Generic Name: Estrone Brand Name(s): Generics only. No brands available.

Uses

What is estrone used for?

Estrone is commonly used in the treatment and prevention of:

Estrone may be prescribed for other uses, ask your doctor or pharmacist for more information.

How should I take estrone?

Follow all directions of your doctor and on your prescription label. Do not take this medicine in larger amounts or for longer than recommended.

How do I store estrone?

Estrone is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store estrone in the bathroom or the freezer. There may be different brands of estrone that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush estrone down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using estrone?

Before using this drug, there is some important information that you may notice:

  • Vaginal cream, oral tablets, transdermal form: If you think you may be pregnant, do not use any form of estrogen-containing drug. Using estrogens while you are pregnant may cause your unborn child to have birth defects. Estrogens do not prevent miscarriage.
  • Vaginal cream, oral tablets, transdermal form (if you have unusual vaginal bleeding which has not been evaluated by your doctor): Unusual vaginal bleeding can be a warning sign of cancer of the uterus, especially if it happens after menopause. Your doctor must find out the cause of the bleeding so that he or she can recommend the proper treatment. Taking estrogens without visiting your doctor can cause you serious harm if your vaginal bleeding is caused by cancer of the uterus.
  • If you have had cancer: Since estrogens increase the risk of certain types of cancer, you should not use estrogens if you have ever had cancer of the breast or uterus, unless your doctor recommends that the drug may help in cancer treatment. (For certain patients with breast or prostate cancer, estrogens may help.)
  • If you have any circulation problems: Estrogen drugs should not be used except in unusually special situations in which your doctor judges that you need estrogen therapy so much that the risks are acceptable. Men and women with abnormal blood clotting conditions should avoid estrogen.
  • When estrone do not work: During menopause, some women develop nervous symptoms or depression. Estrogens do not relieve these symptoms. You may have heard that taking estrogens for years after menopause will keep your skin soft and supple and keep you feeling young. There is no evidence for these claims and such long-term estrogen use may have serious risks.
  • After childbirth or when breastfeeding a Baby: Estrogens should not be used to try to stop the breasts from filling with milk after a baby is born. Such treatment may increase the risk of developing blood clots (see Dangers of Estrogens). If you are breastfeeding, you should avoid using any drugs because many drugs pass through to the baby in the milk. While nursing a baby, you should take drugs only on the advice of your health care provider.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using estrone during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking estrone. Estrone is pregnancy risk category X, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from estrone?

Some side effects may occur when using this drug:

  • Itching
  • Nausea
  • Vomiting
  • Bleeding
  • Others

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with estrone?

Estrone may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products may interact with this drug, including:

  • Amprenavir
  • Atazanavir
  • Carbamazepine
  • Clobazam
  • Cobicistat
  • Dabrafenib
  • Darunavir
  • Fosamprenavir
  • Fosphenytoin sodium
  • Letrozole
  • Nelfinavir mesylate
  • Phenobarbital
  • Phenytoin
  • Ritonavir
  • Saquinavir
  • Tipranavir

Does food or alcohol interact with estrone?

Estrone may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with estrone?

Estrone may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using estrone.

What is the dose of estrone for an adult?

The dose will be based on the followings (use any or all that apply):

  • Your condition
  • Other medical conditions
  • Other medications you are taking
  • How you respond to this medication
  • Your weight
  • Your height
  • Your age
  • Your gender

What is the dose of estrone for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is estrone available?

Estrone is available in the following dosage forms and strengths:

  • Estrone 2 Mg/ml Intramuscular Solution
  • Estrone 5 Mg/ml Intramuscular Solution
  • Estrone Compounding Powder

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of estrone, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: March 21, 2017 | Last Modified: March 21, 2017

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