What is desloratadine?

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Generic Name: Desloratadine Brand Name(s): Generics only. No brands available.

Know the basics

What is desloratadine used for?

Desloratadine is an antihistamine used to relieve allergy symptoms such as wateryeyes, runny nose, itching eyes/nose, sneezing, hives, and itching. It works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction.

How should I take desloratadine?

Take desloratadine by mouth with or without food as directed by your doctor, usually once daily.

If you are using the rapidly-dissolving tablet, allow the tablet to dissolve on the tongue and then swallow, with or without water. Do not remove the tablet from the blister pack until right before using. If you are using the liquid form of desloratadine, carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.

The dosage is based on your age, medical condition, and response to treatment. Do not increase your dose or take desloratadine more often than directed.

Tell your doctor if your condition does not improve or if it worsens.

How do I store desloratadine?

Desloratadine is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store desloratadine in the bathroom or the freezer. There may be different brands of desloratadine that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush desloratadine down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Know the precautions & warnings

What should I know before using desloratadine?

Before taking desloratadine,

  • Tell your doctor and pharmacist if you are allergic to desloratadine, loratadine (Claritin), or any other medications.
  • Tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking.
  • Tell your doctor if you have or have ever had kidney or liver disease or phenylketonuria (for orally disintegrating tablets).
  • Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking desloratadine, call your doctor.

Is it safe to take desloratadine during pregnancy or breast-feeding?

There are no adequate studies in women for determining risk when using this medication during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking this medication. This medication is pregnancy risk category C according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk,
  • B=No risk in some studies,
  • C=There may be some risk,
  • D=Positive evidence of risk,
  • X=Contraindicated,
  • N=Unknown

Know the side effects

What are the side effects of desloratadine?

Common side effects include throat discomfort, muscle pain, nausea, indigestion, loss of appetite, diarrhea, dizziness, fatigue, trouble sleeping, nosebleeds, or dry mouth.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • Fast, pounding, or uneven heartbeat;
  • Fever, flu symptoms;
  • Seizure (convulsions);
  • Jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

  • Dry mouth, sore throat, cough;
  • Muscle pain;
  • Drowsiness, tired feeling;
  • Nausea, diarrhea;
  • Headache.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Know the interactions

What drugs may interact with desloratadine?

Desloratadine may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with desloratadine?

Desloratadine may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with desloratadine?

Desloratadine may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have, especially:

  • Liver disease;
  • Kidney disease—Effects of desloratadine may be increased because of slower removal from the body.
  • Phenylketonuria (PKU)—The oral disintegrating tablets may contain aspartame, which can make your condition worse.
  • Slow metabolizers of desloratadine—May increase chances of unwanted effects

Understand the Dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before using this medication.

What is the dose of Desloratadine for an adult?

Usual Adult Dose for Allergic Rhinitis

Initial dose: 5 mg orally once a day
Maintenance dose: 5 mg orally once a day

Usual Adult Dose for Urticaria

Initial dose: 5 mg orally once a day
Maintenance dose: 5 mg orally once a day

Usual Geriatric Dose for Allergic Rhinitis

Initial dose: 5 mg orally once a day.
Maintenance dose: 5 mg orally once a day.

Usual Geriatric Dose for Urticaria

Initial dose: 5 mg orally once a day.
Maintenance dose: 5 mg orally once a day.

What is the dose of Desloratadine for a child?

Usual Pediatric Dose for Allergic Rhinitis

>=6m <12m: 1 mg orally once a day
>=1y <6y: 1.25 mg orally once a day
>=6y <11y: 2.5 mg orally once a day
>=12 years of age: 5 mg orally once a day

Usual Pediatric Dose for Urticaria

>=6m <12m: 1 mg orally once a day
>=1y <6y: 1.25 mg orally once a day
>=6y <11y: 2.5 mg orally once a day
>=12 years of age: 5 mg orally once a day

How is desloratadine available?

Desloratadine is available in the following dosage forms and strengths:

Syrup, Oral:

Clrinex: 0.5 mg/mL (473 mL)

Tablet, Oral:

Clarinex: 5 mg

Generic: 5 mg

Tablet Dispersible, Oral:

Clarinex Reditabs: 2.5 mg, 5 mg

Generic: 2.5 mg, 5 mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of desloratadine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Review Date: May 30, 2016 | Last Modified: January 4, 2017