Generic Name: Dicloxacillin Brand Name(s): Dicloxacillin.

Uses

What is Dicloxacillin used for?

Dicloxacillin is commonly used to treat a wide variety of bacterial infections. It is a penicillin-type antibiotic. It works by stopping the growth of bacteria.

This antibiotic treats only bacterial infections. It will not work for viral infections (e.g., common cold, flu). Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness.

How should I take Dicloxacillin?

Take this medication by mouth usually 4 times a day (every 6 hours), or as directed by your doctor. Take dicloxacillin on an empty stomach (1 hour before or 2 hours after a meal) with a full glass of water. Drink plenty of fluids while using this medication unless your doctor tells you otherwise.

The dosage is based on your medical condition and response to therapy.

For the best effect, take this antibiotic at evenly spaced times. To help you remember, take this medication at the same time(s) every day.

Continue to take this medication until the full-prescribed amount is finished even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a relapse of the infection.

Inform your doctor if your condition persists or worsens.

How do I store Dicloxacillin?

Dicloxacillin is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Dicloxacillin in the bathroom or the freezer. There may be different brands of Dicloxacillin that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Dicloxacillin down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Dicloxacillin?

Before taking dicloxacillin, tell your doctor or pharmacist if you are allergic to it; or to penicillin or cephalosporin antibiotics; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease.

Dicloxacillin may cause live bacterial vaccines (such as typhoid vaccine) to not work as well. Do not have any immunizations/vaccinations while using this medication unless your doctor tells you to.

This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.

Dicloxacillin passes into breast milk. Consult your doctor before breast-feeding.

Is it safe during pregnancy or breast-feeding?

There are no adequate studies in women for determining risk when using this Dicloxacillin during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking this Dicloxacillin. This Dicloxacillin is pregnancy risk category B according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk,
  • B=No risk in some studies,
  • C=There may be some risk,
  • D=Positive evidence of risk,
  • X=Contraindicated,
  • N=Unknown

Side effects

What side effects can occur from Dicloxacillin?

Nausea, vomiting, or diarrhea may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if any of these rare but very serious side effects occur: dark urine, persistent nausea or vomiting, stomach/abdominal pain, yellowing eyes or skin, easy bruising or bleeding, persistent sore throat or fever.

This medication may rarely cause a severe intestinal condition (Clostridium difficile-associated diarrhea) due to a type of resistant bacteria. This condition may occur during treatment or weeks to months after treatment has stopped. Do not use anti-diarrhea products or narcotic pain medications if you have any of the following symptoms because these products may make them worse. Tell your doctor right away if you develop: persistent diarrhea, abdominal or stomach pain/cramping, blood/mucus in your stool.

Use of this medication for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection (oral or vaginal fungal infection). Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge or other new symptoms.

A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Dicloxacillin?

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: methotrexate, tetracyclines, warfarin.

Although most antibiotics are unlikely to affect hormonal birth control such as pills, patch, or ring, a few antibiotics (such as rifampin, rifabutin) can decrease their effectiveness. This could result in pregnancy. If you use hormonal birth control, ask your doctor or pharmacist for more details.

Dicloxacillin may cause false positive results with certain diabetic urine testing products (cupric sulfate-type). This drug may also affect the results of certain lab tests. Make sure laboratory personnel and your doctors know you use this drug.

Dicloxacillin may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Dicloxacillin?

Dicloxacillin may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Dicloxacillin?

Dicloxacillin may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using this Dicloxacillin.

What is the dose of Dicloxacillin for an adult?

Usual Adult Dose for Bronchitis

250 to 500 mg orally every 6 hours for 10 days, depending on the nature and severity of the infection.

Usual Adult Dose for Pharyngitis

250 mg orally every 6 hours for 10 days, depending on the nature and severity of the infection.

Usual Adult Dose for Pneumonia

500 mg orally every 6 hours for up to 21 days, depending on the nature and severity of the infection.

Usual Adult Dose for Skin or Soft Tissue Infection

500 mg orally every 6 hours for 7 days, or for 3 days after acute inflammation resolves, depending on the nature and severity of the infection.

Usual Adult Dose for Upper Respiratory Tract Infection

250 mg orally every 6 hours for 7 to 21 days, depending on the nature and severity of the infection.

Precautions

Oral antibiotics are not recommended for patients with severe or life-threatening infections.

Dialysis

No adjustment recommended

Other Comments

Dicloxacillin is best absorbed when administered on an empty stomach, preferably 1 to 2 hours before meals.

What is the dose of Dicloxacillin for a child?

Usual Pediatric Dose for Skin or Soft Tissue Infection

<40 kg: 3.125 to 6.25 mg/kg orally every 6 hours.

>40 kg: 125 to 250 mg orally every 6 hours.

Usual Pediatric Dose for Upper Respiratory Tract Infection

<40 kg: 3.125 to 6.25 mg/kg orally every 6 hours.

>40 kg: 125 to 250 mg orally every 6 hours.

Usual Pediatric Dose for Osteomyelitis

Following initial intravenous therapy:

>= 1 year:

<40 kg: 12.5 to 25 mg/kg orally every 6 hours, not to exceed 2000 mg/24 hours.

>40 kg: 250 mg orally every 6 hours, not to exceed 2000 mg/24 hours.

Usual Pediatric Dose for Pneumonia

<40 kg: 6.25 mg/kg orally every 6 hours.

>40 kg: 250 mg orally every 6 hours.

How is Dicloxacillin available?

Dicloxacillin is available in the following dosage forms and strengths:

  • Capsule

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Dicloxacillin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: January 22, 2018 | Last Modified: January 22, 2018

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