Edetate calcium disodium

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Generic Name: Edetate calcium disodium Brand Name(s): Generics only. No brands available.

Uses

What is edetate calcium disodium used for?

Edetate calcium disodium is commonly used for the reduction of blood levels and depot stores of lead in lead poisoning (acute and chronic) and lead encephalopathy, in both pediatric populations and adults.

Edetate calcium disodium may be prescribed for other uses; ask your doctor or pharmacist for more information.

How should I take edetate calcium disodium?

Follow all directions on your prescription label.

Do not take this medicine in larger or smaller amounts or for longer than recommended.

Edetate calcium disodium is injected into a muscle, or into a vein through an IV. A healthcare provider will give you this injection.

Ask your health care provider any questions you may have about how to use this medication.

How do I store edetate calcium disodium?

Edetate calcium disodium is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store edetate calcium disodium in the bathroom or the freezer. There may be different brands of edetate calcium disodium that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush edetate calcium disodium down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using edetate calcium disodium?

Consult with your doctor or pharmacist, if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of deetate calcium disodium or other medications.
  • You have any other illnesses, disorders, or medical conditions.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using this medication during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking this medication. This medication is pregnancy risk category B, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Breastfeeding: It is not known whether edetate calcium disodium passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Side effects

What side effects can occur from edetate calcium disodium?

Edetate calcium disodium may cause following side effects, such as:

  • Fever, chills, tired feeling, and muscle or joint pain
  • Numbness or tingly feeling
  • Tremors
  • Runny or stuffy nose
  • Sneezing
  • Water eyes
  • Mild skin rash
  • Headache
  • Pain where the medicine was injected

Seek medical attention right away if any of these severe side effects occur:

  • Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue)
  • Urinating less than usual or not at all
  • Drowsiness
  • Confusion
  • Mood changes
  • Increased thirst
  • Loss of appetite
  • Nausea and vomiting
  • Swelling
  • Weight gain
  • Feeling short of breath
  • Feeling like you might pass out
  • Fast, slow, or uneven heart rate

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with edetate calcium disodium?

Edetate calcium disodium may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with edetate calcium disodium?

Edetate calcium disodium may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with edetate calcium disodium?

Edetate calcium disodium may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Especially if you have:

  • Renal disease or hepatitis
  • Unable to urinate

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using this medication.

What is the dose of edetate calcium disodium for an adult?

  • For asymptomatic adult patients whose blood lead level is < 70 mcg/dL but > 20 mcg/dL (World Health Organization recommended upper allowable level): 1000 mg/m2/day given intravenously or intramuscularly.
  • When the blood lead level is > 70 mcg/dL or clinical symptoms consistent with lead poisoning are present, it is recommended that edetate calcium disodium be used in conjunction with BAL (dimercaprol).

Your doctor may have prescribed a different dose.

What is the dose of Edetate calcium disodium for a child?

  • For asymptomatic pediatric patients whose blood lead level is < 70 mcg/dL but > 20 mcg/dL (World Health Organization recommended upper allowable level): 1000 mg/m2/day given intravenously or intramuscularly.
  • When the blood lead level is > 70 mcg/dL or clinical symptoms consistent with lead poisoning are present, it is recommended that edetate calcium disodium be used in conjunction with BAL (dimercaprol).

How is edetate calcium disodium available?

Edetate calcium disodium is available in the following dosage forms and strengths:

  • Injectable solution 200mg/Ml

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of edetate calcium disodium, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: July 4, 2017 | Last Modified: July 4, 2017

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