By Medically reviewed by hellodoktor

Generic Name: Cyclobenzaprine Brand Name(s): Generics only. No brands available.


What is cyclobenzaprine used for?

Cyclobenzaprine is commonly used for short-term to treat muscle spasms. It is usually used along with rest and physical therapy. It works by helping to relax the muscles.

How should I take cyclobenzaprine?

Take this medication by mouth with or without food as directed by your doctor, usually 3 times a day.

The dosage is based on your medical condition and response to treatment. This medication should only be used short-term (for 3 weeks or less) unless directed by your doctor. Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase.

Tell your doctor if your condition persists after 2 to 3 weeks or if it worsens.

How do I store cyclobenzaprine?

Cyclobenzaprine is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store cyclobenzaprine in the bathroom or the freezer. There may be different brands of cyclobenzaprine that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush cyclobenzaprine down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using cyclobenzaprine?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of cyclobenzaprine or other medications.
  • You have any other illnesses, disorders, or medical conditions.

Do not use cyclobenzaprine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

You should not use cyclobenzaprine if you are allergic to it, or if you have:

  • A heart rhythm disorder or you have recently had a heart attack
  • Congestive heart failure
  • Heart block
  • A thyroid disorder

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using cyclobenzaprine during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking cyclobenzaprine. Cyclobenzaprine is pregnancy risk category B, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from cyclobenzaprine?

Less serious side effects may include:

  • Dry mouth or throat
  • Blurred vision
  • Drowsiness, dizziness, tired feeling
  • Loss of appetite, stomach pain, nausea
  • Diarrhea, constipation, gas
  • Muscle weakness

Stop using cyclobenzaprine and call your doctor at once if you have any of these serious side effects:

  • Fast, pounding, or uneven heartbeats
  • Chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling
  • Sudden numbness or weakness, especially on one side of the body
  • Sudden headache, confusion, problems with vision, speech, or balance
  • Feeling light-headed, fainting
  • Confusion, weakness, lack of coordination
  • Nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes)
  • Seizure (convulsions)
  • Unusual thoughts or behavior, hallucinations (seeing things)
  • Easy bruising or bleeding, unusual weakness

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with cyclobenzaprine?

Cyclobenzaprine may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with cyclobenzaprine?

Cyclobenzaprine may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with cyclobenzaprine?

Cyclobenzaprine may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Health conditions that may interact with this drug are:

  • Glaucoma
  • Problems with urination
  • Overactive thyroid
  • Liver disease


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using cyclobenzaprine.

What is the dose of cyclobenzaprine for an adult?

Usual Adult Dose for Muscle Spasm:

Initial dose: 5 mg orally 3 times a day.

Based on individual patient response, the dose may be increased to either 7.5 mg or 10 mg 3 times a day.

Alternate doses include the 15 mg extended release capsule or 30 mg extended release capsule orally once a day.

Usual Geriatric Dose for Muscle Spasm:

Because most muscle relaxants and antispasmodic drugs can cause anticholinergic adverse events, sedation, and weakness, and because their effectiveness at doses tolerated by elderly people is questionable, cyclobenzaprine meets the Beers criteria as a medication that is potentially inappropriate for use in older adults.

The manufacturer suggests an initial dose in the elderly of 5 mg, titrating slowly upward based on individual patient response.

Extended release formulations are not recommended for use in elderly patients.

What is the dose of cyclobenzaprine for a child?

Pediatric patients 15 years of age and older:

Initial dose: 5 mg orally 3 times a day.

Based on individual patient response, the dose may be increased to either 7.5 mg or 10 mg 3 times a day.

How is cyclobenzaprine available?

Cyclobenzaprine is available in the following dosage forms and strengths:

  • Tablet 10 mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of cyclobenzaprine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

msBahasa Malaysia

Review Date: July 20, 2017 | Last Modified: September 13, 2019

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