Generic Name: Dicyclomine Brand Name(s): Generics only. No brands available.


What is dicyclomine used for?

Dicyclomine is commonly used for treating symptoms of irritable bowel syndrome. It may also be used for other conditions as determined by your doctor.

Dicyclomine is an anticholinergic. It works by blocking a chemical in the smooth muscle of the stomach and intestines, causing them to relax, which reduces cramping.

How should I take dicyclomine?

Use dicyclomine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Dicyclomine is usually given as an injection at your doctor office, hospital, or clinic. If you will be using dicyclomine at home, a health care provider will teach you how to use it. Be sure you understand how to use dicyclomine. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.

Dicyclomine is for intramuscular (IM) injection only. It is NOT for intravenous (IV) use.

Do not use dicyclomine if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.

Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.

The injection form of dicyclomine is only given short-term when the oral form cannot be taken. Your health care provider will prescribe the oral form of dicyclomine as soon as you are able to take it.

Use dicyclomine on a regular schedule around the clock, unless your doctor tells you otherwise.

How do I store dicyclomine?

Dicyclomine is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store dicyclomine in the bathroom or the freezer. There may be different brands of dicyclomine that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush dicyclomine down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using dicyclomine?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of dicyclomine or other medications.
  • You have any other illnesses, disorders, or medical conditions.
  • You have chronic inflammation or ulcers of the bowel, diarrhea, enlargement of the prostate, hiatal hernia, kidney or liver disease, a nervous system disease, overactive thyroid, or urinary blockage or retention.
  • You have heart disease, heart failure, a history of rapid heartbeat, or high blood pressure.
  • You are at risk for glaucoma.

Dicyclomine may cause drowsiness, dizziness, blurred vision, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use dicyclomine with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

Check with your doctor before you drink alcohol or use medicines that may cause drowsiness (e.g., sleep aids, muscle relaxers) while you are using dicyclomine; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.

Dicyclomine may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.

Do not become overheated in hot weather or while you are being active; heatstroke may occur.

Dicyclomine may make your eyes more sensitive to sunlight. It may help to wear sunglasses.

Use dicyclomine with caution in the elderly; they may be more sensitive to its effects.

Dicyclomine should not be used in children younger than 6.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using dicyclomine during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking dicyclomine. Dicyclomine is pregnancy risk category B, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from dicyclomine?

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most common side effects persist or become bothersome:

  • Blurred vision
  • Constipation
  • Decreased sweating
  • Difficulty sleeping
  • Dizziness
  • Drowsiness
  • Dry mouth
  • Headache
  • Lightheadedness
  • Loss of taste
  • Nausea
  • Nervousness

Seek medical attention right away if any of these severe side effects occur:

  • Rash
  • Hives
  • Itching
  • Difficulty breathing
  • Tightness in the chest
  • Swelling of the mouth, face, lips, or tongue
  • Agitation
  • Confusion
  • Diarrhea
  • Difficulty focusing your eyes
  • Difficulty moving
  • Difficulty speaking
  • Difficulty urinating
  • Disorientation
  • Exaggerated sense of well-being
  • Fainting
  • Hallucinations
  • Pounding in the chest
  • Rapid heartbeat
  • Short-term memory loss
  • Unusual weakness
  • Vomiting

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with dicyclomine?

Dicyclomine may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products that may interact with this drug are:

  • Amantadine, antiarrhythmics (e.g., quinidine), antihistamines (e.g., diphenhydramine), benzodiazepines (e.g., diazepam), monoamine oxidase inhibitors (MAOIs) (e.g., phenelzine), narcotic pain medicine (e.g., meperidine), nitrates (e.g., nitroglycerin, isosorbide), nitrites (e.g., sodium nitrite), phenothiazines (e.g., chlorpromazine), sympathomimetics (e.g., pseudoephedrine), or tricyclic antidepressants (e.g., amitriptyline) because they may increase the risk of dicyclomine’s side effects.
  • Metoclopramide or phenothiazines (e.g., chlorpromazine) because their effectiveness may be decreased by dicyclomine.
  • Digoxin because the risk of its side effects may be increased by dicyclomine.

Does food or alcohol interact with dicyclomine?

Dicyclomine may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with dicyclomine?

Dicyclomine may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using dicyclomine.

What is the dose of dicyclomine for an adult?

Usual Adult Dose for Irritable Bowel Syndrome


  • Initial dose: 20 mg orally four times a day
  • Maintenance dose: Up to 40 mg orally four times a day, after one week with initial dose


  • 10 to 20 mg four times a day
  • Duration of therapy: 1 or 2 weeks, when patient cannot take oral form

What is the dose of dicyclomine for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is dicyclomine available?

Dicyclomine is available in the following dosage forms and strengths:

  • Tablet

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of dicyclomine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Review Date: August 1, 2017 | Last Modified: September 2, 2017

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