Generic Name: Dextroamphetamine Brand Name(s): Generics only. No brands available.


What is dextroamphetamine used for?

Dextroamphetamine is commonly used for treating attention deficit hyperactivity disorder (ADHD) in children. It is also used to treat a type of sleep disorder (narcolepsy). It may also be used for other conditions as determined by your doctor.

Dextroamphetamine is a central nervous system stimulant. Exactly how it works is not known. It affects certain chemicals in the brain, which may help to improve attention span and behavior.

How should I take dextroamphetamine?

Use dextroamphetamine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Take dextroamphetamine by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.

Take your doses of dextroamphetamine 4 to 6 hours apart unless your doctor tells you otherwise.

Do not drink fruit juice at the same time that you take dextroamphetamine. Certain fruit juices (e.g., grapefruit, apple, orange) may decrease dextroamphetamine’s effectiveness.

Take dextroamphetamine on a regular schedule to get the most benefit from it. Taking dextroamphetamine at the same time each day will help you remember to take it.

How do I store dextroamphetamine?

Dextroamphetamine is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store dextroamphetamine in the bathroom or the freezer. There may be different brands of dextroamphetamine that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush dextroamphetamine down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using dextroamphetamine?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of dextroamphetamine or other medications.
  • You have any other illnesses, disorders, or medical conditions.
  • You or a family member has a history of heart problems (e.g., heart failure, heart rhythm problems, heart defect), high blood pressure, thyroid problems, seizure of abnormal electroencelphalogram (EEG) test, mental or mood problems (e.g., bipolar disorder, depression, psychosis), uncontrolled muscle movements (e.g., tics), Tourette syndrome, or suicidal thoughts or attempts.
  • You have a history of stroke, growth problems, certain blood problems (e.g., porphyria), hardening of the arteries, or blood vessel problems, or you have had a recent heart attack.
  • You have a family history of sudden death or heart rhythm problems.
  • You or a family member have circulation problems in the hands or feet (e.g., Raynaud phenomenon, thromboangiitis obliterans).

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using dextroamphetamine during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking dextroamphetamine. Dextroamphetamine is pregnancy risk category C, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from dextroamphetamine?

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most common side effects persist or become bothersome:

  • Constipation
  • Diarrhea
  • Dizziness
  • Dry mouth
  • Headache
  • Loss of appetite
  • Mild weight loss
  • Nausea
  • Restlessness
  • Trouble sleeping
  • Unpleasant taste
  • Upset stomach

Seek medical attention right away if any of these severe side effects occur:

  • Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue)
  • Blurred vision or other vision changes
  • Change in sexual ability or desire
  • Chest pain or tightness
  • Dark urine
  • Decreased urination
  • Erections that happen often or that last a long time
  • Fainting
  • Fast or irregular heartbeat
  • Hallucinations
  • Muscle pain or weakness
  • New or worsening mental, mood, or behavior changes (e.g., aggression, depression, hostility, thought problems)
  • Numbness of an arm or leg
  • Seizures
  • Severe dizziness or headache
  • Shortness of breath
  • Significant weight loss or persistent loss of appetite
  • Sudden vision changes
  • Symptoms of stroke (e.g., confusion, one-sided weakness, slurred speech)
  • Tremor
  • Uncontrolled speech or muscle movements (e.g., tics)
  • Unusual weakness or tiredness
  • Vomiting

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with dextroamphetamine?

Dextroamphetamine may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products that may interact with this drug are:

  • Acetazolamide, propoxyphene, sodium bicarbonate, or thiazide diuretics (e.g., hydrochlorothiazide) because they may increase the risk of dextroamphetamine’s side effects.
  • Adrenergic blockers (e.g., guanethidine), antihistamines (e.g., diphenhydramine), ethosuximide, or medicine for high blood pressure because their effectiveness may be decreased by dextroamphetamine.
  • Ammonium chloride, ascorbic acid (vitamin C), chlorpromazine, glutamic acid, haloperidol, lithium carbonate, methenamine, reserpine, or sodium acid phosphate because they may decrease dextroamphetamine’s effectiveness.
  • Furazolidone or MAOIs (e.g., phenelzine) because the risk of severe high blood pressure, fever, headache, and decreased heart rate may be increased.
  • Meperidine, norepinephrine, phenobarbital, phenytoin, selective serotonin reuptake inhibitors (SSRIs) (e.g., fluoxetine), sympathomimetics (e.g., pseudoephedrine), or tricyclic antidepressants (e.g., desipramine) because the risk of their side effects may be increased by dextroamphetamine.

Does food or alcohol interact with dextroamphetamine?

Dextroamphetamine may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with dextroamphetamine?

Dextroamphetamine may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using dextroamphetamine.

What is the dose of dextroamphetamine for an adult?

Usual Adult Dose for Narcolepsy

Initial Dose: 10 mg orally per day

Maintenance Dose: May raise daily dose in 10 mg increments at weekly intervals until optimal response is obtained.

What is the dose of dextroamphetamine for a child?

Usual Pediatric Dose for Attention Deficit Disorder

Immediate-Release (IR):

Age 3 to 5 Years:

  • Initial Dose: 2.5 mg orally per day
  • Maintenance Dose: May raise daily dose in 2.5 mg increments at weekly intervals until optimal response is obtained.

IR and Extended-Release (ER)/Sustained-Release (SR):

Age 6 to 17 Years:

  • Initial Dose: 5 mg orally 1 or 2 times a day
  • Maintenance Dose: May raise daily dose in 5 mg increments at weekly intervals until optimal response is obtained.
  • Maximum Dose: Only in rare cases will it be necessary to exceed 40 mg per day.

Usual Pediatric Dose for Narcolepsy

Age 6 to 11 Years:

  • Initial Dose: 5 mg orally per day
  • Maintenance Dose: May raise daily dose in 5 mg increments at weekly intervals until optimal response is obtained.

Age 12 Years and Older:

  • Initial Dose: 10 mg orally per day
  • Maintenance Dose: May raise daily dose in 10 mg increments at weekly intervals until optimal response is obtained.

How is dextroamphetamine available?

Dextroamphetamine is available in the following dosage forms and strengths:

  • Tablet

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of dextroamphetamine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Review Date: August 22, 2017 | Last Modified: September 2, 2017

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