Generic Name: Differin Gel Brand Name(s): Generics only. No brands available.

Uses

What is Differin gel ® (adapalene topical) used for?

Differin gel ® is a topical medicine. It is commonly used for treating severe acne in people who are at least 12 years old by decreasing acne formation.

Differin gel ® may also be used for purposes; ask your doctor for more information.

How should I take Differin gel ® (adapalene topical)?

To take Differin gel ®, you should:

  • Use Differin gel ® exactly as your doctor has prescribed it for you. Use exactly as directed on the label. Do not use in larger amounts or for longer than recommended.
  • Do not take by mouth. Differin gel ® is for use only on the skin.
  • Differin gel ® is usually applied once daily in the evening.
  • Wash your hands before applying this medicine.
  • Clean your skin with a mild non-medicated skin cleanser before applying the medicine. Pat the skin dry with a clean towel.
  • Apply a thin layer to the entire face or other affected skin areas. Avoid applying the medicine to the creases of your nose, or on your lips.
  • Do not apply to open wounds or on sunburned, windburned, dry, chapped, or irritated skin. Do not apply any other skin products unless your doctor has told you to.
  • Avoid getting this medicine in your eyes, nose, or mouth.
  • Use a skin moisturizer if your skin becomes dry while using Differin. Avoid creams or lotions that contain alpha hydroxy or glycolic acids.
  • It may take several weeks before your acne improves, and it may get slightly worse for a short time when you first start using Differin. Keep using the medication as directed, even if you think it is not working.
  • Call your doctor if skin symptoms do not begin to improve within 8 to 12 weeks of using this medicine.
  • Do not use Differin gel ® to treat any condition that has not been checked by your doctor.

How do I store Differin gel ® (adapalene topical)?

Differin gel ® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Differin gel ® in the bathroom or the freezer. There may be different brands of Differin gel ® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Differin gel ® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Differin gel ® (adapalene topical)?

Before using this gel, you should know that:

  • Tell your doctor if you are allergic to adapalene.
  • Avoid using this medication in wounds or on areas of eczema. Wait until these conditions have healed before using Differin.
  • Avoid using skin products that can cause irritation, such as harsh soaps, shampoos, or skin cleansers, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime.
  • Do not use other medication skin products unless your doctor has told you to.
  • Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Differin gel ® can make your skin more sensitive to sunlight and sunburn may result. Use a sunscreen (minimum SPF 15) and wear protective clothing if you must be out in the sun.

Is it safe during pregnancy or breastfeeding?

Pregnancy

It is not known whether Differin gel ® will harm an unborn baby. Do not use this medicine without a doctor’s advice if you are pregnant.

Breastfeeding

It is not known whether adapalene passes into breast milk or if it could harm a nursing baby. Do not use this medicine without a doctor’s advice if you are breastfeeding a baby.

Side effects

What side effects can occur from Differin gel ® (adapalene topical)?

Get emergency medical help if you have signs of an allergic reaction to Differin:

  • Hives
  • Itching
  • Chest pain
  • Difficult breathing
  • Swelling of your face, lips, tongue, or throat

Stop using this medicine and call your doctor at once if you have:

  • Skin redness, stinging, burning, or peeling after sun exposure

Some side effects may occur during the first 4 weeks of using this medicine. These side effects should become less noticeable with continued use.

Common Differin gel ® side effects may include:

  • Dry, red, or scaly skin
  • Feeling of warmth and mild stinging or burning
  • Peeling skin
  • Skin pain

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Differin gel ® (adapalene topical)?

Differin gel ® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Differin gel ® (adapalene topical)?

Differin gel ® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Differin gel ® (adapalene topical)?

Differin gel ® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Differin gel ® (adapalene topical).

What is the dose of Differin gel ® (adapalene topical) for an adult?

Gel:
Apply to the affected area once a day at bedtime after washing. A thin film should be applied, avoiding eyes, lips, angles of the nose, and mucous membranes.

Lotion:

Apply a thin film of lotion to the entire face and other affected areas of the skin once daily, after washing gently with a mild soapless cleanser. Dispense a nickel size amount of lotion (3 to 4 actuations of the pump) to cover the entire face. Avoid application to the areas of skin around eyes, lips and mucous membranes.

What is the dose of Differin gel ® (adapalene topical) for a child?

12 years old or older:

Apply to the affected area once a day at bedtime after washing. A thin film should be applied, avoiding eyes, lips, angles of the nose, and mucous membranes.

How is Differin gel ® (adapalene topical) available?

Differin gel ® is available in the following dosage forms and strengths:

  • Differin gel ® 0.1% cream, 0.1% gel, 0.3% gel

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Differin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: February 10, 2017 | Last Modified: February 10, 2017

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