Generic Name: Diacerein Brand Name(s): Generics only. No brands available.

Uses

What is Diacerein used for?

Diacerein is a medicine that belongs to the anthraquinone class and is used to treat the symptoms associated with degenerative diseases of the bones and joints. It is used to relieve pain and swelling associated with osteoarthritis. This medicine is slow acting and is used as a long-term treatment option for osteoarthritis.

How should I take Diacerein?

The dosage is usually taken with food, twice in a day for 2-4 weeks. When it is taken with food, the rate of absorption is increased by almost 25%.

How do I store Diacerein?

Diacerein is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Diacerein in the bathroom or the freezer. There may be different brands of Diacerein that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Diacerein down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Diacerein?

Before using Diacerein, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side-effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.

  • Be careful if you having renal impairment
  • During pregnancy and breastfeeding
  • It shows maximal clinical effect after about 3 months
  • Monitor complete blood count, liver function, and urinalysis regularly while taking this medication
  • Patients with history of liver, kidney disease

Is it safe during pregnancy or breast-feeding?

There are no adequate studies in women for determining risk when using this Diacerein during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Diacerein. Diacerein is pregnancy risk category B according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk,
  • B=No risk in some studies,
  • C=There may be some risk,
  • D=Positive evidence of risk,
  • X=Contraindicated,
  • N=Unknown

Side effects

What side effects can occur from Diacerein?

  • Diarrhea
  • Stomach discomfort and pain
  • Nausea
  • Vomiting
  • Yellowing of skin and eyes
  • Intense yellow urine
  • Increase in liver enzyme levels
  • Allergic skin reaction

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Diacerein?

Diacerein may interact with the following drugs and products:

  • Aluminium hydroxide
  • Oxide
  • Psyllium husk

Diacerein may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Diacerein?

Diacerein may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Diacerein?

Diacerein may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using this Diacerein.

What is the dose of Diacerein for an adult?

Usual adult dosage for Osteoarthritis

Oral: 50 mg bid.

What is the dose of Diacerein for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Diacerein available?

Diacerein is available in the following dosage forms and strengths:

  • Oral capsule.

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Diacerein, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

 

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: April 11, 2018 | Last Modified: April 11, 2018

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