?

Glyceryl trinitrate may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with glyceryl trinitrate?

Glyceryl trinitrate may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

These health conditions are:

  • Severe liver or kidney problems
  • An under active thyroid gland
  • A recent heart attack
  • Low body temperature (hypothermia)
  • Poor nutrition (due to an unbalanced diet or digestion problems)
  • Abnormally low levels of oxygen in the blood (hypoxaemia)
  • Low blood pressure
  • Low blood volume
  • Narrowing of heart valves
  • Inflammation of the heart
  • Fluid around the heart or heart failure
  • Cerebrovascular disease

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using glyceryl trinitrate.

What is the dose of glyceryl trinitrate for an adult?

Consult your doctor for information about dose of glyceryl trinitrate.

Recommended doses in some cases are listed below:

Angina pectoris

  • One tablet should be placed under the tongue and allowed to dissolve slowly. Repeated after 5 minutes if symptoms are not relieved.
  • Take the tablets sat down to reduce possible fainting or low blood pressure.

What is the dose of glyceryl trinitrate for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is glyceryl trinitrate available?

Glyceryl Trinitrate is available in the following dosage forms and strengths:

  • 300, 500, 600 microgram sublingual tablet

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of glyceryl trinitrate, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: February 11, 2017 | Last Modified: September 12, 2019

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