What is etoricoxib?

By

Generic Name: Etoricoxib Brand Name(s): Generics only. No brands available.

Know the basics

What is etoricoxib used for?

Etoricoxib is one of a group of medicines called selective COX-2 inhibitors. These belong to a family of medicines called non-steroidal anti-inflammatory drugs (NSAIDs).

Etoricoxib helps to reduce the pain and swelling (inflammation) in the joints and muscles of people with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and gout.

Etoricoxib is also used for the short term treatment of moderate pain after dental surgery.

How should I take etoricoxib?

Always take Etoricoxib exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure. Etoricoxib should not be taken by children and adolescents under 16 years of age.

Take Etoricoxib by mouth once a day.

Etoricoxib can be taken with or without food.

Do not take more than the recommended dose for your condition. Your doctor will want to discuss your treatment from time to time. It is important that you use the lowest dose that controls your pain and you should not take Etoricoxib for longer than necessary.

This is because the risk of heart attacks and strokes might increase after prolonged treatment, especially with high doses.

How do I store etoricoxib?

Etoricoxib is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Etoricoxib in the bathroom or the freezer. There may be different brands of Etoricoxib that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Etoricoxib down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Know the precautions & warnings

What should I know before using etoricoxib?

Before using Etoricoxib, tell your doctor:

  • If you are allergic (hypersensitive) to etoricoxib or any of the ingredients of Etoricoxib (see Further Information, section 6);
  • If you are allergic to non-steroidal anti-inflammatory drugs (nsaids), including aspirin and COX-2 inhibitors;
  • If you have a current stomach ulcer or bleeding in your stomach or intestines;
  • If you have serious liver disease;
  • If you have serious kidney disease;
  • If you are or could be pregnant or are breast-feeding;
  • If you are under 16 years of age;
  • If you have inflammatory bowel disease, such as Crohn’s Disease, Ulcerative Colitis or Colitis;
  • If your doctor has diagnosed heart problems including heart failure (moderate or severe types), angina (chest pain) or if you have had a heart attack, bypass surgery, peripheral arterial disease (poor circulation in legs or feet due to narrow or blocked arteries), or any kind of stroke (including mini-stroke, transient ischaemic attack or TIA).
  • Etoricoxib may slightly increase your risk of heart attack and stroke and this is why it should not be used in those who have already had heart problems or stroke;
  • If you have high blood pressure that has not been controlled by treatment (check with your doctor or nurse if you are not sure whether your blood pressure is adequately controlled);

Is it safe to take etoricoxib during pregnancy or breast-feeding?

There are no adequate studies in women for determining risk when using Etoricoxib during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Etoricoxib. Etoricoxib is pregnancy risk category  C in the first and second trimester of pregnancy, and category D in the third trimester of pregnancy according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk,
  • B=No risk in some studies,
  • C=There may be some risk,
  • D=Positive evidence of risk,
  • X=Contraindicated,
  • N=Unknown

Know the side effects

What are the side effects of etoricoxib?

Like all medicines, Etoricoxib can cause side effects, although not everybody gets them. If you develop any of these signs you should stop Etoricoxib and talk to your doctor immediately: shortness of breath; chest pains; ankle swelling appear or if they get worse; yellowing of the skin and eyes (jaundice) – these are signs of liver problems; severe or continual stomach pain or your stools become black; an allergic reaction- which can include skin problems such as ulcers or blistering, or swelling of the face, lips, tongue, or throat which may cause difficulty in breathing.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Know the interactions

What drugs may interact with etoricoxib?

Etoricoxib  may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Medicines that thin your blood (anticoagulants), such as warfarin;
  • Rifampicin (an antibiotic);
  • Methotrexate (a drug used for suppressing the immune system, and often used in rheumatoid arthritis);
  • Medicines used to help control high blood pressure and heart failure called ace inhibitors and angiotensin receptor blockers, examples include enalapril and ramipril, and losartan and valsartan.
  • Lithium (a medicine used to treat some types of depression);
  • Diuretics (water tablets);
  • Ciclosporin or tacrolimus (drugs used for suppressing the immune system);
  • Digoxin (a medicine for heart failure and irregular heart rhythm);
  • Minoxidil (a drug used to treat high blood pressure);
  • Salbutamol tablets or oral solution (a medicine for asthma) • birth control pills • hormone replacement therapy;
  • Aspirin, the risk of stomach ulcers is greater if you take etoricoxib with aspirin – etoricoxib can be taken with low-dose asprin. If you are currently taking low-dose asprin to prevent heart attacks or stroke, you should not stop taking asprin until you talk to your doctor. – do not take high-dose asprin or other anti-inflammatory medicines while taking etoricoxib;

Does food or alcohol interact with etoricoxib?

Etoricoxib may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with etoricoxib?

Etoricoxib may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have,  especially:

  • You have a history of stomach bleeding or ulcers.
  • You are dehydrated, for example by a prolonged bout of vomiting or diarrhoea.
  • You have swelling due to fluid retention.
  • You have a history of heart failure, or any other form of heart disease.
  • You have a history of high blood pressure. Etoricoxib can increase blood pressure in some people, especially in high doses, and your doctor will want to check your blood pressure from time to time.
  • You have any history of liver or kidney disease.
  • You are being treated for an infection. Etoricoxib can mask or hide a fever, which is a sign of infection.
  • You are a woman trying to become pregnant.
  • You are elderly (i.e over 65 years of age).
  • You have diabetes, high cholesterol or are a smoker. These can increase your risk of heart disease.

Understand the dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Etoricoxib.

What is the dose of Etoricoxib for an adult?

Osteoarthritis

Adult: 60 mg once daily.

Hepatic impairment:

  • Mild impairment (Child-Pugh score of 5 or 6): 60 mg once daily;
  • moderate impairment (Child-Pugh 7-9): 60 mg every other day.
  • Avoid in severehepatic impairment (Child-Pugh ≥10).

Rheumatoid arthritis

Adult:90 mg once daily.

Hepatic impairment:

  • Mild impairment (Child-Pugh score of 5 or 6): 60 mg once daily;
  • moderate impairment (Child-Pugh 7-9): 60 mg every other day.
  • Avoid in severehepatic impairment (Child-Pugh ≥10).

Acutegout

Adult:120 mg once daily. Max duration: 8 days.

Hepatic impairment:Mild impairment (Child-Pugh score of 5 or 6): 60 mg once daily; oderate impairment (Child-Pugh 7-9): 60 mg every other day. Avoid in severe hepatic impairment (Child-Pugh ≥10).

What is the dose of Etoricoxib for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Etoricoxib available?

Etoricoxib is available in the following dosage forms and strengths:

Tablet: 30 mg, 60 mg, 90 mg, 120 mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Etoricoxib, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: May 30, 2016 | Last Modified: January 4, 2017

You might also like