Generic Name: Cozaar Brand Name(s): Generics only. No brands available.

Uses

What is Cozaar® (losartan) used for?

Cozaar® is an angiotensin II receptor antagonist. Losartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.

Cozaar® is used to treat high blood pressure (hypertension) in adults and children who are at least 6 years old. It is also used to lower the risk of stroke in certain people with heart disease.

Cozaar® is used to slow long-term kidney damage in people with type 2 diabetes who also have high blood pressure.

How should I take Cozaar® (losartan)?

Take Cozaar® exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.

You may take Cozaar® with or without food.

Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking this medication, which can lead to severely low blood pressure or a serious electrolyte imbalance.

Your blood pressure will need to be checked often. You may need other blood and urine tests at your doctor’s office.

It may take 3 to 6 weeks of using Cozaar® before your blood pressure is under control. For best results, keep using the medication as directed. Talk with your doctor if your condition does not improve after 3 weeks of treatment.

If you are being treated for high blood pressure, keep using this medication even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.

How do I store Cozaar® (losartan)?

Cozaar® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Cozaar® in the bathroom or the freezer. There may be different brands of Cozaar® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Cozaar® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Cozaar® (losartan)?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of Cozaar® or other medications.
  • You have any other illnesses, disorders, or medical conditions.

If you have diabetes, do not use Cozaar® together with any medication that contains aliskiren (Amturnide, Tekturna, Tekamlo).

You may also need to avoid taking Cozaar® with aliskiren if you have kidney disease.

Do not use if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away. Cozaar® can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

To make sure Cozaar® is safe for you, tell your doctor if you have:

  • Kidney disease
  • Liver disease
  • Congestive heart failure
  • An electrolyte imbalance (such as high levels of potassium in your blood)
  • If you are on a low-salt diet
  • If you are dehydrated

It is not known whether losartan passes into breast milk or if it could harm a nursing baby. You should not breastfeed while using this medicine.

Cozaar® is not approved for use by anyone younger than 6 years old.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using Cozaar® during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Cozaar®. Cozaar® is pregnancy risk category D, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from Cozaar® (losartan)?

Get emergency medical help if you have signs of an allergic reaction to Cozaar®: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • A light-headed feeling, like you might pass out
  • Pain or burning when you urinate
  • Pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating
  • Chest pain
  • High potassium – nausea, slow or unusual heart rate, weakness, loss of movement
  • Kidney problems – little or no urination, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath

Common side effects may include:

  • Dizziness
  • Dry cough
  • Back pain
  • Cold symptoms such as stuffy nose, sneezing, sore throat

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Cozaar® (losartan)?

Cozaar® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products that may interact with this drug are:

  • A diuretic or “water pill”
  • Other blood pressure medications
  • Lithium
  • Celecoxib
  • Aspirin or other NSAIDs (nonsteroidal anti-inflammatory drugs) such as ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others

Does food or alcohol interact with Cozaar® (losartan)?

Cozaar® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Cozaar® (losartan)?

Cozaar® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Cozaar® (losartan).

What is the dose of Cozaar® (losartan) for an adult?

Usual Adult Dose for Diabetic Nephropathy:

Initial dose: 50 mg orally once a day

Maintenance dose: 25 to 100 mg orally per day in 1 or 2 divided doses

Usual Adult Dose for Hypertension:

Initial dose: 50 mg orally once a day

Maintenance dose: 25 to 100 mg orally per day in 1 or 2 divided doses

What is the dose of Cozaar® (losartan) for a child?

Usual Pediatric Dose for Hypertension:

6 Years or Older:

Initial dose: 0.7 mg/kg orally once a day (up to 50 mg total)

How is Cozaar® (losartan) available?

Cozaar® is available in the following dosage forms and strengths:

  • Tablet, film coated: losartan potassium 25mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Cozaar®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: September 3, 2017 | Last Modified: September 3, 2017

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