What is diclofenac sodium used for?
Diclofenac sodium is commonly used to relieve pain, swelling, or inflammation caused by injuries and conditions such as osteoarthritis, rheumatoid arthritis, painful menstruation periods, migraines, and ankylosing spondylitis.
Diclofenac sodium may be prescribed for other uses; ask your doctor or pharmacist for more information.
How should I take diclofenac sodium?
Do not take this medicine in larger or smaller amounts or for longer than recommended.
Take capsule/tablet by mouth with a full glass of water, do not chew or break it, swallow the whole capsule/tablet.
Solution is given as an injection at your doctor’s office, hospital, or clinic.
Ask your health care provider any questions you may have about how to use this medication.
How do I store diclofenac sodium?
Diclofenac sodium is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store diclofenac sodium in the bathroom or the freezer. There may be different brands of diclofenac sodium that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.
You should not flush diclofenac sodium down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.
Precautions & warnings
What should I know before using diclofenac sodium?
Consult with your doctor or pharmacist, if:
- You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
- You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
- You have allergy with any of active or inactive ingredients of the product of diclofenac sodium or other medications.
- You have any other illnesses, disorders, or medical conditions.
Is it safe during pregnancy or breastfeeding?
There are no adequate studies in women for determining risk when using this medication during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking this medication. This medication is pregnancy risk category C/D if > 30 weeks after gestation; according to the US Food and Drug Administration (FDA).
FDA pregnancy risk category reference below:
- A=No risk
- B=No risk in some studies
- C=There may be some risk
- D=Positive evidence of risk
What side effects can occur from diclofenac sodium?
Diclofenac sodium may cause following side effects, such as:
- Upset stomach
Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.
What drugs may interact with diclofenac sodium?
Diclofenac sodium may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval. Some products that may interact with this drug include:
- Blood thinners, such as fondaparinux (Arixtra), dabigatran (Pradaxa) warfarin (Jantoven, Coumadin) or heparin
- Antidepressants, such as citalopram (Celexa), paroxetine (Paxil), or escitalopram (Lexapro)
- Water pills, such as hydrochlorothiazide (Esidrix, Microzide), chorthalidone (Thalitone), or chlorothiazide (Diuril)
- Beta blockers, such as acebutolol (Sectral), bisoprolol (Zebeta), atenolol (Tenormin), esmolol (Brevibloc), or carvedilol (Coreg)
- Other NSAIDS, including: celecoxib (Celebrex), naproxen (Aleve, Naprosyn), meloxicam (Mobic), nabumetone (Relafen), or etodolac (Lodine)
- Diabetes medications called sulfonylureas, such as glimepiride (Amaryl), glyburide (DiaBeta, Micronase, Glynase), and glipizide (Glucotrol)
Does food or alcohol interact with diclofenac sodium?
Diclofenac sodium may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.
What health conditions may interact with diclofenac sodium?
Diclofenac sodium may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.
Especially if you have:
- Asthma (including a history of worsening breathing after taking aspirin or other NSAIDs)
- Bleeding or clotting problems
- Heart disease (such as previous heart attack)
- High blood pressure, stroke
- Liver disease
- Growths in the nose (nasal polyps)
- Gastrointestinal problems (such as bleeding, ulcers, recurring heartburn)
The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using this medication.
What is the dose of diclofenac sodium for an adult?
- Diclofenac sodium: the recommended dose is 50 mg every 8 hours or 75 mg every 12 hours.
- Extended release: the recommended dose is 100 mg once daily; may be increased to 100 mg every 12 hours.
- Diclofenac sodium: the recommended dose is 50 mg PO every 8 hours or 75 mg every 12 hours.
- Extended release: the recommended dose is 100 mg PO once daily; may be increased to 100 mg every 12 hours.
- Zorvolex: the recommended dose is 35 mg 3 times a day.
The recommended dose is 25 mg 4 or 5 times daily.
Mild-to-Moderate Acute Pain:
Zorvolex: the recommended dose is 18 mg or 35 mg 3 times a day.
Pain (IV Administration)
Indicated for management of mild-to-moderate pain and moderate-to-severe pain alone or in combination with opioid analgesics
- Use for the shortest duration consistent with individual patient treatment goals.
- The recommended dose is 37.5 mg IV bolus injection infused over 15 seconds every 6 hours as needed, not to exceed 150 mg/day.
- To reduce the risk of renal adverse reactions, patients must be well hydrated prior to IV administration.
What is the dose of diclofenac sodium for a child?
Juvenile Idiopathic arthritis (Off-label)
- <3 years: Safety and efficacy not established
- ≥3 years: the recommended dose is 2-3 mg/kg/day for up to 4 weeks.
How is diclofenac sodium available?
Diclofenac sodium is available in the following dosage forms and strengths:
- Delayed Release Tablet 25mg, 75mg
- Extended-Release Tablet 100mg (Voltaren XR)
- Capsule 18mg (Zorvolex), 35mg (Zorvolex)
- Solution For IV Injection 37.5mg/mL (Dyloject)
What should I do in case of an emergency or overdose?
In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.
What should I do if I miss a dose?
If you miss a dose of diclofenac sodium, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.
Hello Health Group does not provide medical advice, diagnosis or treatment.
Diclofenac Sodium. http://reference.medscape.com/drug/voltaren-xr-cataflam-diclofenac-343284#6. Accessed February 25, 2017.
Diclofenac Sodium. https://www.drugs.com/diclofenac.html. Accessed February 25, 2017.
Review Date: June 2, 2017 | Last Modified: June 2, 2017