Ezetimibe + Atorvastatin

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Generic Name: Ezetimibe + Atorvastatin Brand Name(s): Generics only. No brands available.

Uses

What is Ezetimibe + Atorvastatin used for?

Ezetimibe + Atorvastatin is commonly used along with a proper diet to help lower “bad” cholesterol and fats (such as LDL, triglycerides) and raise “good” cholesterol (HDL) in the blood. Ezetimibe works by reducing the amount of cholesterol your body absorbs from your diet. Atorvastatin belongs to a group of drugs known as “statins.” It works by reducing the amount of cholesterol made by the liver.

In addition to eating a proper diet (such as a low-cholesterol/low-fat diet), other lifestyle changes that may help this medication work better include exercising, losing weight if overweight, and stopping smoking. Consult your doctor for more details.

Lowering “bad” cholesterol and triglycerides and raising “good” cholesterol decreases the risk of heart disease and helps prevent strokes and heart attacks.

How should I take Ezetimibe + Atorvastatin?

Take this medication by mouth with or without food as directed by your doctor, usually once daily.

The manufacturer directs not to crush, dissolve, or chew the tablet before taking it. However, many similar drugs (immediate-release tablets) can be crushed, dissolved, or chewed. Follow your doctor’s directions on how to take this medication.

If you are taking a bile acid sequestrant (such as cholestyramine or colestipol), take this product at least 2 hours before or at least 4 hours after taking the bile acid sequestrant. These medications may bind to ezetimibe/atorvastatin, preventing your body from fully absorbing the drug.

Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. It is important to continue taking this medication even if you feel well. Most people with high cholesterol or triglycerides do not feel sick.

It is very important to continue to follow your doctor’s advice about diet and exercise. It may take up to 4 weeks before you get the full benefit of this product.

How do I store Ezetimibe + Atorvastatin?

Ezetimibe + Atorvastatin is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Ezetimibe + Atorvastatin in the bathroom or the freezer. There may be different brands of Ezetimibe + Atorvastatin that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Ezetimibe + Atorvastatin down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Ezetimibe + Atorvastatin?

Before taking this product, tell your doctor or pharmacist if you are allergic to ezetimibe or atorvastatin; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, alcohol use.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Limit alcoholic beverages. Daily use of alcohol may increase your risk for liver problems, especially when combined with this product. Ask your doctor or pharmacist for more information.

Older adults may be more sensitive to the side effects of this drug, especially muscle problems.

This medication must not be used during pregnancy. Atorvastatin may harm an unborn baby. Therefore, it is important to prevent pregnancy while taking this medication. Consult your doctor for more details and to discuss the use of reliable forms of birth control (such as condoms, birth control pills) while taking this medication. If you become pregnant or think you may be pregnant, tell your doctor right away.

It is unknown if this medication passes into breast milk. Because of the possible risk to the infant, breast-feeding while using this product is not recommended. Consult your doctor before breast-feeding.

Is it safe during pregnancy or breast-feeding?

There are no adequate studies in women for determining risk when using this Ezetimibe + Atorvastatin during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Ezetimibe + Atorvastatin. Ezetimibe + Atorvastatin is pregnancy risk category X according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk,
  • B=No risk in some studies,
  • C=There may be some risk,
  • D=Positive evidence of risk,
  • X=Contraindicated,
  • N=Unknown

Side effects

What side effects can occur from Ezetimibe + Atorvastatin?

A very small number of people taking atorvastatin may have mild memory problems or confusion. If these rare effects occur, talk to your doctor.

Rarely, statins may cause or worsen diabetes. Talk to your doctor about the benefits and risks.

This drug may rarely cause muscle problems (which can rarely lead to very serious conditions called rhabdomyolysis and autoimmune myopathy). Tell your doctor right away if you develop any of these symptoms during treatment and if these symptoms persist after your doctor stops this drug: muscle pain/tenderness/weakness (especially with fever or unusual tiredness), signs of kidney problems (such as change in the amount of urine).

This medication may rarely cause liver problems. If you notice any of the following rare but serious side effects, tell your doctor right away: yellowing eyes/skin, dark urine, severe stomach/abdominal pain, persistent nausea/vomiting.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Ezetimibe + Atorvastatin?

Other medications can affect the removal of atorvastatin from your body, which may affect how atorvastatin works. Examples include colchicine, gemfibrozil, telaprevir, telithromycin, ritonavir, certain azole antifungals (such as itraconazole, ketoconazole, posaconazole), among others.

Do not take any red yeast rice products while you are taking ezetimibe/atorvastatin because some red yeast rice products may also contain a statin called lovastatin. Taking ezetimibe/atorvastatin and red yeast rice products together can increase your risk of serious muscle and liver problems.

Ezetimibe + Atorvastatin may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Ezetimibe + Atorvastatin?

Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you may do so safely. Grapefruit can increase the chance of side effects with this medicine. Ask your doctor or pharmacist for more details.

Ezetimibe + Atorvastatin may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Ezetimibe + Atorvastatin?

Ezetimibe + Atorvastatin may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using this Ezetimibe + Atorvastatin.

What is the dose of Ezetimibe + Atorvastatin for an adult?

The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Do not increase your dose or use this drug more often than prescribed. Your condition will not improve any faster, and your risk of side effects will increase.

What is the dose of Ezetimibe + Atorvastatin for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Ezetimibe + Atorvastatin available?

Ezetimibe + Atorvastatin is available in the following dosage forms and strengths:

  • Oral Tablet

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Ezetimibe + Atorvastatin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Review Date: January 29, 2018 | Last Modified: January 29, 2018

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