Erenumab

By

Generic Name: Erenumab Brand Name(s): Generics only. No brands available. Avability: Rx Pregnancy Category: N

Uses

What is Erenumab used for?

Erenumab is used to help prevent migraine headaches. This medication may work by changing the amounts of certain natural substances in the brain. Erenumab belongs to a class of drugs known as monoclonal antibodies. Preventing frequent migraines can help improve your ability to concentrate and do your usual tasks.

How should I take Erenumab?

Before use, take this medication out of the refrigerator. Remove the syringe/autoinjector from the package and let it warm up to room temperature for at least 30 minutes. Do not heat this medication any other way, such as by heating in the microwave or placing in hot water. Do not leave in direct sunlight. Do not shake this medication. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid.

Before injecting each dose, clean the injection site with rubbing alcohol. Change the injection site each time to lessen injury under the skin. Do not inject into areas of skin that are tender, bruised, red, or hard. Avoid injecting into skin areas with scars or stretch marks.

Inject this medication under the skin of the thigh, abdomen, or upper arm as directed by your doctor, usually 1 time each month. The dosage is based on your medical condition and response to treatment.

Use this medication regularly to get the most benefit from it. Tell your doctor if your migraines happen more often or get worse.

How do I store Erenumab?

Erenumab is best stored in the refrigerator. To prevent drug damage, do not freeze. There may be different brands of Erenumab that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Erenumab down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Erenumab?

Before using erenumab, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

Is it safe during pregnancy or breast-feeding?

There are no adequate studies in women for determining risk when using this Erenumab during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Erenumab. Erenumab is pregnancy risk category N according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk,
  • B=No risk in some studies,
  • C=There may be some risk,
  • D=Positive evidence of risk,
  • X=Contraindicated,
  • N=Unknown

Side effects

What side effects can occur from Erenumab?

Redness, pain, or swelling at the injection site may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Erenumab?

Erenumab may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Erenumab?

Erenumab may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Erenumab?

Erenumab may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using this Erenumab.

What is the dose of Erenumab for an adult?

Usual Adult Dose for Migraine Prophylaxis

70 mg subcutaneously once a month

Some patients may benefit from 140 mg subcutaneously once a month

A dose of 140 mg should be administered as 2 consecutive subcutaneous injections of 70 mg each.

Renal Dose Adjustments

No adjustment recommended

Liver Dose Adjustments

No adjustment recommended

Dose Adjustments

Elderly: No specific recommendations, however, in general, dose selection should be cautious, generally starting at the low end of the dosing range.

What is the dose of Erenumab for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Erenumab available?

Erenumab is available in the following dosage forms and strengths:

  • Subcutaneous solution.

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Erenumab, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: November 14, 2018 | Last Modified: November 14, 2018

Want to live your best life?
Get the Hello Doktor Daily newsletter for health tips, wellness updates and more.